Abstract: Described herein is a prosthetic valve device having an optimized valve component for durability and functionality of the collapsible leaflets. Specially designed commissures contribute to the optimization along with identified parameters. In other embodiments, the invention is a frame formed from a unique cutting pattern.

Abstract: A transcatheter valve prosthesis including a tubular stent, a prosthetic valve component disposed within and secured to the stent, and a centering mechanism coupled to and encircling an outer surface of the tubular stent. The centering mechanism includes a self-expanding centering ring having an expanded diameter in the expanded configuration that is greater than an expanded diameter of the tubular stent in the expanded configuration and a plurality of self-expanding spokes radially extending between the tubular stent and the centering ring. The centering mechanism may include a base ring and/or a skirt. Alternatively, the centering mechanism includes a plurality of self-expanding loops. When each loop is in a delivery configuration the loop has a straightened profile that proximally extends from a proximal end of the tubular stent. When each loop is in an expanded configuration the loop has a U-shaped profile radially spaced apart from the tubular stent.

Abstract: The present invention relates to an implantable apparatus and methods of use thereof for treating congestive heart failure. An apparatus of this invention may be anchored by implantation of a section of the apparatus within in a branch pulmonary artery, for example the left pulmonary artery, which then positions and anchors another section, for example a device frame section of the apparatus within the main pulmonary artery. A medical device may be attached to the anchored device frame.

Abstract: A hemi-arthroplasty bone joint implant has a first part (120) with a stem (111) tor intramedullary implanting into a metacarpal, mid a second part (110) to engage the trapezium is a translational manner, a hemi-arthroplasty articulating coupling (121). This allows multi-axial motion with translational movement of the second part over the trapezium and rotation of the first part (110) about the articulating coupling (121, 103). There is also a converter to convert the implant to a total arthroplasty implant in situ during revision surgery. The second part (110) and the hemi-arthroplasty coupling (100, 123, 121) are removable in situ during revision surgery. The first part (120) has an engagement threaded socket (117) for, after removal of the second part and the hemi-arthroplasty coupling, engaging the replacement coupling (200) and allowing mutual articulation of the first (120) and replacement parts (220). This forms a total arthroplasty joint implant.

Abstract: Disclosed is a patient-specific mandibular implant inserted into a mandibular defect region and a method of manufacturing the same, and more particularly, to a patient-specific mandibular implant inserted into a mandibular defect region, which can be easily and rapidly manufactured using personalized three-dimensional (3D) printing technology for a defect region, can provide an effect of preparing a later step for restoring a tooth in advance, and can be easily manufactured tooth restoration data based on the Korean standard database (DB), and a method of manufacturing the same.

Abstract: An implant includes a primary structural element, and two clips coupled to the primary structural element, on opposite lateral sides of the primary structural element from each other, each of the clips having a first clip element and a second clip element. The implant is transluminally advanced to a heart valve of a subject. The implant is coupled to leaflets of the valve (i) by, for each of the clips, closing the clip around a central part of a respective leaflet of the valve by causing deflection between the first clip element and the second clip element, thereby sandwiching the central part of the respective leaflet between the first clip element and the second clip element, and (ii) such that the leaflets form a double orifice configuration, with the primary structural element disposed between the central parts of the leaflets. Other embodiments are also described.

Abstract: A surgical component, a kit including the surgical component, and a surgical method. The surgical component includes a body portion. The surgical component also includes an elongate stem for inserting into an intramedullary canal of a patient. The elongate stem extends distally from the body portion. The elongate stem has a longitudinal axis; a proximal end; a distal end; and a plurality of splines located on an outer surface of the stem. The splines are circumferentially arranged around the stem. At least some of the splines are tapered such that each tapered spline is narrower at a distal part of that spline than at a part of that spline that is proximal with respect to the distal part. The surgical component further includes an elongate neck portion extending from the body portion at a non-zero angle with respect to the longitudinal axis of the stem.

Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.

Abstract: A prosthetic system includes a prosthetic foot with a foot member defining a first end portion, a second end portion, and an intermediate portion defining a curvature and extending between the first and second end portions. A pump mechanism is coupled to the foot member. The pump mechanism includes a housing defining a cavity, and a membrane situated in the cavity. The pump mechanism is movable between an original configuration and an expanded configuration. A movable member includes a first portion coupled to the membrane and a second portion arranged to slidably engage the foot member. Relative movement between the first and second end portions moves the first portion of the movable member relative to the housing and slides the second portion along a length of the foot member to shift the pump mechanism between the original and expanded configurations.

Abstract: Disclosed herein is a humeral head trial, a system for humeral trialing, and a method for removing a humeral head trial from a humeral stem. The humeral head trial may include a first portion, a second portion, and a post extending from the second portion. The first portion may define a convex articular surface with a movable surface substantially flush with the convex articular surface. The post may define a first length in a first configuration and a second length in a second configuration. The first length may be greater than the second length. The post may change from the first configuration to the second configuration by moving the movable surface with respect to the convex articular surface.

Abstract: The invention relates to an endoprosthesis shaft system for elongate bones, comprising an anchoring part (10) and a shaft (1), which is formed from module elements that can be coupled by means of a plug-in connection (45), wherein a mutual rotation of the elements along the shaft (1) is adjustable and is blocked by means of an anti-rotation mechanism. In order to adjust the rotation, a rotation piece (5) is provided as a further module element, which has a self-contained rotation adjustment device (6) and a clamping device (7) as a mechanism for blocking the rotation. The rotation piece (5) comprises two end faces for the plug-in connection (45) and a sleeve (77). The invention provides, with the rotation piece, a particular module element for the shaft, which as a structural unit allows both an adjustment of the rotation and a blocking against undesired rotation in a self-contained unit.

Abstract: An inserter includes a first end, a second end, and a body extending between the first end and the second end. A first impacting surface is disposed at the first end, and a second impacting surface is disposed adjacent to the second end. An interface disposed at the second end and is configured to engage an implant. The first impacting surface is configured to direct a first impacting force along the body of the inserter in a first direction, and the second impacting surface is configured to direct a second impacting force along the body in a second direction that is different from the first direction. Methods of use also are disclosed.

Abstract: Techniques for implantable orthopedic pain management devices are disclosed, including incising an opening in a synovial capsule substantially surrounding a joint, using a first tool to form an enlarged opening in the synovial capsule, determining whether to modify the joint, the joint being modified using a second tool if a bone structure coupled to one or more bones is found within the joint and the bone structure is configured to limit articulation of the one or more bones when an implantable device is inserted into the synovial capsule and the joint, and inserting the implantable device into the synovial capsule through the enlarged opening, the implantable device being inserted into the joint using a third tool.

Abstract: The invention relates generally to generation of biomimetic scaffolds for bone tissue engineering and, more particularly, to multi-level lamellar structures having rotated or alternated plywood designs to mimic natural bone tissue. The invention also includes methods of preparing and applying the scaffolds to treat bone tissue defects. The biomimetic scaffold includes a lamellar structure having multiple lamellae and each lamella has a plurality of layers stacked parallel to one another. The lamellae and/or the plurality of layers is rotated at varying angles based on the design parameters from specific tissue structural imaging data of natural bone tissue, to achieve an overall trend in orientation to mimic the rotated lamellar plywood structure of the naturally occurring bone tissue.

Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.

Abstract: The present invention is directed generally to (1) an articulating junction, and articulation method thereof, wherein articulation is facilitated by a plurality of magnetic particles; (2) an articulating junction, and articulation method thereof, wherein the stability and fluidity of the junction is based, at least in part, on the magnetic field(s) of the plurality of magnetic particles; and (3) reducing the resistance to articulation and/or increasing the structural integrity and support, of the articulating junction, via electro-magnetism. Further, the present invention is directed generally to the synergistic combination of magnetic particles and preferred bio-implant-materials and additive-manufacturing methods along with Baker correlation codes. Further, the present invention is directed to an artificial joint for implantation into a living body and methods for constructing such an artificial joint.

Abstract: A prosthesis for at least a portion of a bone, in particular a bone or portion thereof to which, in the natural condition, a tendon of a muscle is attached, wherein the prosthesis is manufactured of a metal or an alloy thereof and is provided with at least one area situated in the surface of the prosthesis that faces outward once the prosthesis has been placed in the body, the area being formed by a layer provided with open spaces that are connected to each other, wherein the open spaces are dimensioned for allowing the growth of bone tissue therein.

Abstract: A hemi-prosthesis implant comprises a replacement-joint part with an articulation surface for tribological pairing with a joint surface of a natural joint counterpart. The articulation surface is embodied with a coating applied on a substrate. The substrate provides a relief for the adhesion of the coating. The relief may comprise one or more of a plurality of grooves, a plurality of teeth, a ribbing, and a roughened surface. The relief may be embodied entirely or partially outside the articulation surface. The replacement joint part may optionally comprise a ventilation feature, and the articulation surface may be formed by injection molding on the substrate. The hemi-prosthesis implant may be part of an implant set that includes both a hemi-prosthesis implant and a total prosthesis implant, either of which can be chosen intraoperatively.

Abstract: A bone fusion device provides stability to bones during a bone fusion period. The bones include, for example, the vertebrae of a spinal column. The bone fusion device comprises one or more extendable tabs attached to the bone fusion device by associated rotating means. The bone fusion device is preferably inserted by using an arthroscopic surgical procedure. During arthroscopic insertion of the device, the tabs are pre-configured for compactness. In this compact configuration, the tabs are preferably deposed along and/or within an exterior surface of the bone fusion device. After the bone fusion device has been positioned between the bones, one or more tab(s) are extended. In the preferred embodiment, the position of each tab is related to a positioning element and extending blocks. Typically, the tabs advantageously position and brace the bone fusion device in the confined space between the bones until the bones have fused.

Abstract: Multi-hooded enarthrodial joint implant has a hard substance articulating cup including a hard substance head-receiving cup having an articular surface upon which a head of a joint can articulate, and which, in general, has a margin generally about a hemisphere more or less and at least two hoods that are marginally extended continuations of superior one-half or so of cup containment of a sufficient magnitude to reduce an overall dimension of socket outlet to less than a hemisphere, which can embrace and contain the head. The head is made of a hard substance and has a truncated generally circular cross section, a truncated surface with a feature for attachment of the stem, and an opposing articular surface for articulation against the articular surface of the ceramic head-receiving cup. As an ensemble, the cup is combined with the head, typically with a stem, for a total joint implant. The hard substance may be, for example, a composite substance, a metal or a metal alloy.