Patents Assigned to Zhuhai Sanmed Biotech LTD
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Patent number: 11880974Abstract: A method and device for detecting circulating abnormal cells. The method for detecting the circulating abnormal cells comprises: respectively segmenting and labelling, by using an image processing algorithm and a morphological algorithm, cell nuclei included in dark field microscope images of a plurality of probe channels (101); inputting the dark field microscope images, in which cell nuclei are labelled, of the plurality of probe channels into a pre-built circulating abnormal cell detection model to acquire the number of staining signals included in each labelled cell nucleus in the dark field microscope image of each probe channel (102); and for each labelled cell nucleus, on the basis of the number of the staining signals included in the labelled cell nucleus in the acquired dark field microscope image of each probe channel, determining whether the labelled cell nucleus belongs to a circulating abnormal cell (103).Type: GrantFiled: December 4, 2020Date of Patent: January 23, 2024Assignees: ZHUHAI SANMED BIOTECH LTD., ZHUHAI HENGQIN SANMED AITECH INC.Inventors: Xianjun Fan, Xingjie Lan, Xin Ye, Yi Zhang, Congsheng Li
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Patent number: 11684926Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.Type: GrantFiled: July 14, 2019Date of Patent: June 27, 2023Assignee: ZHUHAI SANMED BIOTECH LTD.Inventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
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Patent number: 11471877Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.Type: GrantFiled: July 14, 2019Date of Patent: October 18, 2022Assignee: ZHUHAI SANMED BIOTECH LTDInventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
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Publication number: 20210008543Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.Type: ApplicationFiled: July 14, 2019Publication date: January 14, 2021Applicant: Zhuhai Sanmed Biotech LTDInventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
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Publication number: 20210008565Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.Type: ApplicationFiled: July 14, 2019Publication date: January 14, 2021Applicant: Zhuhai Sanmed Biotech LTDInventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
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Publication number: 20210008566Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.Type: ApplicationFiled: July 14, 2019Publication date: January 14, 2021Applicant: Zhuhai Sanmed Biotech LTDInventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li