Abstract: A manual breast pump includes: a body having a communicating part that communicates with space surrounded by a hood placed on a breast; a diaphragm that deforms to generate a negative pressure in the communicating part; and a handle for operation that approaches and separates from the body, wherein a colliding part, against which at least the handle and the body collide before directly contacting each other, is provided in at least a region of any of the handle, the body, and the diaphragm, the colliding part is integrally made of a same material as a material of a region in which the colliding part is arranged, and has a damper structure that absorbs an impulsive force or reduces propagation of the impulsive force and/or a cover structure in which the colliding part is covered via a gap so as not to be exposed to an outside.

Abstract: Contemplated herein is a medication mixing device which can include a housing having therein a first chamber containing a first medicament component and a second chamber provided containing a second medicament component provided with a sealing structure selectively isolating the first chamber from the second chamber. The sealing structure can include a first sealing component having a first sealing interface and a second sealing component having a second sealing interface wherein a first compression force can be applied to the first and second sealing components causes the sealing interfaces to form a seal. The first compression force can then be configured to allow the first sealing component and the second sealing component to maintain at least one degree of freedom with respect to one another.

Abstract: A device that prevents the accidental activation and lockout of an autoinjector. In illustrative embodiments, a resistance unit is configured to resist deployment of the needle until a critical force is applied by the user to the autoinjector, at which point, the resistance of the resistance unit is overcome. Continuous application of force by the user after the resistance is overcome drives the delivery device to the injection site where the medication is administered.

Abstract: A catheter assembly includes: a catheter; a catheter hub connected to the catheter; an inner needle removably disposed in the catheter; a needle hub connected to the inner needle; and a deflection suppressing member that suppresses deflection of the inner needle by supporting the inner needle via the catheter at a location distal of the catheter hub. The deflection suppressing member is supported so as to be movable relative to the needle hub in an axial direction.

Abstract: A cannula may include a bowl portion comprising a first opening and a second opening, and an insertion tube extending from the bowl portion. The insertion tube defines a passage extending from the second opening and terminating in a distal end opening. The passage is configured to receive an instrument to be advanced through the cannula. The insertion tube has a transparent portion extending proximally from the distal end opening, and a strengthened portion extending proximally from the transparent portion.

Abstract: A device for secluding a body vessel may include a distal balloon, a proximal balloon, an aspiration port positioned adjacent to the distal balloon, an injection port positioned adjacent to the proximal balloon, and a lumen assembly. The lumen assembly may comprise a central lumen, a distal balloon lumen operably coupled to the distal balloon, a proximal balloon lumen operably coupled to the proximal balloon, an aspiration port lumen operably coupled to the aspiration port, and an injection port lumen operably coupled to the injection port. The distal balloon and the proximal balloon may define a treatment chamber therebetween, and the aspiration port and the injection port may be positioned within the treatment chamber on the lumen assembly.

Abstract: An apparatus includes a housing and a pushrod. The housing defines a delivery passage and an exit port in fluid communication with the delivery passage. At least a portion of the pushrod is movably disposed in the delivery passage. A distal end portion of the pushrod is configured to move a drug dosage form through at least a portion of the delivery passage to convey the drug dosage form through the exit port when the distal end portion of the pushrod is moved from a first position to a second position. A surface of at least one of the pushrod or the housing defining the delivery passage is nonplanar, curved and/or contoured.

Abstract: The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation.

Abstract: A cannula includes a bowl portion with at least one depression in its outer surface, a tube portion, and a plurality of welds located at the at least one depression and joining the bowl portion to the tube portion. The plurality of welds may be discrete welds spaced from one another along a circumferential direction of the cannula. The weld joining a cannula bowl portion and a tube portion may be spaced from the distal end of the bowl portion. Various exemplary embodiments further contemplate methods of manufacturing a cannula by welding a tube portion and a bowl portion. Welding may occur, for example, in at least one depression of the bowl portion to form discrete welds spaced from one another along a circumferential direction of the cannula. In another example, welding may occur at a location spaced from and proximal to a distal end of the bowl portion.

Abstract: A detection device for recognizing the epidural space is provided. The detection device includes an upper case having a predetermined shape and a lower case coupled to the upper case to form a predetermined space part. A connection tube is provided at a predetermined position of the space part, one end of the connection tube communicates with a paracentesis needle part and the connection tube communicates with a pressure sensor for measuring pressure at a predetermined position of an outer peripheral part thereof. When the paracentesis needle part reaches the epidural space, the device allows a medicine injection catheter to be inserted into the connection tube thereby reaching the epidural space, with the connection tube and the paracentesis needle part connected to each other.

Abstract: An elastic and sliding valvular joint for pre-filled syringes, which comprises a single chamber with an injectable product or two chambers that contain isolated products to be mixed before the injection is described. The valvular joint acts as a temporary closure, which prevents the internal chamber from communicating with the outside, or between both internal chambers. The joint comprises two discoid cooperative elements arranged on the syringe and with its edge against the internal surface: an elastic discoid plug and a sliding receiving discoid seat. The receiving discoid seat includes a central passage tube facing the hollow cylinder, and the elastic base of the plug fits in a removable manner inside a cylindrical cavity of the opening of the central passage tube of the seat.

Abstract: A needle and syringe system that provides ultra-low dosage waste and automatic needlestick protection. A syringe assembly is provided that contains a barrel and a plunger. A tubular spacer is disposed in the barrel. A needle head assembly is provided that includes a collar and a needle. A safety slide is positioned between the needle and the collar. The safety slide has a sheathing tube that surrounds part of the needle. The safety slide can move relative the needle. In a first position, the sheathing tube does not extend beyond the sharpened end of the needle. In a second position, the sheathing tube extends beyond the sharpened end of the needle. When advanced, the plunger head moves the tubular spacer. The tubular spacer passes over the base of the needle and presses against the safety slide. The safety slide is moved from the first position to the second position.

Abstract: The present invention relates to a housing of a medical device and to a respective medical device, wherein the housing comprises a body to receive at least one device component and wherein the body is flexibly deformable in response to mechanical impact above a predefined threshold.

Abstract: A kit for the direct use of a variety of medical ampoules of differing sizes, with a syringe, the kit having: a syringe body; a syringe plunger having a hollow interior volume; and a plurality of ampoule interface elements, each one being interchangeably received within the hollow interior volume and configured for deployment between an outer surface of the medical ampoule and a surface of the hollow interior volume so as to hold the medical ampoule therein, each of the plurality of ampoule interface elements having an outside diameter sized to fit an inside diameter of the hollow interior volume, wherein a first of the ampoule interface elements has an inside diameter for receiving a medical ampoule of a first size, and a second of the ampoule interface elements has an inside diameter different from the first inside diameter for receiving a medical ampoule of a second size.

Abstract: Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to a hydrophobic active agent, and a silicone tubing having a wall permeable to the active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein the two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver a hydrophobic active agent to a target tissue, and kits that find use in performing the present method.

Abstract: A method of localized delivery of a therapeutic and/or diagnostic agent to nasal tissue or cavities includes inserting a catheter into a nasal cavity, the catheter having an outer balloon with at least one opening therethrough and an inner surface, and an inner balloon disposed in the outer balloon and at least partially enclosing an inflation chamber and having an outer surface defining a space between the outer surface of the inner balloon and the inner surface of the outer balloon, supplying the agent to the space between the outer surface of the inner balloon and the inner surface of the outer balloon via a first lumen of the catheter, and inflating the inner balloon by supplying fluid to the inflation chamber via a second lumen of the catheter to urge the agent out of the opening in the wall of the outer balloon and into nasal tissue.

Abstract: Actuators for steerable medical devices are disclosed that not only deflect or steer a portion of a medical device (e.g., a distal portion of a catheter shaft), but also include mechanisms for actively returning the deflected portion of the medical device to an initial configuration (e.g., straight or substantially straight). These active return-to-straight mechanisms may return a catheter shaft from a deflected configuration to a substantially straight configuration throughout a medical procedure, may employ one or more tension members extending along the catheter shaft, and may comprise a gross return actuator and a fine return actuator. For example, the gross return actuator may be configured to partially reverse the deflection of the distal portion of the catheter; and the fine return actuator may be configured to continue reversing the deflection. The gross return actuator may automatically trigger or actuate (mechanically or electromechanically) the fine return actuator.

Abstract: A catheter that prevents excessive concentration of stress while providing sufficient flexibility to a distal end portion of the catheter, even when the catheter is inserted and curved in patient's a blood vessel. Thus, breakage of the catheter at a radiopaque marker is prevented/reduced. The catheter includes a catheter tube and the radiopaque marker, which is disposed in the catheter tube. The radiopaque marker is fixed in the catheter so that a gap is provided between the radiopaque marker and the catheter tube in a radial direction of the catheter tube.

Abstract: The present invention provides a device (1) for monitoring the application of a drug to a patient by means of a drug pen (100), whereby the drug pen comprises a front end provided with an injection needle and a rear end provided with an actuation pushbutton, the device comprising a body (2) which can be dismountably coupled to the pen; an injection detection means determining when a drug injection is carried out; and a processing means configured for storing the date and time of the injection when the injection detection means detects that a drug injection is carried out, whereby the body is configured to be coupled to the pushbutton of the pen such that the pushbutton is actuated by pushing directly on the body, whereby the injection detection means is implemented as actuation detector configured for detecting said pushing action.

Abstract: A medication delivery system having a holding chamber capable of delivering dosages of medicament from a metered dose inhaler. The holding chamber includes an actuator detector, flow detector and display. In another embodiment, a medication delivery system includes a holding chamber having an input and an output end, a metered dose inhaler operably coupled to the input end of the holding chamber, and a metered dose inhaler identifier associated with the holding chamber and operable to identify the metered dose inhaler coupled to the holding chamber.