Abstract: A process for preparing Erianin (Dihydro Combretastation A-4), wherein 3,4,5-trimethoxy benzaldehyde is converted to phosphonium salt or phosphonate ester or the likes thereof, then reacted with isovanillin (3-hydroxyl-4-methoxyl benzaldehyde) including a protected hydroxyl in the 3-position, followed by hydrogenation and deprotection.
Type:
Grant
Filed:
July 12, 2006
Date of Patent:
March 1, 2011
Assignee:
Zhe Jiang Cell Biomedical Research Co., Ltd.