Patents Assigned to West Virginia University
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Patent number: 11972630Abstract: Various examples are provided for distortion rectification and fingerprint crossmatching. In one example, a method includes selecting an electronic, perspective distorted fingerprint sample; and generating an unwarped fingerprint sample by rectifying perspective distortions from the perspective distorted fingerprint sample by application of an unwarping transformation. Parameters of the unwarping transformation can be determined by a deep convolutional neural network (DCNN) trained on a database comprising contactless fingerprint samples suffering from perspective distortions.Type: GrantFiled: June 3, 2020Date of Patent: April 30, 2024Assignee: WEST VIRGINIA UNIVERSITYInventors: Nasser M. Nasrabadi, Jeremy M. Dawson, Ali Dabouei
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Patent number: 11939218Abstract: In one aspect, disclosed herein are devices comprising a disclosed hybrid microwave-thermal chemical reactor device. Also disclosed herein are methods of preparing hydrogen and a crystalline carbon material, such as a carbon nanotube, from methane using a hybrid heating comprising heating with both a thermal fluid and microwave irradiation of a catalyst. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: August 30, 2022Date of Patent: March 26, 2024Assignee: West Virginia University Board of Governors on Behalf of West Virginia UniversityInventors: Jianli Hu, Brandon Robinson
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Patent number: 11878014Abstract: The present invention provides a method of treating depression disease in a treatment resistant patient comprising administering to a mucosal membrane of a patient an effective amount of a pharmaceutically acceptable composition comprising an effective amount of ketamine or dextromethorphan, wherein the mucosal administration of the ketamine or dextromethorphan containing composition allows for the mucosal absorption of the composition eliminating the digestive tract of the patient for effecting a rapid acting antidepressant treatment of the treatment resistant patient. This method includes administering the composition to a patient's mucosal membrane of a respiratory tract, a genitourinary tract, an oral tract, or rectal tract of the patient. A pharmaceutically acceptable composition comprising ketamine or dextromethorphan and a vehicle is disclosed. A biomarker for identifying a depressive disease is set forth.Type: GrantFiled: September 28, 2021Date of Patent: January 23, 2024Assignee: West Virginia UniversityInventors: Scott Pollard, Patrick Marshalek, Rae Matsumoto
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Patent number: 11858818Abstract: Described herein are processes for preparation of a carbon foam material, the processes including the steps of heating in a microwave heating apparatus a mixture including a coal material and at least one additional agent. The additional agent can be a flux agent such a carbohydrate syrup, a secondary flux agent, a lignocellulosic waste material, a conductive carbon compound, a solvent, and combinations thereof. Also described are processes for calcining a carbon foam material in a furnace, a microwave heating apparatus, or an inductive field heater. The described calcining process can impart electrical conductivity and mechanical strength to carbon foams. Also described are carbon foam materials, calcined carbon foams, and composite materials. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: October 24, 2019Date of Patent: January 2, 2024Assignee: West Virginia UniversityInventor: Alfred H. Stiller
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Patent number: 11850427Abstract: Methods of improving addiction in a patient in need thereof are provided. Methods include exposing the patient to drug related cues and measuring the patient's craving levels or physiological levels during or after cue exposure to determine the patient's status or condition. Such a determination can indicate whether the patient is at risk of engaging in the addictive activity and can guide therapeutic intervention.Type: GrantFiled: December 2, 2020Date of Patent: December 26, 2023Assignee: WEST VIRGINIA UNIVERSITY BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIVERSITYInventors: Ali Rezai, Victor Finomore, James Mahoney
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Patent number: 11827954Abstract: Disclosed herein are methods for preparing a hydraulic pre-concentrate enriched in rare earth elements and critical minerals, the method comprising: (a) contacting a raw material with a first base in an amount sufficient to adjust the pH to a value from about 4.0 to about 6.0, thereby forming a mixture comprising a first aqueous phase and a first solid concentrate; (b) separating the first aqueous phase from the first solid concentrate; (c) contacting the first aqueous phase with a second base in an amount sufficient to adjust the pH to a value from about 7.0 to about 9.0, thereby forming a mixture comprising a second aqueous phase and the hydraulic pre-concentrate; (d) removing the second aqueous phase and collecting the hydraulic pre-concentrate; wherein the raw material comprises rare earth elements; and wherein the hydraulic pre-concentrate is enriched in rare earth elements.Type: GrantFiled: July 28, 2022Date of Patent: November 28, 2023Assignee: West Virginia UniversityInventors: Paul F. Ziemkiewicz, James Constant, David K. Hoffman, John D. Quaranta
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Patent number: 11805699Abstract: Disclosed herein are doped thermoelectric ceramic oxide compositions comprising a calcium cobaltite ceramic. The doped thermoelectric ceramic oxide compositions can have a formula Ca3-xM2xCo4O9M1y, where M1 represents a first metal dopant, M2 represents a second metal dopant, x is a number having a value of from about 0.00 to about 3.00, and y is a number having a value of from about 0.01 to about 0.50. The doped thermoelectric ceramic oxide compositions have an increased energy conversion efficiency as compared to an undoped or conventional thermoelectric ceramic oxide materials. Also disclosed are methods for making the doped thermoelectric ceramic oxide compositions. Products and devices are disclosed comprising the thermoelectric ceramic oxide compositions, e.g., solid-state conversion devices that can utilize heat to generate electricity. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: October 1, 2020Date of Patent: October 31, 2023Assignee: West Virginia UniversityInventors: Xueyan Song, Cesar-Octavio Romo-De-La-Cruz, Yun Chen
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Patent number: 11795070Abstract: This invention provides processes for treating a mixture of produced water and blowdown water comprising introducing produced water (PW) into blowdown water (BD) for forming a PW-BD water mixture, softening the PW-BD water mixture, subjecting the PW-BD water mixture to activated carbon filtration and reverse osmosis membrane desalination. The process generates a product water and a brine by-product.Type: GrantFiled: September 17, 2021Date of Patent: October 24, 2023Assignee: West Virginia University Board of Governors on behalf of West Virginia UniversityInventor: Lian-Shin Lin
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Patent number: 11744720Abstract: An approximation method and system are provided for more quickly controlling a prosthetic or other device by reducing computational processing time in a muscle model that can be used to control the prosthetic. For a given muscle, the approximation method can quickly compute polynomial structures for a muscle length and for each associated moment arms, which may be used to generate a torque for a joint position of a physics model. The physics model, in turn, produces a next joint position and velocity data for driving a prosthetic. The approximation method expands the polynomial structures as long as expansion is possible and sufficiently beneficial. The computations can be performed quickly by expanding the polynomial structures in a way that constrains the muscle length polynomial to the moment arm polynomial structures, and vice versa.Type: GrantFiled: September 18, 2018Date of Patent: September 5, 2023Assignee: WEST VIRGINIA UNIVERSITYInventors: Anton Sobinov, Sergiy Yakovenko, Valeriya Gritsenko, Russell Hardesty, Matthew Boots
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Patent number: 11744757Abstract: Disclosed is a leg positioner apparatus to secure placement of a leg in total hip arthroplasty procedures. The leg positioner apparatus can attach to a standard operating table and helps in positioning the operative leg for femoral preparation. The leg positioner apparatus includes a post assembly mounted to an attachment bracket. The attachment bracket can be attached to the operating table. The operative leg can rest on the post assembly during the surgical procedure.Type: GrantFiled: July 26, 2019Date of Patent: September 5, 2023Assignee: West Virginia UniversityInventor: Benjamin Frye
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Patent number: 11701417Abstract: A vaccine composition for intranasal administration includes a Bordetella pertussis antigen, and an effective adjuvant amount of a high molecular weight glucose polymer. The high molecular weight glucose polymer may be a beta-glucan. The Bordetella pertussis antigen may be an extracellular toxin, an adhesion protein, an outer membrane protein, a receptor protein, a fragment thereof, or a mixture thereof.Type: GrantFiled: March 27, 2020Date of Patent: July 18, 2023Assignee: WEST VIRGINIA UNIVERSITYInventors: Fredrick Heath Damron, Mariette Barbier
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Patent number: 11684619Abstract: The present invention provides a method of treating depression disease in a treatment resistant patient comprising administering to a mucosal membrane of a patient an effective amount of a pharmaceutically acceptable composition comprising an effective amount of ketamine or dextromethorphan, wherein the mucosal administration of the ketamine or dextromethorphan containing composition allows for the mucosal absorption of the composition eliminating the digestive tract of the patient for effecting a rapid acting antidepressant treatment of the treatment resistant patient. This method includes administering the composition to a patient's mucosal membrane of a respiratory tract, a genitourinary tract, an oral tract, or rectal tract of the patient. A pharmaceutically acceptable composition comprising ketamine or dextromethorphan and a vehicle is disclosed. A biomarker for identifying a depressive disease is set forth.Type: GrantFiled: February 4, 2022Date of Patent: June 27, 2023Assignee: West Virginia UniversityInventors: Scott Pollard, Patrick Marshalek, Rae Matsumoto
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Patent number: 11674098Abstract: In one aspect, the disclosure relates to methods for biomass gasification to produce sustainable and renewable alternatives to fossil fuels including, but not limited to syngas having a high H2 content. The method can produce an H2/CO ratio close to 2:1, which is desirable for further chemical or transportation fuel synthesis. In another aspect, the methods disclosed herein have high yields and make use of agricultural and industrial waste (e.g., hardwood pellets and grain stovers) as starting materials. In a further aspect, the methods disclosed herein can produce useful byproducts including, but not limited to, carbon nanofibers (CNF). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: December 7, 2020Date of Patent: June 13, 2023Assignee: West Virginia UniversityInventors: Jianli Hu, Amoolya D. Lalsare, Ali C. Sivri, Cosmin E. Dumitrescu
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Patent number: 11654123Abstract: This invention provides a composition comprising Formula I, or salt thereof, wherein X is chlorine, Y is a methyl group, and R is an alkyl group having a carbon chain length of three carbon atoms. A method of inhibiting osteoclast development and a method for preventing bone erosion in a patient using the compositions of Formula I are disclosed.Type: GrantFiled: May 20, 2020Date of Patent: May 23, 2023Assignees: West Virginia University, University of Pittsburgh—Of the Commonwealth System of Higher Education, Temple University—Of the Commonwealth System of Higher EducationInventors: John B. Barnett, Harry C. Blair, Jonathan Soboloff
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Patent number: 11607129Abstract: Described herein are positron emission tomography (PET)-electron paramagnetic resonance imaging (EPRI) systems and methods of use. In one example, a PET-EPRI system includes a PET-EPR insert, a PET scanner including one or more solid-state photodetectors, and a subject module that can house a subject for scanning. The PET-EPR insert includes an EPR resonator that can nest inside the PET scanner. The EPR resonator includes a resonator that can receive the subject module, a shield encircling the resonator and one or more rapid scan coils (RS-coils) positioned around the shield. The shield can prevent electrical coupling between the RS-coils and the resonator while being transparent to annihilation photons and magnetic field scans.Type: GrantFiled: June 11, 2019Date of Patent: March 21, 2023Assignee: WEST VIRGINIA UNIVERSITYInventors: Raymond R. Raylman, Alexander V. Stolin, Valery V. Khramtsov, Mark Tseytlin
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Patent number: 11600481Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to a vibrating sharp edge spray ionization (VSSI) method suitable for coupling with a mass spectrometer, a VSSI method modified with a capillary suitable for use with continuous-flow separation methods such as liquid chromatography, and a VSSI method suitable for coupling with a capillary electrophoresis (CE) device in order to introduce the CE sample flow into a mass spectrometer. Also disclosed herein are devices for carrying out these methods and methods of making the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: July 13, 2020Date of Patent: March 7, 2023Assignee: West Virginia UniversityInventors: Peng Li, Xiaojun Li, Stephen J. Valentine, Lisa Holland
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Patent number: 11565251Abstract: A microfluidic device is useful for modelling drug transmission across the vasculature and vascular barriers. The device includes a frame, a fluid-permeable lumen configured to carry a fluid through the frame in a first direction, a first chamber surrounding the lumen, and a second chamber surrounding the first fluid-permeable chamber. At least one surface of the first chamber is configured for deposition of a first population of endothelial cells. An outer surface of the second chamber is configured for deposition a second population of cells. The second chamber is configured to carry a fluid through the frame in a second direction. The fluid-permeable lumen is configured to allow the fluid to permeate through a wall of the lumen into the first chamber, and the first chamber and the second chamber are in fluid communication with each other.Type: GrantFiled: February 10, 2020Date of Patent: January 31, 2023Assignee: West Virginia UniversityInventor: Paul Lockman
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Patent number: 11560419Abstract: A recombinant collagen-like protein comprising a binding domain having binding capacity for both extra domain A and extra domain B-containing variants of cellular fibronectin. Cancer may be treated BY administering the recombinant collagen-like protein to a patient.Type: GrantFiled: December 23, 2019Date of Patent: January 24, 2023Assignee: WEST VIRGINIA UNIVERSITYInventors: Slawomir Lukomski, Dudley H. McNitt
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Patent number: 11530171Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure relates to a method for producing C4 olefins from acetylene using supported metal-based catalysts and metal-based promoters. The method is inexpensive, efficient, and environmentally sound. Additionally, the method is selective for C4 olefins and other value-added products based on changes to reaction parameters including temperature, feed gas composition, and promoter identity. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.Type: GrantFiled: April 19, 2021Date of Patent: December 20, 2022Assignee: West Virginia UniversityInventors: Jianli Hu, Qingyuan Li
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Patent number: 11506169Abstract: An apparatus for igniting a combustible mixture. In one example, the apparatus can include a coaxial cavity resonator assembly in a combustion environment. The apparatus can also include an operational feedback system and a controller. The operational feedback system can measure at least one of a voltage value and a current value of the coaxial cavity resonator assembly in the combustion environment. The controller can be configured to determine a condition of the coaxial cavity resonator assembly and modulate operation of the coaxial cavity resonator assembly based at least in part on the determined condition.Type: GrantFiled: April 22, 2021Date of Patent: November 22, 2022Assignee: WEST VIRGINIA UNIVERSITYInventors: Andrew D. Lowery, Michael J. Spencer, James E. Smith