Patents Assigned to ZHONGRONG KAITE (BEIJING) BIOTECHNOLOGY CO., LTD.
  • Patent number: 10829497
    Abstract: Disclosed are a crystal form II of a thienopyridine derivative bisulfate and a preparation method therefor and the use thereof. The X-ray powder diffraction pattern of the crystal form II represented by the 2? diffraction angle exhibits characteristic diffraction peaks at 12.86°, 13.58°, 15.58°, 17.64°, 18.42°, 21.56°, 22.90°, 23.70° and 24.64°. The crystal form can be used as an active ingredient for preparing a pharmaceutical composition for preventing and treating diseases caused by thrombi. Compared with the original crystal form, the crystal form II of the invention has a better stability, with denser bulk solid particles, and is less susceptible to static electricity, and has better fluidity and compressibility, and when used as an active ingredient for preparing a pharmaceutical composition, the pharmaceutical preparation prepared with the crystal form II has a stronger stability.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: November 10, 2020
    Assignee: ZHONGRONG KAITE (BEIJING) BIOTECHNOLOGY CO., LTD.
    Inventors: Jingkai Gu, Xueyu Xu, Hao Wang, Xue Zhao
  • Publication number: 20200207781
    Abstract: Disclosed are a crystal form II of a thienopyridine derivative bisulfate and a preparation method therefor and the use thereof. The X-ray powder diffraction pattern of the crystal form II represented by the 2? diffraction angle exhibits characteristic diffraction peaks at 12.86°, 13.58°, 15.58°, 17.64°, 18.42°, 21.56°, 22.90°, 23.70° and 24.64°. The crystal form can be used as an active ingredient for preparing a pharmaceutical composition for preventing and treating diseases caused by thrombi. Compared with the original crystal form, the crystal form II of the invention has a better stability, with denser bulk solid particles, and is less susceptible to static electricity, and has better fluidity and compressibility, and when used as an active ingredient for preparing a pharmaceutical composition, the pharmaceutical preparation prepared with the crystal form II has a stronger stability.
    Type: Application
    Filed: June 25, 2018
    Publication date: July 2, 2020
    Applicant: ZHONGRONG KAITE (BEIJING) BIOTECHNOLOGY CO., LTD.
    Inventors: JINGKAI GU, XUEYU XU, HAO WANG, XUE ZHAO