Abstract: An oral drug delivery composition comprises a solid foam forned from a protein. The foam dissolves rapidly in the mouth. The foam contains a therapeutic agent, such as a drug, an antigen or a vaccine. The foam may be prepared by a heating, freeze-drying or vacuum drying step.
Type:
Application
Filed:
August 31, 2001
Publication date:
July 25, 2002
Applicant:
West Pharmaceutical Services Drug Delivery & Clinical Research Centre, Ltd.
Abstract: A composition is provided including: (a) a nucleic acid or an oligonucleotide; and (b) a block copolymer containing a hydrophilic block that carries functional groups that provide the block with a positive charge. These compositions may be used to deliver a nucleic acid or an oligonucleotide to a cell.
Type:
Application
Filed:
August 31, 2001
Publication date:
April 18, 2002
Applicant:
West Pharmaceutical Services Drug Delivery & Clinical Research Centre, Ltd.
Inventors:
Stanley Stewart Davis, Lisbeth Illum, Burhan Daudali
Abstract: The present invention provides a composition comprising an oil-in-water emulsion and a drug dissolved in the emulsion. The oil phase comprises a hydroxylated oil, particularly a hydroxylated vegetable oil. The preferred hydroxylated vegetable oil is castor oil.
Type:
Application
Filed:
April 24, 2001
Publication date:
December 27, 2001
Applicant:
West Pharmaceutical Services Drug Delivery & Clinical Research Centre, Ltd
Abstract: The present invention provides a composition comprising (i) fexofenadine or a pharmaceutically acceptable salt thereof and (ii) a pharmaceutical excipient that increases the solubility of the fexofenadine or salt in water. The pharmaceutical excipient is preferably a cyclodextrin.
Type:
Application
Filed:
April 13, 2001
Publication date:
December 13, 2001
Applicant:
West Pharmaceutical Services Drug Delivery & Clinical Research Centre, Ltd.
Inventors:
Lisbeth Illum, Peter James Watts, Yu-Hui Cheng