Patents Examined by Ali Husain Faraz
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Patent number: 11971416Abstract: An analysis apparatus (1) includes a housing unit (10) that houses a biological sample (S), a staining dispenser unit (20) that fluorescently stains the biological sample (S), an image acquisition unit (30) that acquires an image of the biological sample (S), a washer unit (40) that destains the biological sample (S), a drive unit (50), and a control unit (90) that analyzes the image and controls the drive unit (50). The control unit (90) performs adjustments so that the staining dispenser unit (20) and the housing unit (10) satisfy a first position condition, performs adjustments so that the image acquisition unit (30) and the housing unit (10) satisfy a second position condition, and performs adjustments so that the washer unit (40) and the housing unit (10) satisfy a third position condition. The analysis apparatus (1) maximizes the actual photography range of information related to the biological sample.Type: GrantFiled: June 9, 2021Date of Patent: April 30, 2024Assignees: YOKOGAWA ELECTRIC CORPORATION, University of ZurichInventors: Takayuki Kei, Yohei Tsubouchi, Lucas Pelkmans, Gabriele Gut
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Patent number: 11953505Abstract: Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.Type: GrantFiled: June 29, 2021Date of Patent: April 9, 2024Assignee: Yale UniversityInventors: Irina Buhimschi, Catalin S. Buhimschi, Michael Choma, Hemant Tagare, Stephan Michael Jonas
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Patent number: 11925455Abstract: Various methods of diagnosing and monitoring a subject infected with a Plasmodium parasite are described. Also, compositions and methods for attracting mosquitos are also described.Type: GrantFiled: August 27, 2018Date of Patent: March 12, 2024Assignee: Washington UniversityInventors: Audrey Odom John, Chad Schaber, Indi Trehan, Baranidharan Raman, Nalin Katta
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Patent number: 11926817Abstract: Apparatuses and methods are described herein for processing polynucleotides in a sealed path environment. The apparatuses include optical sensors to monitor operations and to track material usage for good manufacturing practice.Type: GrantFiled: August 10, 2020Date of Patent: March 12, 2024Assignee: NUTCRACKER THERAPEUTICS, INC.Inventors: Benjamin Eldridge, Ximiao Wen
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Patent number: 11921068Abstract: In a first step, a sample liquid is fabricated by mixing a sample formed of a polyester or decomposition products of a polyester into a solvent. The solvent used here contains chloroform and 2,2,2-trifluoroethanol and has an organic base added thereto. The organic base is at least one of a primary amine, a secondary amine, a tertiary amine and a heterocyclic amine. Next, in a second step, each of the amount of the terephthalic acid terminal and the amount of the hydroxy group terminal in the sample liquid is measured through a nuclear magnetic resonance spectroscopy aiming at hydrogen atoms. Subsequently, in a third step, the number average molecular weight of the sample is calculated from the amount of the terephthalic acid terminal and the amount of the hydroxy group terminal measured in the second step.Type: GrantFiled: May 10, 2019Date of Patent: March 5, 2024Assignee: Nippon Telegraph and Telephone CorporationInventors: Azusa Ishii, Takashi Miwa
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Patent number: 11898960Abstract: A method for rapid detection of actinides including the steps of having a support including a colorimetric complexation, placing the support in communication with a sample through urinalysis, and receiving a visual indicator from the colorimetric complexation. The sample having an unknown concentration of at least one actinide within it. The colorimetric complexation is configured to activate when contacted by a threshold concentration of an actinide.Type: GrantFiled: September 2, 2021Date of Patent: February 13, 2024Assignee: U.S. Department of EnergyInventors: Catherine Riddle, Rick L. Demmer
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Patent number: 11879862Abstract: A sensor and a method of using the sensor are disclosed. The sensor includes a conductive region in electrical communication with two electrodes, the conductive region including a MXene material combined with a mercaptoimidazolyl metal-ligand complex, wherein the MXene has the formula Mn+1Xn and M is at least one of a Group 3 transition metal, Group 4 transition metal, Group 5 transition metal, and Group 6 transition metal, X is carbon, nitrogen or a combination thereof, and n has a value of 1 to 3. The sensor can be used to detect volatile compounds that have a double or triple bond.Type: GrantFiled: December 10, 2020Date of Patent: January 23, 2024Assignee: Carrier CorporationInventors: Winston Yen-Yu Chen, Lia Antoaneta Stanciu, Alexander Wei, Aiganym Yermembetova
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Patent number: 11867647Abstract: In a first step, a sample liquid is fabricated by mixing a sample formed of a polyester or decomposition products of a polyester into a solvent. The solvent used here contains chloroform and 2,2,2-trifluoroethanol and has an organic base added thereto. The organic base is at least one of a primary amine, a secondary amine, a tertiary amine and a heterocyclic amine.Type: GrantFiled: May 10, 2019Date of Patent: January 9, 2024Assignee: Nippon Telegraph and Telephone CorporationInventors: Azusa Ishii, Takashi Miwa
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Patent number: 11852568Abstract: Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided. An example aerosol collection device includes a sample transfer adapter configured to receive a sample and a device body connected to the sample transfer adapter. In some examples, the device body defines a flow channel that guides the sample to a filter component, and the filter component contains a buffer solution.Type: GrantFiled: September 1, 2021Date of Patent: December 26, 2023Assignee: Hand Held Products, Inc.Inventors: Adam Dewey Mcbrady, Moin Shafai, Oscar Ponte Rivas, Aoife Celoria, Philip C. Foster, Dustin Michael Brandt, Giorgio Carlo Isella, Jose Guadalupe Sanchez De La Rosa, Emir Rahislic, Amanda Esther Sall Childers, Gennady Germaine, Thomas Merritt Haggerty
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Patent number: 11852567Abstract: Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided. An example aerosol collection device includes a sample transfer adapter configured to receive a sample and a device body connected to the sample transfer adapter. In some examples, the device body defines a flow channel that guides the sample to a filter component, and the filter component contains a buffer solution.Type: GrantFiled: September 1, 2021Date of Patent: December 26, 2023Assignee: Hand Held Products, Inc.Inventors: Adam Dewey McBrady, Moin Shafai, Oscar Ponte Rivas, Aoife Celoria, Philip C. Foster, Dustin Michael Brandt, Giorgio Carlo Isella, Jose Guadalupe Sanchez De La Rosa, Emir Rahislic, Amanda Esther Sall Childers, Gennady Germaine, Thomas Merritt Haggerty
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Patent number: 11845082Abstract: A specimen tube comprises a tubular body having a first end that is open, a second end that is closed and at least one side extending axially between the first end and the second end. The side and the closed end define an interior of the tube. In sonic implementations, the specimen tube comprises a plurality of foot members protruding from the second end of the tube, wherein at least a first foot member and a second foot member have different shapes from each other. In some implementations, at least one internal wall positioned within the interior of the tube defines a sample carrier holding space between at least one surface of the internal wall and an adjacent surface of the side of the tube, the sample carrier holding space being sized to store a swab inserted from the open end of the tube.Type: GrantFiled: March 25, 2021Date of Patent: December 19, 2023Assignee: Amazon Technologies, Inc.Inventor: Justinn Eddie
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Patent number: 11846574Abstract: Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided. An example aerosol collection device includes a sample transfer adapter configured to receive a sample and a device body connected to the sample transfer adapter. In some examples, the device body defines a flow channel that guides the sample to a filter component, and the filter component contains a buffer solution.Type: GrantFiled: May 5, 2021Date of Patent: December 19, 2023Assignee: Hand Held Products, Inc.Inventors: Adam Dewey McBrady, Moin Shafai, Oscar Ponte Rivas, Aoife Celoria, Philip C. Foster, Dustin Michael Brandt, Giorgio Carlo Isella, Jose Guadalupe Sanchez De La Rosa, Emir Rahislic, Amanda Esther Sall Childers, Gennady Germaine, Thomas Merritt Haggerty
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Patent number: 11841375Abstract: An automation apparatus of an analysis laboratory, for handling support devices able to support containers of biological samples. The automation apparatus includes two main automatic belt conveyors arranged in positions spaced from one another on a floor, and at least one auxiliary automatic belt conveyor. The auxiliary belt conveyor is spaced at a different height with respect to the main conveyors, and is operatively connected to the main conveyors by means of lift devices.Type: GrantFiled: December 14, 2020Date of Patent: December 12, 2023Assignee: Inpeco Holding Ltd.Inventor: Gianandrea Pedrazzini
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Patent number: 11835462Abstract: This disclosure relates to compositions and methods for analyzing a tissue section from a biological sample.Type: GrantFiled: February 10, 2021Date of Patent: December 5, 2023Assignee: 10x Genomics, Inc.Inventor: Felice Alessio Bava
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Patent number: 11828689Abstract: Methods, apparatuses, and systems associated with aerosol collection devices (such as, but not limited to, breath-aerosol collector devices, breathalyzers) are provided. An example aerosol collection device includes a sample transfer adapter configured to receive a sample and a device body connected to the sample transfer adapter. In some examples, the device body defines a flow channel that guides the sample to a filter component, and the filter component contains a buffer solution.Type: GrantFiled: September 1, 2021Date of Patent: November 28, 2023Assignee: Hand Held Products, Inc.Inventors: Adam Dewey McBrady, Moin Shafai, Oscar Ponte Rivas, Aoife Celoria, Philip C. Foster, Dustin Michael Brandt, Giorgio Carlo Isella, Jose Guadalupe Sanchez De La Rosa, Emir Rahislic, Amanda Esther Sall Childers, Gennady Germaine, Thomas Merritt Haggerty
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Patent number: 11815448Abstract: Provided is a means capable of measuring an analyte concentration with high accuracy without requiring fractionation of a biological component. The present invention relates to a method for measuring an analyte concentration in a specimen, including (1) preparing the specimen, (2) mixing a coloring reagent, an oxidoreductase, and a light-scattering adjustment reagent with the specimen to obtain an analysis sample having substantially the same scattered light as the specimen, and (3) measuring the analyte concentration by using the analysis sample.Type: GrantFiled: August 7, 2020Date of Patent: November 14, 2023Assignee: TERUMO KABUSHIKI KAISHAInventors: Fumihiko Chai, Takeyuki Moriuchi
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Patent number: 11802838Abstract: Described herein are methods for quickly measuring properties of grain kernels. The methods allow for a quick, qualitative assessment of high amylose content in the grain kernel. The methods described herein allow for the assessment of high amylose content in wheat in either a laboratory setting or in the field with a minimum of equipment required. The results of these methods may be used to determine if high amylose kernels have been contaminated with normal or low amylose kernels.Type: GrantFiled: March 23, 2021Date of Patent: October 31, 2023Assignee: BAY STATE MILLING COMPANYInventors: Tanya Jeradechachai, Sean Finnie, Alexis Schuko
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Patent number: 11774341Abstract: Quantifying nanobubbles in solution includes combining an indicator with a fluid comprising nanobubbles to yield a first solution, bursting the nanobubbles in the first solution to yield a second solution, and assessing a difference between the first solution and the second solution to yield a concentration of the nanobubbles in the first solution, a concentration of reactive oxygen species in the first solution or the second solution, or both.Type: GrantFiled: September 9, 2021Date of Patent: October 3, 2023Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Paul K. Westerhoff, Shahnawaz Sinha, Yuqiang Bi
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Patent number: 11768216Abstract: A diffusion cell includes: a donor chamber having bottom; a receptor chamber below and in fluid communication with the donor chamber, and having upper and lower ends; a membrane between and in contact with the bottom of the donor chamber and upper end of the receptor chamber, and adapted to diffuse some of the media in a liquid from the donor chamber to the receptor chamber; a conduit having a first port near the lower end of the receptor chamber and a second port above the first port and near the upper end of the receptor chamber; and a bubble trap in fluid communication with the upper end of the receptor chamber and having a third port higher than the second port; wherein circulation of a flow of fluid through the conduit and the receptor chamber removes bubbles from underneath the membrane and transports bubbles to the bubble trap.Type: GrantFiled: November 19, 2020Date of Patent: September 26, 2023Assignee: PermeGear, Inc.Inventor: Andrew Wilt
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Patent number: 11761954Abstract: A method of detecting the presence of an NBOMe in a sample which comprises of contacting the sample with an activated p-quinone such as 2,3,5,6-tetrachloro-1,4-benzoquinone (TCBQ) and an aldehyde, for example acetaldehyde, and optionally a buffer and observing a colour change, which when present, correlates with the presence of an NBOMe. The ingredients may be provided in the form of a kit which can include a colour standard or comparison chart.Type: GrantFiled: August 22, 2019Date of Patent: September 19, 2023Inventors: Shanlin Fu, Laura Jane Clancy, Morgan Philp, Ronald Shimmon