Abstract: Wearable medical devices are provided. An exemplary wearable medical device includes a printed circuit board assembly (PCBA) comprising a dielectric layer having a top surface and conductive features on the top surface of the dielectric layer. Further, the exemplary wearable medical device includes a top housing mounted directly to the top surface of the PCBA. Also, the wearable medical device includes a power source located between the top housing and the PCBA. The top housing and the dielectric layer of the PCBA encapsulates the conductive features and power source and define an outer surface of the wearable medical device.

Abstract: A system for detecting salt ion concentration, comprising a device further comprising a sensor having a carbon printed electrode on a flexible substrate with adhesive on one side (backside) and the circuit electronics to generate pulse signal stimuli and measure salt concentrations to determine hydration level of a person or a living being, wherein the device is a wearable device. The electrode can be made into different shapes changing the area as necessary, since it is a carbon printed electrode and is flexible.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: The present invention discloses a holder carrying thereon a sensor to measure a physiological signal of an analyte in a biological fluid, wherein the sensor has a signal detection end and a signal output end, and the holder includes an implantation hole being a channel for implanting the sensor and containing a part of the sensor, a fixing indentation containing the sensor, a filler disposed in the fixing indentation to retain the sensor in the holder, and a blocking element disposed between the implantation hole and the fixing indentation to hold the sensor in the holder and restrict the filler in the fixing indentation.

Abstract: An oral insert includes at least one pH sensor in electronic communication with a power source and a data transceiver. The pH sensor is exposed to fluids in the patient's mouth and measures the pH of the fluids to determine fluid composition.

Abstract: A system and method for automatically requesting assistance for a user experiencing a medical emergency is disclosed. The system includes a user device with a sensor to detect sensed information. Based on the sensed information the user device can determine if the user is experiencing a medical emergency. The user device can communicate with nearby devices over one or more networks and send information about the medical emergency to the nearby devices. The information can include the type of medical emergency, the location of the user experiencing the medical emergency, and any instructions for providing the user with assistance.

Abstract: An analyte sensor system may include a first communication circuit configured to transmit a wireless signal in a first communication mode and a second communication mode, and a processor, wherein the processor determines whether a first condition is satisfied, the first condition relating to the sensor signal or to communication by the first communication circuit, and shifts the system to a second communication mode responsive to the first condition being satisfied.

Abstract: A method for prolonging a usage lifetime of a micro biosensor to measure a physiological signal associated with an analyte is provided. The micro biosensor includes a working electrode, a counter electrode including silver and a silver halide having an initial amount, and an auxiliary electrode. The method includes cyclic steps of: applying a measurement voltage to drive the working electrode to measure the physiological signal; stopping applying the measurement voltage; and whenever the physiological parameter is obtained, applying a replenishment voltage between the counter electrode and the auxiliary electrode to drive the counter electrode, thereby the silver halide of a replenishment amount being replenished to the counter electrode, wherein a guarding value of a sum of the replenishment amount and the initial amount subtracting a consumption amount is controlled within a range of the initial amount plus or minus a specific value.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: An electronic device includes a sensor configured to acquire a pulse wave of a subject and a controller configured to analyze, based on the pulse wave of the subject acquired by the sensor, the rate of change in the pulse wave at a predetermined time after the point in time exhibiting a peak of the pulse wave and to estimate the blood glucose level of the subject based on the rate of change.

Abstract: Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

Abstract: A wearable blood pressure detecting device is provided. The wearable blood pressure detecting device includes a pulse detecting module, a processing unit, a memory unit, a model selecting unit, and a blood pressure calculating unit. The pulse detecting module is configured to generate a pulse waveform. The processing unit is configured to capture the pulse waveform to generate at least one pulse characteristic value. The memory unit is configured to store at least two blood pressure models corresponding to different pulse characteristic value ranges. The model selecting unit is configured to select a corresponding blood pressure model according to the at least one pulse characteristic value. The blood pressure calculating unit is configured to calculate a blood pressure value by the selected blood pressure model.

Abstract: Devices and methods are described herein for directly and accurately measuring sweat flow rates using miniaturized thermal flow rate sensors. The devices (100, 200, 300, 400, 500, 600, 700, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500) include the flow rate sensors (220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320, 1420) in or adjacent to a microfluidic component (230, 330, 430, 530, 630, 730, 830, 930, 1030, 1130, 1230, 1330, 1430, 1530) of a wearable sweat sensing device. The devices and methods optimize the sensitivity of the flow rate sensors, while minimizing the presence of noise, in order to accurately and directly measure sweat flow rates.

Abstract: Diabetes prediction using glucose measurements and machine learning is described. In one or more implementations, the observation analysis platform includes a machine learning model trained using historical glucose measurements and historical outcome data of a user population to predict a diabetes classification for an individual user. The historical glucose measurements of the user population may be provided by glucose monitoring devices worn by users of the user population, while the historical outcome data includes one or more diagnostic measurements obtained from sources independent of the glucose monitoring devices. Once trained, the machine learning model predicts a diabetes classification for a user based on glucose measurements collected by a wearable glucose monitoring device during an observation period spanning multiple days. The predicted diabetes classification may then be output, such as by generating one or more notifications or user interfaces based on the classification.

Abstract: An apparatus for estimating blood concentration may include an optical sensor configured to emit light towards a skin surface of a user, and detect an optical signal reflected by the skin surface of the user, and a processor configured to select an interval-specific blood concentration estimation model, from among a plurality of interval-specific blood concentration estimation models, based on an interval selection indicator and estimate a blood concentration change or a blood concentration of an analyte using the selected interval-specific blood concentration estimation model and the detected optical signal.

Abstract: A personalized bio-information correcting apparatus includes a communication interface configured to acquire original bio-information value data of a user, and a processor configured to obtain a personalized bio-information guideline, based on a personalized physiological model, identify whether at least one value among the acquired original bio-information value data is an outlier, based on the obtained personalized bio-information guideline, and based on the at least one value among the acquired original bio-information value data being identified to be the outlier, obtain final bio-information value data by correcting the at least one value among the acquired original bio-information value data.

Abstract: A physiological signal monitoring device includes a base, a biosensor mounted to the base and adapted to measure an analytical substance, and a transmitter. The base includes a flexible base body and a first coupling structure. The first coupling structure is disposed on the bottom plate. The transmitter is removably mounted to the base body, and includes a bottom casing and a second coupling structure. The first and second coupling structures are coupled to each other when the transmitter is mounted to the base body, and are uncoupled from each other by the flexibility of the base body when an external force is applied on a periphery of the base body. The first and second coupling structures are disposed to be distal from a periphery cooperatively defined by the base and the transmitter when the first and second coupling structures are coupled to each other.

Abstract: A medical device for transcutaneously inserting an insertable element into a body tissue. The medical device includes an insertable element that has an in vivo distal end for subcutaneous insertion, an ex vivo proximal end, and a pre-bended insertion cannula for subcutaneously inserting the insertable element. The medical device further comprises at least one patch, which is configured to be mounted on the skin of a user. The patch has a patch base and an integrated insertion mechanism for driving the insertion cannula from a storage position within the patch into an inserted position within the body tissue on a curved insertion path.

Abstract: A medical sensor system comprising a sensor implantable under the skin of a user and an on-body module attachable to the skin in the region of the implantable sensor, wherein the on-body module has a self-adhering flexible electronics patch including a first transmitter which is operable to exchange data with the implantable sensor via a short-range wireless connection.

Abstract: An inserter for a medical device, where the inserter includes a housing having a first end with an opening therein, an actuator connected to a first gear, an actuator biasing element, a cam gear assembly including a cam member and a second gear, a cam bridge follower in contact with the cam member, and a first plunger assembly having a first plunger and a first biasing element.