Abstract: An oily formulation of fulvestrant or derivatives thereof and a method for producing the same. The oily formulation comprises: fulvestrant or derivatives thereof in an amount of 10 mg/ml to 170 mg/ml; a lactate compound in an amount of 5 to 80% of the total weight of the formulation; a vegetable oil or synthetic oil (ester); an analgesic; and an optional antioxidant.
Type:
Grant
Filed:
November 15, 2012
Date of Patent:
February 25, 2020
Assignee:
XI'AN LIBANG PHARMACEUTICAL CO., LTD
Inventors:
Wudang Lu, Weiping Yu, Tao Chen, Rui Cai
Abstract: The present invention relates to a biphenyl derivative and use thereof, and the biphenyl derivative has a structure represented by the formula (I) as defined in the specification. The use refers the use of the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof, or a pharmaceutical composition comprising the biphenyl derivative or a pharmaceutically acceptable salt or solvate thereof in the preparation of a medicament for the treatment and/or prevention of ischemic stroke.
Type:
Grant
Filed:
March 11, 2016
Date of Patent:
June 25, 2019
Assignee:
XI'AN LIBANG PHARMACEUTICAL CO., LTD
Inventors:
Rutao Wang, Tao Chen, Long An, Yi Zhao, Weijiao Wang, Shupan Guo, Sa Xiao, Jinghua Pang, Huijing Hu
Abstract: This invention relates to a 2,2?,6,6?-tetraisopropyl-4,4?-biphenol lipid microsphere preparation having 2,2?,6,6?-tetraisopropyl-4,4?-biphenol as its active ingredient and formed into said lipid microsphere preparation with common medically used injection-grade oil, emulsifier, and injection-grade water.
Type:
Grant
Filed:
April 28, 2016
Date of Patent:
December 18, 2018
Assignee:
XI'AN LIBANG PHARMACEUTICAL CO., LTD
Inventors:
Rutao Wang, Tao Chen, Shupan Guo, Huijing Hu, Long An, Weijiao Wang
Abstract: Disclosed is a 2,2?,6,6?-tetraisopropyl-4,4?-biphenol soft capsule composed of a capsule shell and the contents in the capsule, wherein the contents in the capsule include 2,2?,6,6?-tetraisopropyl-4,4?-biphenol, a solvent, and an antioxidant, among others.
Type:
Grant
Filed:
August 2, 2012
Date of Patent:
July 4, 2017
Assignee:
Xi'an Libang Pharmaceutical Co., Ltd.
Inventors:
Rutao Wang, Long An, Huijing Hu, Shupan Guo, Tao Chen, Weijiao Wang
Abstract: The present invention provides 3,3?,5,5?-tetraisopropyl-4,4?-diphenol crystal forms I, II and III, and preparation methods thereof. Crystal form I is superior to crystal form II in terms of stability under high temperature, high humidity, strong light and in water medium. The preparation methods for 3,3?,5,5?-tetraisopropyl-4,4?-diphenol crystal forms I, II and III provided in the invention are simple, easy to operate and suitable for industrial production.
Abstract: Disclosed is a 2,2?,6,6?-tetraisopropyl-4,4?-biphenol soft capsule composed of a capsule shell and the contents in the capsule, wherein the contents in the capsule include 2,2?,6,6?-tetraisopropyl-4,4?-biphenol, a solvent, and an antioxidant, among others.
Type:
Application
Filed:
August 2, 2012
Publication date:
December 10, 2015
Applicant:
XI'AN LIBANG PHARMACEUTICAL CO.,LTD.
Inventors:
Rutao WANG, Long AN, Huijing HU, Shupan GUO, Tao CHEN, Weijiao WANG
Abstract: This invention relates to a 2,2?,6,6?-tetraisopropyl-4,4?-biphenol lipid microsphere preparation having 2,2?,6,6?-tetraisopropyl-4,4?-biphenol as its active ingredient and formed into said lipid microsphere preparation with common medically used injection-grade oil, emulsifier, and injection-grade water.
Type:
Application
Filed:
March 7, 2012
Publication date:
December 18, 2014
Applicant:
XI'AN LIBANG PHARMACEUTICAL CO., LTD
Inventors:
Rutao Wang, Tao Chen, Shupan Guo, Huijing Hu, Long An, Weijiao Wang