Abstract: A focus adjustment device, that provides a plurality of detection areas in an imaging region, repeatedly generates ranging values for a physical object in the detection areas, and performs focus adjustment for the physical object based on the ranging values, including a processor that has a statistical processing section, a movement state estimating section, a prediction section, and a control section, wherein the statistical processing section subjects ranging values of the plurality of detection areas to statistical processing, the movement state estimating section calculates representative values that contain statistical dispersion based on the statistical processing, and estimates movement state of the physical object based on time-series change in the representative value, the prediction section predicts focal position regarding the physical object based on the movement state that has been estimated, and the control section performs focus adjustment based on the focal position that has been predicted.

Abstract: An illumination device including an illumination source having a light source; a sensor; and a processor; and a light guiding cable having main and secondary fiber bundles. The light guiding cable comprises a first end coupled to the illumination source and an opposite second end configured for coupling with a surgical instrument such that the light source provides the surgical instrument with light from the light source. The first end is coupled to the illumination source such that light from the light source is coupled into the main fiber bundle and light guided in the secondary fiber bundle is directed to the sensor. The processor receives a signal from the sensor indicative of an illumination level at the sensor and generates a control signal if the illumination level of the sensor is above a predetermined threshold value.

Abstract: An endoscope system includes a light source apparatus to generate an illumination light including a first light in a red to near infrared region, a second light in a green region, and a third light in a blue region, an image pickup device to pick up an image of an object and output an image pickup signal, and a processor to generate a first to third color components corresponding to the first to third lights based on an image generated according to the image pickup signal. The processor generates two of three color components that are blue, green, and red included in an observation image by using a second color component, and generates one remaining color component by using a first color component, and generates respective color components of red, green, and blue included in a white light observation image by using the first to third color components.

Abstract: An insertion apparatus includes: an insertion portion including, a first conduit having a first opening, an illumination chamber having a second opening, an optical fiber configured to guide and radiate an illumination light, and an illumination lens. The first conduit is in fluid communication with an outside of the insertion portion via the first opening. The illumination chamber is configured to fluidly communicate with a peripheral part of the first conduit via the second opening. A distal end of the optical fiber is located inside of the illumination chamber. The illumination lens is configured to radiate the illumination light to the outside of the insertion portion.

Abstract: An ultrasound probe includes: an ultrasound transducer that includes a piezoelectric element configured to transmit and receive ultrasound waves to and from a subject; and an adjustment layer that is laminated on the piezoelectric element, the adjustment layer being provided with a cut surface that is cut by a blade configured to cut the piezoelectric element, the adjustment layer including an adjustment material configured to improve cutting performance of the blade.

Abstract: An image compression device of an endoscope apparatus includes a compression processing control unit, a storage unit, a first compression parameter generating unit, a second compression parameter generating unit and a compression parameter determining unit. The first compression parameter generating unit generates a first tentative compression parameter based on a transferable data amount. The second compression parameter generating unit generates a second tentative compression parameter based on a storage capacity of the storage unit. The compression parameter determining unit compares the first tentative compression parameter and the second tentative compression parameter to select a parameter with which a data amount after compression becomes smaller as a selected parameter. The compression processing control unit updates a compression parameter with the selected parameter and performs compression processing using the updated compression parameter.

Abstract: A light treatment system includes: a probe configured to be inserted into a bladder, the probe including an optical fiber, and a diffuser that is provided at a distal end of the optical fiber, the diffuser being configured to emit the light from a surface of the cylindrical shape in a diffused manner; a balloon catheter into which the probe is inserted, the balloon catheter being configured to be inserted into the bladder, the balloon catheter including a distal end portion that is to be spherically dilated in the bladder; and a liquid that includes light scattering particles and fills inside of the distal end portion when the distal end portion has been dilated, the liquid having an equivalent scattering coefficient ??s equal to or larger than 5/R, where R is a maximum radius of the distal end portion that has been dilated.

Abstract: An electrically conductive plate of a treatment instrument includes a treating surface and a back surface facing an opposite side of the treating surface, and an electric component is arranged on the back surface of the electrically conductive plate. The electric component is electrically independent from the electrically conductive plate, and a holder supports the electrically conductive plate from the back surface side. A connector is made of a thermoplastic resin, and arranged on either side of and spaced from the electric component in a width direction intersecting with a longitudinal axis. The connector stationarily fixes each end of the electrically conductive plate in the width direction to the holder.

Abstract: A tracking device includes a processor including hardware. The processor is configured to: set a start frame and an end frame in a video including multiple frames; perform forward tracking in frames subsequent to the start frame based on a region of a tracking target in the start frame; perform backward tracking in frames previous to the end frame based on a region of the tracking target in the end frame; and generate a combined mask image by combining a forward mask image based on the forward tracking with a backward mask image based on the backward tracking.

Abstract: An ultrasound imaging apparatus includes a processor including hardware. The processor is configured to: generating first frequency spectrum data and second frequency spectrum data with regard to a first ultrasound signal and a second ultrasound signal, respectively; generating first ultrasound image data based on the first ultrasound signal; generating second ultrasound image data based on the second ultrasound signal; estimating a displacement amount including at least one of a positional change amount and a rotation angle of a subject depicted in the first ultrasound image data with respect to the subject depicted in the second ultrasound image data; correcting the first frequency spectrum data in accordance with the estimated displacement amount; calculating differential feature data by using the corrected first frequency spectrum data and the second frequency spectrum data; and generating analysis image data to which color information corresponding to the differential feature data is applied.

Abstract: A light source device includes: a first and second light sources respectively emitting a first and second light beams spectra of which are different from each other; an element guiding the first and second light beams to a common optical path; a first and second sensors respectively detecting light quantities of the first and second light beams; and a controller controlling, on the basis of the detected light quantities, the light quantities of the first and second light beams. The element guides the first light beam to the path by reflecting the first light beam, the first sensor is disposed in the path, the device further includes a first and second members respectively blocking a first and second regions respectively corresponding to portions of the first and second light beams, the first sensor is disposed in the second region, and the second sensor is disposed in the first region.

Abstract: The invention relates to a system (1) comprising a medical technology device (10) controllable via a foot switch (20), and a foot switch (20), wherein the foot switch (20) comprises a transmitter and the medical technology device (10) comprises a receiver for the wireless transmission of unambiguously assignable signals for the control from the foot switch (20) to the medical technology device (10), and wherein the receiver of the medical technology device (10) is designed to measure the signal strength of signals from the foot switch (20), and the medical technology device (10) is designed to emit a warning if the measured signal strength or the signal-to-noise ratio lies below a predefined threshold value.

Abstract: A surgery system includes: an imager capturing an image of a treatment target; a display having a screen displaying the image of the treatment target captured by the imager; and a processor configured to control a display area of the treatment target on the screen, wherein the processor is configure to: calculate a position of a resection end section of the treatment target on the basis of the image of the treatment target acquired by the imager; cause the display area of the treatment target to be moved to a position at which the resection end section is disposed at a prescribed reference position on the screen; calculate an orientation of a marking added to the treatment target on the screen; and cause the display area of the treatment target to be rotated to an orientation in which the marking is disposed in a prescribed reference orientation on the screen.

Abstract: A calibration device includes a processor configured to process a stereo image which is taken by a stereo camera disposed in front end portion of an endoscope, the processor being configured to superimpose an imaging guide onto the stereo image to generate a calibration image that is to be displayed in a display, and calibrate a camera parameter of the stereo camera based on the stereo image taken by the stereo camera is state in which a plurality of marks included is a chart representing a photographic subject image in the calibration image fall into a specific positional relationship with respect to the imaging guide.

Abstract: An endoscope insertion method and an overtube are disclosed. The method is for inserting an endoscope into the vicinity of a duodenum using an overtube equipped with a raising member, and includes: adjusting an orientation of the distal end of the endoscope protruding from the overtube by the raising member to direct the distal end of the endoscope toward a pylorus; and inserting the distal end of the endoscope into the vicinity of the duodenum. The overtube includes: a tube body; and a first balloon provided on a distal end side of a distal end opening of the tube body. A center of the first balloon in a contracted state and a center of the first balloon in an expanded state are on opposite sides of a central axis of the tube body in an attaching direction of the first balloon to the tube body.

Abstract: A method for monitoring a high resistance condition at an instrument terminal of an electrosurgical generator, which includes current and voltage measuring devices for determining a current and a voltage at the terminal to determine the high resistance condition, and includes a calculation device connected to the measuring devices which is configured to evaluate the determined current and voltage, including: determining a crest factor value from the current and/or voltage, wherein the crest factor value describes a ratio of a peak value to an effective value of the current and/or voltage; comparing the determined crest factor value with a comparison value by means of a comparison device, wherein the comparison value is stored in a data storage device; and signaling a high resistance condition with a signaling device when the determined crest factor reaches or exceeds the predetermined crest factor comparison value. Also, an electrosurgical generator and electrosurgical generator system.

Abstract: An illuminating device includes an illumination light generator configured to generate illumination pulses of coherent light, and a speckle modulator configured to modulate speckle caused by the coherent light. The illumination pulse generator repeatedly generates a single illumination pulse group including a plurality of illumination pulses as a repetitive illumination pulse group.

Abstract: Provided is an image processing apparatus including a processor. The processor is configured to: reconstruct, by employing an image set acquired by means of an endoscope, three-dimensional information of an imaging subject; estimate, by means of an estimator, imaging-subject distances from the image set by employing a learning parameter; calculate, on the basis of the estimated imaging-subject distances and the imaging-subject distances in the three-dimensional information, a scale coefficient; convert relative dimensions of the three-dimensional information to absolute dimensions by employing the scale coefficient; and output the three-dimensional information containing the absolute dimensions.

Abstract: A surgical generator configured to output a high-frequency alternating voltage to a surgical ultrasound instrument. An oscillator generates a driving oscillation for an inverter generating high-frequency voltage being for the surgical instrument. A matching-coil emulation device includes a correction device acting on the driving oscillation. The correction device includes a mixing unit and a feedback circuit, modifying the driving oscillation supplied to the inverter. An estimator calculates a virtual current which would flow in the emulated matching-coil if it were present, based on this and a measured output voltage an artificial phase shift is determined for steering of the oscillator. Thereby, the transfer function is reshaped mimicking that of a physical matching coil. Accordingly, a bulky matching coil that must be precisely tuned to the ultrasound instrument and restricts use of newer and different ultrasound instruments is no longer needed.

Abstract: A medical insertion equipment system comprises a capsule including an outer shell and an interior space, a disinfectant that is located in the interior space of the capsule, and a medical insertion instrument that includes an operation section, an insertion section configured for insertion into a subject, an insertion conduit located in the insertion section, and a fixture located in the operation section, the fixture including a body having a receiver space for holding at least a portion of the capsule, and wherein the insertion conduit extends along an insertion axis from a distal end side of the insertion section to a proximal end side of the insertion section, and wherein the fixture includes an opening in a surface of the receiver space, and wherein the opening is in fluid communication with the insertion conduit via a connecting conduit.

Abstract: Provided are a forceps including: a shaft; a wire that is movable in a longitudinal direction inside the shaft; and a first arm and a second arm, each of which has a first jaw or a second jaw, that are connected to each other in a pivotable manner by means of a third joint. The first arm is connected to a distal end of the shaft in a pivotable manner by means of a first joint, and the second arm is connected to a distal end of the wire in a pivotable manner by means of a second joint. The third joint is provided between the first jaw and the first joint and between the second jaw and the second joint, and is disposed lateral to the wire in a state in which the first and second jaws are open. The first and second jaws are closed while the third joint is moving outward in the lateral direction with respect to the shaft.

Abstract: A substrate connection structure includes: a rigid substrate that includes a plurality of electrodes and a plurality of wiring patterns that are electrically connected to the plurality of electrodes; a flexible printed board that includes a plurality of flying leads formed on one end of the flexible printed board, the flying leads being electrically connected to the plurality of electrodes; and second protrusions that are arranged on the plurality of electrodes and on which the flying leads are arranged.

Abstract: An endoscope including: a handle, an elongated shaft, and a video camera disposed in the shaft. The elongated shaft having a unit including a plurality of nested tubes. The plurality of nested tubes including a first tube and a second tube at least partially disposed within the first tube, the first tube and the second tube being fixed to one another through adhesive bonding. The first tube having a first bore formed in the first tube, the first bore communicating with a first gap between the first tube and the second tube, and an adhesive is provided in the first gap.

Abstract: A shaft and an Albarran, which can be produced in a particularly simple way and can be cleaned particularly easily and time-efficiently. This is achieved by a shaft, or an optical guide tube, and at least one pull wire tube guide being formed in one piece. Owing to this one-piece configuration of the shaft, the long closed pull wire tubes can be eliminated by design. Because of the open construction of the shaft, the shaft can be cleaned particularly easily and time-efficiently. Furthermore, the production of the shaft is particularly straightforward.

Abstract: A shaft and a handheld surgical device with which an optical unit and an access article may be positioned in a simple and reliable way in the shaft. This is achieved in that at least one web, through which an optical unit is directed from the proximal end of the shaft into a bore of a shaft tip, is arranged on an inner wall of a shaft. The at least one web is configured in such a way that the distal tip of the optical unit is guided into the bore when the optical unit is inserted into the shaft, specifically regardless of the shape of the cross section of the shaft.

Abstract: A vibration transmitter includes: a first rod including a fitting hole extending along the longitudinal axis thereof; and a second rod attached to a distal end portion of the first rod by a fitting portion fitted into the fitting hole in a state where a compressed surface pressure is received from the inner surface of fitting hole. The first rod includes: a first region in which the fitting portion is fitted into the fitting hole; and a second region positioned proximal of the first region. In the first region of the first rod, a crystal grain diameter is larger than that in the second region of the first rod.

Abstract: Electrosurgical generator for providing a high-frequency alternating voltage to an electrosurgical instrument, including a control unit and an inverter for high voltage that generates a high-frequency alternating voltage fed to an output socket for the instrument. A detection unit is provided that includes a capacitive detector configured for detecting a capacitance of a plugged-in cable of the instrument. Thereby a parasitic capacitance induced by the instrument's cable can be detected. The capacitance is however low picofarad range and difficult to detect, further complicated by the requirement of galvanic separation for patient safety. However, the invention realized that just a qualitative detection is sufficient to determine whether the instrument's cable is being plugged in. The invention provides simple and efficient measurement circuit for such detection. Thereby, a safe and cost-effective plugging-in detection is realized.

Abstract: An embodiment of the present invention is an imaging system in which a camera unit and a control unit are connected by a video signal transmission line and a clock line, and the camera unit and the control unit operate in synchronization with each other by a horizontal synchronization signal and a vertical synchronization signal indicating reading timing of the video signal. The camera unit includes a signal analysis circuit configured to encode information superimposed on a master clock, and encode a register control signal superimposed on the master clock using a camera clock based on timing of the horizontal synchronization signal or the vertical synchronization signal, and write an imaging condition indicated by the register control signal to a register.

Abstract: The present application relates to a method for the cytometric analysis of multiple cell samples by a microscope for examining multiple cell samples under a microscope, wherein the microscope can be or is operated, selectively and/or alternatingly, in a transmission mode and/or in a fluorescence mode, and wherein at least one cell sample has at least one fluorescence marker. The method includes; moving the cell samples continuously in one plane relative to an optical system of the microscope having at least one microscope camera, wherein, during the movement of the cell samples, at least one or more images of a sub-region of the cell samples are recorded in the transmission mode or in the fluorescence mode and at least one or more images of the same sub-region of the cell samples are recorded in the fluorescence mode by at least one microscope camera.

Abstract: A semiconductor device includes a semiconductor substrate, a trench capacitor arranged on the semiconductor substrate, a first wiring layer, a second wiring layer, a first TSV penetrating the semiconductor substrate outside the trench capacitor, a second TSV penetrating the semiconductor substrate outside the trench capacitor, a first connecting terminal connected to the first TSV, a second connecting terminal connected to the first TSV, a third connecting terminal connected to the second TSV, and a fourth connecting terminal connected to the second TSV. A plurality of connecting terminals including the first through fourth connecting terminals are arranged dispersively over an entire area of the first wiring layer and the second wiring layer of the semiconductor device, thereby stabilizing voltage supplied to an image unit and achieving a stable image signal.

Abstract: An optical unit for endoscope includes: a moving barrel which is a soft magnetic body, configured to hold a lens; a fixed barrel which is a non-magnetic body, configured to movably hold the moving barrel on an inner circumferential face; a pair of yokes arranged on an outer face of the fixed barrel; a coil wound around the outer face of the fixed barrel and a magnet arranged on a part in the circumferential direction, between the pair of yokes; and a magnetic body member with magnetism stronger than magnetism of the moving barrel, the magnetic body member being arranged on a part of the moving barrel in the circumferential direction, corresponding to the magnet.

Abstract: An insertion device comprises an insertion section, the insertion section including a distal portion, an operation section located on a proximal end side of the insertion section, a channel located in the insertion section and communicating with the distal portion, the channel including a transformable member on a distal end side of the channel, and a transformation unit, wherein a shape of the transformable member is changeable by operation of the operation section.

Abstract: An electrosurgical generator includes a control unit, an electrosurgical function unit, and a user interface unit, wherein the electrosurgical function unit is configured to provide an electrosurgical therapy signal to one or more electrosurgical devices, the control unit is configured to control operation of the electrosurgical function and user interface units, and the user interface unit is configured to receive status information data from the control unit and to output that information to a user and allow input of user input data and to communicate that data to the control unit; wherein the user interface unit includes a proximity sensor configured to detect the presence of a user within a predetermined proximity of the user interface unit and to output a detection signal to the control unit, and the control unit is configured to switch the electrosurgical generator between first and second operational modes in response to the signal.

Abstract: A surgical device system, and methods for operating a surgical device system, includes: at least one surgical instrument, a surgical generator for providing surgical energy to at least one surgical instrument, and at least one supplementary device for providing a supplementary function to at least one of the surgical generator and/or the at least one surgical instrument; the surgical generator being configured to wirelessly communicate with the at least one supplementary device, wherein the surgical generator and the at least one supplementary device are configured to establish a first communication channel for exchanging operational data, the first communication being defined by a number of first communication channel parameters; and wherein the surgical generator the at least one supplementary device are configured to establish a second communication channel for exchanging first communication channel parameters.

Abstract: A medical apparatus comprises an insertion section inserted into a subject, a treatment instrument channel provided in the insertion section along an insertion axis extending from a proximal end to a distal end of the insertion section, a treatment instrument being inserted through the treatment instrument channel, an elastic member provided in at least a part of the treatment instrument channel, and a channel operation member for transmitting an operation force to the elastic member, and wherein the elastic member changes, according to the operation force, a sectional area of an inside of the treatment instrument channel in a direction crossing the insertion axis.

Abstract: An electrosurgical generator for operating an electrosurgical instrument, wherein the electrosurgical generator includes a data storage device coupled to the control device for storing a warning time and a switch-off time, the warning and switch-off time each being assigned to a detected instrument in order to assign an instrument-specific warning and switch-off time to each detected instrument, a time tracking device for determining an instrument-specific activation duration, wherein the activation duration is a duration of time detected from a first connection or first activation of an electrosurgical instrument connected to the instrument terminal to an actual time value, and wherein an activation duration is detected for each detected instrument, and the activation duration is recorded continuously and independently of the electrosurgical instrument operating state, and the control device triggers warning indication by triggering the signaling device when the determined activation duration exceeds the ins

Abstract: An optical system for a stereo-video endoscope, the optical system including: first and second lens system channels having first and second optical elements on first and second optical axes, respectively, the first and second optical axes being parallel to each other; wherein the first and second optical elements are each arranged symmetrically relative to each other about a plane of symmetry between the first and second lens system channels and the first and second optical elements comprise first and second D-cut lenses, respectively, each of the first and second D-cut lenses having a boundary surface which is set back relative to the plane of symmetry; and the boundary surface of each of the first and second D-cut lenses are inclined with respect of the plane of symmetry.

Abstract: An endoscope comprising an insertion section including a distal end portion, a distal end opening in a distal end surface of a distal end portion, a side opening in a side surface of the distal end portion, a suction channel located in the insertion section and extending proximally from the distal end portion, and a valve switchable between an open state and a closed state. When a first suctioning flow through the distal end opening is less than a minimum suctioning flow, the valve is in the open state and a second suctioning flow through the side opening is present, and when the first suctioning flow is more than the minimum suctioning flow, the valve is in the closed state and the second suctioning flow is absent.

Abstract: A main body for a manual surgical instrument and a manual surgical instrument, in which tools or access articles can be guided in a straightforward way through a channel, and by means of which at the same time a sufficiently large irrigation flow can be delivered through the channel. This is achieved in that two irrigation bores, which extend through a wall of a main body of a manual surgical instrument, are directed onto an upper region of a cross section of a channel running axially through the main body. In this case, the bores are arranged transversely with respect to the channel.

Abstract: A surgical equipment socket for a surgical generator for connecting surgical instruments, a surgical system and a method for detecting the use of a surgical instrument in a surgical system, wherein the surgical equipment socket includes a first indicator assembly having a first movable element, and a first detection element; wherein the first movable element is movable from a free position to a mated position, and wherein the first detection element is adapted to detect whether the first movable element is in the mated position.

Abstract: An optical scanning imaging/projection apparatus includes a light source that outputs illumination light and projection light in the visible range, an optical scanner that scans the illumination light and the projection light, which are output from the light source, along a predetermined scanning trajectory, a switch that switches the output from the light source so that the illumination light and the projection light are alternately output, an optical detector that detects observation light generated by a subject irradiated with the illumination light, a storage that stores data in which an intensity of the detected observation light detected is associated with information indicating a detection position on the scanning trajectory, and a projection light controller that controls, on the basis of the data stored in the storage unit, an intensity of the projection light to be applied to each position on the scanning trajectory.

Abstract: In an imaging system, a differential signal transmission circuit is configured to output a first signal to a first signal line in an image output period and is configured to output a second signal to a second signal line in the image output period. The first signal and the second signal are included in a differential signal. A signal output circuit is configured to output a second clock signal to the first signal line in a blanking period different from the image output period and is configured to output a second control signal to the second signal line in the blanking period. In a PLL, connection between a charge pump and a loop filter is controlled on the basis of the second control signal output to the second signal line.

Abstract: An endoscope apparatus including: a light source configured to emit illumination light including light in a first wavelength band included in a blue wavelength band, light in a first narrowband included in a green wavelength band, and light in a second narrowband having a same light absorption coefficient of hemoglobin as that of the light in the first narrowband; an imager configured to acquire a first image of an object in the first wavelength band, a first narrowband image of the object in the first narrowband, and a second narrowband image of the object in the second narrowband; and a processor including hardware. The processor is configured to implement acquiring scattering characteristics information based on a comparison result between the first narrowband image and the second narrowband image, and generating an observation image using the first image, the first narrowband image, and the scattering characteristics information.

Abstract: An optical module for endoscope includes an optical fiber, a light emitting element, a ferrule including a front surface and a back surface, and including a first through-hole into which the optical fiber is inserted, a glass substrate including a first principal surface at which the light emitting element is mounted and a second principal surface, a sleeve including a third principal surface bonded to the second principal surface of the glass substrate, and a fourth principal surface, and including a second through-hole into which the ferrule is inserted, and a stopper including a contact surface in surface contact with the back surface of the ferrule, fixed to the sleeve by using an adhesive, and further including an inner side surface in contact with a side surface of the sleeve.

Abstract: A medical data communication system including: at least one medical device; at least one wireless access point; and a central computer; wherein the at least one wireless access point and the central computer are coupled via a network; the at least one medical device comprises a logic module and a transmit/receive module coupled thereto; the transmit/receive module and the at least one wireless access point are configured to establish a wireless data link at least intermittently; and the logic module comprises at least one input interface to receive data, the logic module being configured to transmit the received data via the transmit/receive module and via the wireless data link to the access point.

Abstract: A deflection prism assembly for an endoscope having a lateral viewing direction. The deflection prism assembly including: a prism holder; a deflection prism which is received in the prism holder; and at least one electrical heating element for heating the deflection prism. The prism holder includes a reception component and an adjustment component. The deflection prism is attached to the reception component and the adjustment component provides a stop for the deflection prism in an axial direction. Wherein the at least one electrical heating element being disposed in or on the reception component; and the at least one electrical heating element at least partially extending in one or more of a circumferential direction or longitudinal direction of the reception component.

Abstract: A perfusion target internal pressure estimation method includes, at a time of a first operation for feeding liquid and not suctioning the liquid, acquiring a liquid feed flow rate in a liquid feed passage and pressure in a suction passage, at a time of a second operation for feeding the liquid and suctioning the liquid, acquiring a liquid feed flow rate in the liquid feed passage and a suction flow rate in the suction passage, subtracting the suction flow rate from the liquid feed flow rate to acquire a flow rate difference, and acquiring, based on a regression formula of the liquid feed flow rate and the pressure in the suction passage at the time of the first operation, an estimation value of an internal pressure of a perfusion target at the time of the second operation from the flow rate difference.

Abstract: An image pickup unit includes: an image pickup substrate; a first wiring plate bonded to the image pickup substrate; and a second wiring plate having a fifth principal surface, a sixth principal surface, and a second side surface, a fifth electrode on the fifth principal surface and a sixth electrode on the second side surface being bonded to a fourth electrode on the fourth principal surface of the first wiring plate by using solder, the sixth electrode being extended from the fifth electrode. A first conductor block is embedded in the second wiring plate, an exposed surface of the first conductor block on the fifth principal surface being the fifth electrode, an exposed surface of the first conductor block on the second side surface being the sixth electrode. The solder bonding the fourth and sixth electrodes forms a fillet.

Abstract: A substrate laminating apparatus includes: a first holding mechanism configured to hold a first substrate; a second holding mechanism configured to hold a second substrate and change a distance between the first substrate and the second substrate; a load detecting mechanism configured to detect a load originated from a surface tension acting between the first substrate and the second substrate; and a driving mechanism configured to control a distance between the first substrate and the second substrate based on a detection value of the load detecting mechanism.