Abstract: An electronic device includes a housing, a touchscreen display viewable through a first part of the housing, a photoplethysmogram (PPG) sensor exposed through a second part of the housing, a processor disposed in the housing and operatively connected to the touchscreen display and the PPG sensor, and a memory disposed in the housing and operatively connected to the processor, wherein the memory stores instructions that, when executed, are configured to cause the processor to receive first data from the PPG sensor, generate second data by band-pass filtering the first data, generate oxygen saturation data based on at least some of the second data, select a first portion related to a first period of time from the second data, and display, on the touchscreen display, a graphical user interface including information related to the oxygen saturation data except for data corresponding to the first portion from the graphical user interface.

Abstract: An oximeter device determines an oxygen saturation for the tissue and determines a quality value for the oxygen saturation and associated measurements of the tissue. The quality value is calculated from reflectance data received at the detectors of the oximeter device. An accelerometer of the oximeter device can detect movement of the oximeter device when oximetry measurements are made by the oximeter device. An amount of the movement is an indicator of a probe face of the oximeter device changing position with respect to the tissue when the measurements are made. The accelerometer information is used by the oximeter device to adjust the quality value to reflect the amount movement. The oxygen saturation and the adjusted quality metric value are displayed on a display of the oximeter device so that a user may view the quality of the displayed information.

Abstract: A bio-signal measuring apparatus includes: a substrate; a pulse wave measurer provided at the substrate and configured to measure pulse waves of a subject; and a pressure measurer provided at the substrate and configured to measure a contact pressure between the subject and the pulse wave measurer.

Abstract: An electronic device and method are disclosed herein. The electronic device includes a display, a printed circuit board (PCB) disposed below the display and having a first surface facing the display, a biometric sensor disposed on the first surface of the PCB and configured to measure a biometric signal related to a heartbeat, a pressure sensor disposed below the display and configured to generate a pressure signal based on measuring a pressure applied to the display, a processor. The processor implements the method, including measuring, by the biometric sensor, the biometric signal, measuring, by the pressure sensor, the pressure applied to the display, calculating biometric information related to a heartbeat by interlinking the biometric signal and the pressure signal, and outputting the calculated biometric information to the display.

Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.

Abstract: The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images.

Abstract: Systems and apparatuses for securing and protecting diabetes management devices, such as continuous glucose monitoring (CGM) devices and insulin infusion sets. An apparatus comprises a base having multiple pairs of arms which can be attached to a band. The apparatus also comprises a shell for retaining a diabetes management device and which may be unitarily formed with, or removably attached to, the base. A system may include an apparatus, a diabetes management device retained in the shell of the apparatus, and a band attached to the base of the apparatus. The band may be placed around a body part of a user, such as an arm or the abdomen. A system can include an adhesive patch which can adhere to the shell of an apparatus and which has an adhesive layer overlaid with multiple liners having cutlines formed therebetween.

Abstract: Estimation of a characteristic of a user's physiological signals can be improved using one or more calibration relationships that may be dependent on a characteristic of the optical sensor. For example, different calibration relationships can be used that are dependent on a spatial characteristic and/or that are dependent on a wavelength characteristic of the light emitting component(s) of the respective emitter of a channel. In some examples, a unique calibration relationship can be used for each channel. In some examples, a common calibration relationship can be used for multiple channels with shared distance and/or wavelength characteristics. Utilizing distance-dependent and/or wavelength-dependent calibration relationships can improve robustness of pulse oximetry measurements.

Abstract: The present disclosure describes example systems, methods, apparatuses, and medical devices for obtaining physiological parameter data from a wearable patient monitoring device. An example patient monitoring device can include an emitter and a detector. The emitter can emit light through tissue of a patient. The detector can sense the light after it passes through and is attenuated by the tissue and can generate a signal indicative of the sensed light. When the patient monitoring device is attached to or worn by the patient, the emitter and detector are aligned such that the light from the emitter travels through an opening between a first bone and a second bone of the patient prior to being sensed by the detector.

Abstract: Devices, systems, and methods for eliminating noise in non-invasive biological interrogation techniques may be described herein. A method may include taking a first set of measurements over a time period. The first set of measurements may be indicated by an electronic signal. The first set of measurements may correspond to a physiological characteristic of a subject. A change in the physiological characteristic of the subject may correspond to a change in a blood constituent of the subject. The method may include: taking a second set of measurements over the time period; correlating the first and second sets of measurements, wherein the correlating removes noise from the electronic signal; sectioning out the electronic signal; calculating an amplitude difference between two or more sections of the electronic signal; and determining a change in the amount of the blood constituent based on the difference.

Abstract: The disclosure relates to an oximeter, including a blood oxygen collecting unit that has a first light emitting unit emitting a red light, a second light emitting unit emitting an infrared light, and a light receiving sensor receiving the red light emitted by the first light emitting unit and not absorbed by a human body and the infrared light emitted by the second light emitting unit and not absorbed by the human body, and converting them into an electrical signal, a storage unit that stores measurement data and/or a power-on startup screen, the power-on startup screen including the last measurement result of a blood oxygen saturation and/or previous measurement results of the blood oxygen saturation, a power-on button that is for power-on startup, a microprocessor that calculates a blood oxygen saturation of the human body based on the electrical signal detected by the light receiving sensor.

Abstract: Monitoring apparatus for measuring the respiratory rate of a subject comprises an upper arm unit attached to a subject's upper arm in use and containing at least one movement sensor and a photoplethysmograph configured to monitor blood volume within the subject's upper arm while the upper arm unit is worn on the subjects upper arm. The output from the photoplethysmograph and movement sensor(s) are processed to calculate and output an estimate of the rate of respiration of the subject. Respiratory cycle induced variations in the photoplethysmograph signal and movement sensor signals can be independently determined and there is a greater confidence in the calculated respiratory rate when these independent calculations give consistent readings. If there is insufficient confidence, no rate of respiration is displayed.

Abstract: In some examples, a system includes processing circuitry configured to generate a laser speckle contrast signal based on a received signal indicative of detected light, wherein the detected light is scatted by tissue from a coherent light source. The processing circuitry may also determine, from the laser speckle contrast signal, a flow value and determine, from the laser speckle contrast signal, a waveform metric. Based on the flow value and the waveform metric, the processing circuitry may determine a blood flow metric for the tissue and output a representation of the blood flow metric.

Abstract: Systems and methods directed to the assessment of circulatory complications due to advancement of diabetes. Embodiments include an optical measurement device having a light source with one or more wavelengths and configured to illuminate an area of tissue, a detector configured to capture the light reflecting from one or more layers of the tissue at the one or more illumination wavelengths, a processor configured to compute, based on the detected signal of layer extracted circulatory data, one or more estimates of tissue vascular health, and a display or communication device (e.g., electronic data transfer) configured to store or report the tissue vascular health. In exemplary embodiments, the distribution of chromophores such as hemoglobin in different layers of skin is extracted using a combination of structured light in the visible and near-infrared regime.

Abstract: A system for use in monitoring application is described. The system comprises a light detection unit and an illumination arrangement. The detection unit is configured for collecting light returning from a selected inspection region for determining variations in collected light intensity. The illumination arrangement comprises one or more light sources configured for providing illumination of a selected wavelength range directed toward said inspection region. Wherein the illumination arrangement is arranged around the detection unit to provide symmetrical illumination conditions with respect to an axis connecting said detection unit and said inspection region.

Abstract: A sensor device includes a housing defining a cavity, an inlet to receive fluid pumped from an instrument device, an outlet to return the fluid to a fluid reservoir, and a fluid channel defined inside the cavity between the inlet and the outlet. A heat pump is mounted inside the cavity, and has a side surface thermally coupled to the fluid channel and an opposite side surface thermally coupled to a plate. The heat pump is configured to induce a temperature change. A sensor unit is aligned with an aperture in the plate and includes an optical component and a thermal component. The optical component configured to measure a vascular endothelial response from the induced temperature change.

Abstract: A compact optical sensor is used to determine heart rate, hemoglobin, hydration, peptides, or oxygen saturation using a light source and a single photodiode. The single photodiode has a first filter and a second filter. The first filter is closer to the light source and is transparent to green light and blocks red light. The second filter is farther from the light source and is transparent to red light and blocks green light. This arrangement of the filters facilitates acquisition of backscattered light from desired depths of measurement within the body of a user. At a first time, the light source emits red light and first output from the photodiode is determined. At a second time, the light source emits green light and second output from the photodiode is determined. The optical sensor determines oxygen saturation using the first output and heart rate using the second output.

Abstract: A measurement engine of a wearable electronic device may compensate for wavelength variations of light emitted as part of blood-oxygen saturation measurements. In some cases, determining an estimated blood-oxygen saturation value is based at least partially on temperature data that may be used to compensate for temperature-based wavelength variations of the emitted light, drive current data that may be used to compensate for drive-current-based wavelength variations of the emitted light, and/or calibration information that may be used to compensate for manufacturing variability across different light emitters. In various embodiments, the measurement engine may use temperature data, the drive current data, and/or calibration information in a variety of ways to determine estimated blood-oxygen saturation values, including using lookup tables or calibration curves, applying functions, and the like.

Abstract: An optical sensing device includes a device casing and an optical sensor on the device casing. In an embodiment, the optical sensing device further includes an image-capturing device on the device casing. The sensing direction of the optical sensor and the capturing direction of the image-capturing device point in the same direction. The image-capturing device can capture an image of an object to be sensed by the optical sensor. In another embodiment, the optical sensing device further includes a flexible shielding cover on the device casing and enclosing the optical sensor for shielding the optical sensor from external light.

Abstract: A decision support tool is provided for predicting the neonatal vitality scores of a fetus during delivery, the scores being an indicator of future health for the infant anticipated to be born within a future time interval, measured as time to birth. The predicted neonatal vitality score is determined from measurements of physiological variables monitored during labor, such as uterine activity and fetal heart rate. Fetal heart rate variability and patterns may be detected and computed using the monitored physiological variables, and neonatal vitality scores may be predicted based, at least in part, on the variability metrics and fetal heart rate patterns. Scores may be predicted for different delivery methods, such as vaginal delivery or cesarean delivery, for different time-to-birth intervals. In this way, these scores may be used for decision support for care plans during labor, such as increased monitoring and/or modifying the delivery type.