Abstract: An instrument (1) for applying a product to superficial epidermal derivatives comprising an elongated core (4) and at least one nucleus (5) supporting an applicator (6) of the product. The core (4), which is twisted, passes through the nucleus (5), and the core (4) and nucleus (5) are connected to prevent the nucleus (5) from pivoting freely on the core (4).

Abstract: An instrument (1) for applying a product such as mascara to epidermal derivatives, comprising an application means (4) for applying the product to the epidermal derivatives, wherein the instrument comprises a twisted plate (5) bearing the application means (4).

Abstract: The invention provides a cosmetic composition for topical use having anti-radical properties and including at least one plant extract of natural origin in a cosmetically acceptable medium, the composition being characterized in that said at least one plant extract of natural origin is insoluble.

Abstract: The invention concerns adult multipotent human stem cells, characterized in that they have: i) significant telomerase activity, ii) an HLA Class I negative phenotype, iii) a normal karyotype, iv) a capacity to become quiescent, v) a capacity for self-renewal preserved for at least 130 population doublings.

Abstract: The invention concerns adult multipotent human stem cells, characterized in that they have: i) significant telomerase activity, ii) an HLA Class I negative phenotype, iii) a normal karyotype, iv) a capacity to become quiescent, v) a capacity for self-renewal preserved for at least 130 population doublings.

Abstract: An instrument for applying a liquid or semi-liquid composition on the eyelashes or the eyebrows, comprising a core extending in an axial direction, and at least first, second, third, and fourth projections projecting from the core, wherein the first and second projections that form a first group of projections are mutually spaced apart by a first spacing to define a first interstitial gap in the form of a sheet extending at least locally in a plane that is substantially perpendicular to the axial direction, the first interstitial gap being shaped and dimensioned to retain the composition therein for the purpose of being applied to the eyelashes or the eyebrows, the third and fourth projections that form a second group of projections, being mutually spaced apart by a second spacing to define a second interstitial gap in the form of a sheet that extends at least locally in a plane that is substantially perpendicular to the axial direction, the interstitial gap being shaped and dimensioned to retain the composit