Patents Assigned to Zonagen, Inc.
  • Chitosan induced immunopotentiation
    Patent number: 5965144
    Abstract: Methods and compositions for potentiating an immune response are disclosed which incorporate chitosan as an immunopotentiating adjuvant. Administration of the compositions of the invention is effected by various routes.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: October 12, 1999
    Assignee: Zonagen, Inc.
    Inventors: Joseph S. Podolski, Mitzi L. Martinez
  • Chitosan induced immunopotentiation
    Patent number: 5912000
    Abstract: Methods and compositions for potentiating an immune response are disclosed which incorporate chitosan as an immunopotentiating adjuvant. Administration of the compositions of the invention is effected by various routes.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: June 15, 1999
    Assignee: Zonagen, Inc.
    Inventors: Joseph S. Podolski, Kuang Hsu, Gurpreet Singh
  • DNAs encoding mammalian ZPC and uses thereof
    Patent number: 5837497
    Abstract: A method for specifically inducing transient infertility or permanent sterility in a host animal by selective vaccination with specific zona pellucida proteins or immunocontraceptively active fragments thereof. Novel zona pellucida DNA sequences encoding specific zona pellucida proteins are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 17, 1998
    Assignee: Zonagen, Inc.
    Inventor: Jeffrey D. Harris
  • Methods of preparation and use for zona pellucida antigens and antibodies for sterilization and contraception
    Patent number: 5820863
    Abstract: The invention relates to antigenic preparations useful for inducing the production of antibodies in an individual which will bind to epitopes on zona pellucida. Also disclosed are immunogenic compositions and methods for immunizing an individual to enable the production of antibodies to zona pellucida antigens. Also disclosed are the use of these recombinant molecules and monoclonal antibodies thereto for immunocontraception or sterilization.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: October 13, 1998
    Assignee: Zonagen, Inc.
    Inventor: Bonita Sue Dunbar
  • Methods and formulations for modulating the human sexual response
    Patent number: 5731339
    Abstract: Improved methods for modulating the human sexual response by orally administering a rapidly dissolving tablet comprising phentolamine mesylate or phentolamine hydrochloride is disclosed.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: March 24, 1998
    Assignee: Zonagen, Inc.
    Inventor: Fred Lowrey
  • Methods for modulating the human sexual response
    Patent number: 5565466
    Abstract: The invention is directed to improved methods for modulating the human sexual response by administering a vasodilator to the circulation by a route of administration that avoids the "first-pass" effect.
    Type: Grant
    Filed: August 9, 1994
    Date of Patent: October 15, 1996
    Assignee: Zonagen, Inc.
    Inventors: Diane-Marie Gioco, Adrian Zorgniotti, deceased
  • Recombinantly expressed rabbit zona pellucida polypeptides
    Patent number: 4996297
    Abstract: The invention relates to antigenic preparations useful for inducing the production of antibodies in an individual which will bind to epitopes on zona pellucida. Also disclosed are immunogenic compositions and methods for immunizing an individual to enable the production of antibodies to zona pellucida antigens. Also disclosed are the use of these recombinant molecules and monoclonal antibodies thereto for immunocontraception or sterilization.
    Type: Grant
    Filed: October 7, 1987
    Date of Patent: February 26, 1991
    Assignee: Zonagen, Inc.
    Inventor: Bonita S. Dunbar