Abstract: Embodiments of the present invention are directed to a two-layer adhesive and methods of using the same to secure an electronic device to an organism. In a non-limiting embodiment of the invention, a surface of the organism is coated with a first adhesive layer (bottom layer). The first adhesive layer is cured and a surface of the cured first adhesive layer is coated with a second adhesive layer (top layer). An electronic device is positioned on the second adhesive layer prior to curing the second adhesive layer. The second adhesive layer is then cured, thereby embedding the electronic device within the second adhesive layer. The bottom layer and the top layer are selected such that the bottom layer releases upon exposure to a first solvent after a first duration and the top layer releases upon exposure to a second solvent after a second duration more than the first duration.

Abstract: Embodiments provide for methods, systems, apparatus and computer readable media for calibrating an analyte sensor upon insertion into tissue of a subject based at least in part on parameters obtained from another analyte sensor already calibrated and previously inserted into the tissue of the subject. As an example, a method may include predicting a background current associated with the newly inserted sensor, subtracting the background current from a current measured by the newly inserted sensor, and converting the subtracted current to a glucose value, the converting based at least in part on the parameters obtained from the previously inserted analyte sensor. In this way, the newly inserted sensor may be calibrated without relying on actual blood-based analyte measurements, and accuracy and sensitivity of the newly inserted sensor may be improved.

Abstract: A method for measuring sound from vortices in the carotid artery comprising: a first and second quality control provisions, wherein the quality control compares detected sounds to pre-determined sounds, and upon confirmation of the quality control procedures, detecting sounds generated by the heart and sounds from vortices in the carotid artery for at least 30 seconds. A method for determining stenosis of the carotid artery in a human patient consisting of a first step of placing a sensing device comprising an array and three sensing elements onto the patient, wherein a first sensing element is placed near the heart and the two remaining sensing elements are placed adjacent to the carotid arteries; the sensing elements then measure sounds from each of the three sensing elements, resulting in sound from three channels. The sound is measured in analog and modified to digital format and then each of the three channels are analyzed before a power spectral density analysis is performed.

Abstract: Disclosed herein is a device for repeatably and accurately measuring the threshold sensitivity of the skin on a body part or surface such as the plantar surface of the foot. The machine uses a monofilament pressure test, where a monofilament is applied to the surface of the skin until it buckles at a corresponding force. The device may measure a broad range of pressures and responsive sensation in the patient using multiple applications of the monofilament. The patient indicates a positive or negative response, based on whether the patient sensed the monofilament pressure. The machine may include a foot clamping assembly, a support chassis, a linear motion translation assembly for locating the monofilament at a given position for testing, and a camera for taking images used to identify testing locations and report results. Methods of use and testing protocols are also described herein.

Abstract: A method for measuring sound from vortices in the carotid artery comprising: first and second quality control provisions, wherein the quality control compares detected sounds to pre-determined sounds, and upon confirmation of the quality control procedures, detecting sounds generated by the heart and sounds from vortices in the carotid artery for at least 30 seconds.

Abstract: A human physical functional ability and muscle ability comprehensive assessment system includes: a force measuring system, for measuring physical quantities related to used forces of a participant during a process of completing a fitness movement by the participant; a motion capture system, for measuring physical quantities related to body posture changes of the participant during the process of completing the fitness movement; a signal collecting system, for collecting the physical quantities related to the used forces sent from the force measuring system and collecting the physical quantities related to the physical posture changes sent from the motion capture system, and for processing original data of the physical quantities with time synchronization; and an information processing system, for calculating the data after time synchronization and obtaining multiple characteristic parameters which represent muscle characteristics and/or joint characteristics.

Abstract: A method for determining proper placement of a sensor pod on a patient comprising: performing a first quality control procedure on a detection device, wherein said detection device comprises a base unit, at least two sensor pods, a computer system implementing appropriate software, and a display; wherein the first quality control procedure generates a tone from a speaker embedded within said base unit and wherein each of said sensor pods measures and compares the measured sound to a predetermined measurement in real-time; wherein a sensor pod is determined to have met quality control if said sound is within 10% of the predicted measurements; performing a second quality control procedure on said sensor pods, wherein said sensor pods measure sounds on a patient; wherein the system, once engage, detects sounds from the sensor pods and compares the detected sounds in real-time to a predicted sound based on the fluid flow vessel; and wherein said method provides for an audio or visual alarm when said sensor pod is

Abstract: An electronic device for estimating bio-information is provided. According to one embodiment, the electronic device may include a pulse wave sensor configured to measure a pulse wave signal from an object; a magnetic field detector configured to detect a change in a magnetic field generated by a magnetic field source according to a change in a force exerted by the object to the pulse wave sensor; and a processor configured to acquire a contact pressure between the object and the pulse wave sensor based on the change in the magnetic field and obtain bio-information based on the pulse wave signal and the contact pressure.

Abstract: A new born temperature and heart monitor wrap apparatus and method includes a wrap where the wrap is configured such that a new born is substantially covered by the wrap when the wrap is applied to the new born. A heart monitor device is attached to the wrap and a temperature lead retainer is attached to the wrap. A substrate is provided where the wrap is removably connected to the substrate.

Abstract: A guidewire for guidance of a catheter or of a catheter introducer sheath into a human patient. The guidewire has, when in untensioned condition, a curved deflection section at its distal end and a shaft with one or more curved steering sections proximal of a straight section proximally neighboring the deflection section. This facilitates steering a guidewire to a predetermined location inside the patient.

Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

Abstract: Monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. In some implantable device embodiments, the device includes a polymer layer comprising a material that changes volume in response to varying glucose concentrations of the aqueous humor. A pressure sensor in the device can detect the changes in volume. In some implantable device embodiments, the device includes electrodes for determining the glucose concentration.

Abstract: An intracranial pressure estimating method includes: an acquisition step (S10) of acquiring time-series data on external ear canal pressure pulse waves of a subject; an analysis step (S12) of analyzing external ear canal pressure pulse wave data obtained by digitalizing the time-series data on the external ear canal pressure pulse waves, to calculate a first formant frequency of the external ear canal pressure pulse wave data; a correction step (S13) of correcting the calculated first formant frequency based on personal information on the subject to calculate a corrected value; and an estimation step (S14) of calculating an estimated value of an intracranial pressure based on the calculated corrected value.

Abstract: A device for analyzing the regularity and symmetry of a sequence of N gait or running cycles of a person, comprising sensors for measuring raw time signals of a physical movement variable of a body segment, a processing unit connected to the sensors for measuring and configured to separate the raw time signals into distinct time signals Ci, the Ci series being associated with a given gait or running cycle i of the person, to calculate at least one similarity coefficient between the signal Ci associated with gait or running cycle i and another signal Cj associated with a gait or running cycle j of the person. A display is configured to display the matrix M(i,j) with each value of the similarity coefficient shown in the matrix M(i,j) in color to form a graduated color scale indicating the similarity between the gait or running cycles i and j.

Abstract: A swallowing diagnosis apparatus includes a controller which enables a first swallowing determination process of determining whether or not there is an aspiration risk in the swallowing on the basis of respiratory phases before and after a period in which swallowing has been estimated as having occurred; and a second swallowing determination process of extracting reference information including at least one of the sound information and the respiration information in a predetermined period including the period in which swallowing has been estimated as having occurred, obtaining a feature quantity from the extracted reference information, and performing a machine learning process on the obtained feature quantity to determine whether or not there is a possibility of dysphagia in the swallowing; and a display control process of causing a determination result obtained by the first swallowing determination process and a determination result obtained by the second swallowing determination process to be displayed.

Abstract: Systems and methods are provided for evaluating hearing health of a given user. An input audio signal is transformed into the frequency domain and a first and second hearing profile are applied to the input audio sample. The first hearing profile represents a healthy hearing standard and the second hearing profile is the given user's hearing profile. Using the hearing profiles, first and second perceptually relevant information (PRI) values are generated for the input audio sample. The first and second PRI values are analyzed against each other to generate a PRI index value for the given user, where the PRI index value is a hearing health index value for the given user. The given user's hearing profile may additionally be applied to differently processed audio samples to evaluate the amount of perceptual rescue offered by various digital signal processing algorithms.

Abstract: A smart monitoring system comprising a plurality of sensor devices within a home or facility, at least one of the plurality of sensor devices comprising sensor elements configured to detect activity of an individual in the home or facility, and a computing device configured to receive activity signals from the plurality of sensor devices associated with the individual, parse the activity signals into scoring components including a sleep score, a motion score, and an event score, compute a current scoring of the individual based on the scoring components, compare the current scoring of the individual to historic scoring and peer scoring, generate a quality of life score for the individual based on the based on the comparison, and process a clinical analysis of the individual based on the quality of life score, the clinical analysis including graphical representations of the quality of life score and the scoring components.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. In some embodiments, the devices, systems, and methods of the present disclosure are configured to assess a vessel by automatically correcting for drift in the equipment utilized to obtain measurements related to the vessel.

Abstract: Cognitive decline detection system includes obtainment unit and determination unit. Obtainment unit obtains the amount of movement during a sleep period and the amount of movement during a non-sleep period of a user for each day, the non-sleep period being the period other than the sleep period. Determination unit determines that the cognitive function of the user is lower during a determination period than during a comparison period set before the determination period when the frequency of days when a movement amount ratio falls below a predetermined ratio among days constituting the determination period is higher than that among days constituting the comparison period, the movement amount ratio representing the ratio of the amount of movement during the non-sleep period to the amount of movement during the sleep period.