Abstract: In the field of medicine and medical engineering, in particular to methods and devices for diagnostics of the status of an alive organism basing on skin electrical conductivity, a method and device for monitoring galvanic skin reactions is usable in experimental and clinical medicine, as well as in psychophysiology, pedagogics and sports medicine. The device enables to eliminate interference caused by artifacts of a subject's movements as well as interference brought about by non-biological causes (various electrical noises and equipment drift). The method is featured by the fact that the shape of each pulse of the sequence of pulses is being analyzed in the phasic component frequency band. For this purpose monitored are the first and the second derivatives in time of the logarithm of skin electric conductivity. The value of the trend brought about by the tonic component is determined, and the value of the first derivative is adjusted through subtraction of the trend value from it.