Patents Assigned to Yamanouchi Pharma Technologies, Inc.
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Publication number: 20050208133Abstract: The present invention provides compositions and methods for the multiple release of a drug in the gastrointestinal tract of a subject through the use of an oral multiple drug release system. The system provides site-specific release of the drug to both the small intestine and the colon in the form of multiple controlled doses for long-lasting efficacy, thereby reducing the drug dosing frequency.Type: ApplicationFiled: January 27, 2005Publication date: September 22, 2005Applicant: Yamanouchi Pharma Technologies, Inc.Inventors: Keiko Tsutsumi, James Chu
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Publication number: 20050100598Abstract: The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried. The tablet in the present invention is to provide stability against moisture at preserved, because the amorphous sugar changed to the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process.Type: ApplicationFiled: October 7, 2004Publication date: May 12, 2005Applicants: Yamanouchi Pharma Technologies, Inc.Inventors: Takao Mizumoto, Yoshinori Masuda, Atsushi Kajiyama, Masahiro Yanagisawa, Janaki Ram Nyshadham
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Publication number: 20050042289Abstract: A novel tablet and methods for making the tablet are provided. The tablet comprises at least one particle containing a pharmaceutically active agent and a gel-forming material comprising a first polymer, a second polymer, and a gelation facilitator agent, and has a sustained release profile for the active agent.Type: ApplicationFiled: April 28, 2004Publication date: February 24, 2005Applicant: Yamanouchi Pharma Technologies, Inc.Inventors: James Chu, Yisong Yang, Chunhong Gu, Larry Banda
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Patent number: 6803054Abstract: The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried. The tablet in the present invention is to provide stability against moisture at preserved, because the amorphous sugar changed to the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process.Type: GrantFiled: June 2, 2003Date of Patent: October 12, 2004Assignees: Yamanouchi Pharmaceutical Co., Ltd., Yamanouchi Pharma Technologies, Inc.Inventors: Takao Mizumoto, Yoshinori Masuda, Atsushi Kajiyama, Masahiro Yanagisawa, Janaki Ram Nyshadham
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Publication number: 20040091528Abstract: This invention relates to novel oral sustained-release formulations for delivery of an active agent (e.g., a drug), especially a highly water soluble drug. More particularly, this invention relates to novel formulations comprising a micelle-forming drug having a charge and at least one polymer having an opposite charge. Methods of using the novel formulations are also provided.Type: ApplicationFiled: November 12, 2002Publication date: May 13, 2004Applicants: Yamanouchi Pharma Technologies, Inc., Yamanouchi Pharmaceutical Co. Ltd.Inventors: Victoria Rogers, Philippe J.M. Dor, Joseph A. Fix, Hiroyuki Kojima, Kazuhiro Sako
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Publication number: 20030203022Abstract: The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried.Type: ApplicationFiled: June 2, 2003Publication date: October 30, 2003Applicants: Yamanouchi Pharmaceutical Co., Ltd., Yamanouchi Pharma Technologies, Inc.Inventors: Takao Mizumoto, Yoshinori Masuda, Atsushi Kajiyama, Masahiro Yanagisawa, Janaki Ram Nyshadham
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Publication number: 20030129226Abstract: The invention provides for novel compressed tablets capable of rapidly disintegrating in aqueous solutions, comprising at least one non-saccharide water soluble polymer, which are free of organic solvent residues, and methods of making such pharmaceuticals.Type: ApplicationFiled: October 9, 2002Publication date: July 10, 2003Applicant: YAMANOUCHI PHARMA TECHNOLOGIES, INC.Inventors: Fang-yu Liu, Min Michael He, Janaki Ram Nyshadham, Kuldeepak Sharma, James Shunnan Chu, Joseph A. Fix
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Patent number: 6589554Abstract: The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried. The tablet in the present invention is to provide stability against moisture at preserved, because the amorphous sugar changed to the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process.Type: GrantFiled: September 14, 2000Date of Patent: July 8, 2003Assignees: Yamanouchi Pharmaceutical Co., Ltd., Yamanouchi Pharma Technologies, Inc.Inventors: Takao Mizumoto, Yoshinori Masuda, Atsushi Kajiyama, Masahiro Yanagisawa, Janaki Ram Nyshadham
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Publication number: 20030108602Abstract: The invention provides a tablet and methods for making the tablet comprising a gel-forming material and at least one particle comprising an active agent in contact with a coating material to modify release of the active agent.Type: ApplicationFiled: July 8, 2002Publication date: June 12, 2003Applicant: Yamanouchi Pharma Technologies, Inc.Inventors: James Shunnan Chu, Yisong Yang, Joseph A. Fix