Patents Assigned to WYSIS TECHNOLOGY FOUNDATION, INC.
  • REVERSIBLE CROSSLINKED POLYMERS
    Publication number: 20130289233
    Abstract: The present invention provides reversibly crosslinked polymers and methods for producing and using the same. In particular, reversibly crosslinked polymers of the invention comprise polyesters comprising thiol groups as crosslinking moieties. Oxidation of thiol groups affords crosslinked polymer comprising a disulfide linkage and reduction of the disulfide linkage provides non-crosslinked polymer. In some embodiments, polymers of the invention are degradable and are biocompatible.
    Type: Application
    Filed: April 29, 2013
    Publication date: October 31, 2013
    Applicant: WYSIS TECHNOLOGY FOUNDATION, INC.
    Inventor: John P. Droske
  • BIS-(HYDROXYALKYL)MERCAPTOSUCCINATES
    Publication number: 20110269903
    Abstract: The present invention provides bis(hydroxyalkyl)mercaptosuccinates of the formula: and derivatives thereof, where X1, X2, Z1, Z2, Y1, Y2, Ra, Rb, R1, and R2 are those defined herein. The present invention also provides methods for producing and using the same.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 3, 2011
    Applicant: WYSIS TECHNOLOGY FOUNDATION, INC.
    Inventors: John P. Droske, Mark J. Juetten
  • Treatment of Microbial Infections
    Publication number: 20090062337
    Abstract: The present invention provides methods for treating various microbial infections using a compound of the formula: or an isomer, tautomer, prodrug or a pharmaceutically acceptable salt thereof, wherein Y, R3, R4, R5, R6, and a are those defined herein.
    Type: Application
    Filed: August 28, 2008
    Publication date: March 5, 2009
    Applicant: WYSIS TECHNOLOGY FOUNDATION, INC.
    Inventors: William R. Schwan, Aaron Monte, Marc A. Rott, Thomas J. Volk