Patents Examined by Amber R Stiles
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Patent number: 11969569Abstract: A microneedle cartridge according to the present disclosure includes a disk-shaped cartridge main body including a rotational force receiver configured to receive a rotational force from a microneedle applicator, a plurality of first through-holes radially disposed about the center of the cartridge main body, a plurality of microneedle bases each disposed in one of the first through-holes and having one or more microneedles disposed on a lower surface, a maintaining member configured to maintain the microneedle base inside the through-hole, and a second through-hole through which a pressing portion of the microneedle applicator passes when operating to seal the microneedle applicator, wherein the microneedle base is configured to be movable between a first position at which the microneedle base is not pressed by the pressing portion and a second position at which the microneedle base is maximally pressed by the pressing portion.Type: GrantFiled: December 9, 2021Date of Patent: April 30, 2024Assignee: JUBILEE BIOTECH CO., LTD.Inventors: Sung Kyoung Lee, Goonghyun Han
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Patent number: 11951272Abstract: A cryo formulation-based microneedle device for ocular delivery of bioactive therapeutic agents. The microneedle device includes: one or more microneedle patches each including an array of miniaturized needles, wherein each miniaturized needle defining a base end and a tip; and a substrate to which the base end of the array of miniaturized needles is attached or integrated thereto; wherein the microneedle patch is in a cryo status; wherein each of the one or more microneedle patch is adapted to be applied on cornea of an eye, in which the miniaturized needles penetrates into the eye; and wherein the miniaturized needles is further arranged to melt so as to release one or more bioactive therapeutic agents into the eye to achieve a targeted therapeutic effect.Type: GrantFiled: July 27, 2021Date of Patent: April 9, 2024Assignee: City University of Hong KongInventors: Chenjie Xu, Hao Chang
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Patent number: 11944796Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.Type: GrantFiled: August 24, 2020Date of Patent: April 2, 2024Assignee: Sanofi-Aventis Deutschland GMBHInventors: Maurice Toporek, Matthias Felber, Christoph Matthias Gugl, Marcus-Meinolf Dittrich, Christian Nessel, Stephan Riedel, Armin Koller, Alexander Heinrich, Florian Eberli, Philipp Muller, Sven Zwicker
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Patent number: 11931537Abstract: An allergen-loadable microneedle cartridge is disclosed. The cartridge includes at least one substrate, a plurality of microneedles in a microneedle layout protruding from at least one substrate, and fillable allergen sites corresponding to the microneedle layout. The fillable allergen sites and microneedle layout are configured such that the microneedles can penetrate subject skin and deliver pharmacologically active doses of allergens in a minimally invasive process. A planar allergen filling system for loading the allergen-loadable microneedle cartridges is also disclosed. The system has a loading section with spaced-apart allergen loading sites that correspond to the microneedle layout of the microneedle cartridge. Filling wells having allergen deposition areas larger than the allergen loading sites transfer deposited allergen to the allergen loading sites through capillary channels.Type: GrantFiled: October 5, 2020Date of Patent: March 19, 2024Assignee: SensiVida Medical Technologies INC.Inventors: Jose M. Mir, John P. Spoonhower
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Patent number: 11925450Abstract: Embodiments relate to guiding medical care based on detected gastric function. For example, gastric acid stimulant or suppressant is administered, and then a change in the gastric juice H+ concentration is measured. This change is compared to a guidance H+ concentration differential indicative of relatively healthy gastric function. Medical care is guided based on a relatively healthy gastric function if the measured H+ concentration differential is equal to or exceeds the guidance H+ concentration differential, while medical care is guided based on a relatively unhealthy gastric function if the measured H+ concentration differential is less than the guidance H+ concentration differential. Disclosed embodiments implementing this procedure include, but are not limited to, methods, apparatus, processors, computer programs, and computer-readable mediums.Type: GrantFiled: May 8, 2020Date of Patent: March 12, 2024Assignee: Gravitas Medical, Inc.Inventor: Elliott Bennett-Guerrero
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Patent number: 11911581Abstract: Balloon based therapy devices for treatment of diseased vessels are described. The devices are adapted for active aspiration of a closure zone prior to delivery of a closure agent. The devices may be used for treatment of diseased veins in the lower limbs and pelvis.Type: GrantFiled: July 28, 2023Date of Patent: February 27, 2024Assignee: Controlled Delivery Systems, Inc.Inventor: Ali Golshan
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Patent number: 11911070Abstract: A seal assembly for use with an access apparatus includes an integral filter and evacuation port for filtering of fluids, e.g., smoke, from an operating site and removing contaminants and/or odor from the fluids for release of the filtered fluids into the ambient atmosphere. The seal assembly may be a separate subassembly or component which is releasably couplable to the access apparatus or may be integral with the access apparatus. The seal assembly defines its own flow path independent of the insufflation mechanism of the cannula assembly, and is capable of filtering fluids even in the presence of a surgical object positioned within the cannula assembly.Type: GrantFiled: December 2, 2020Date of Patent: February 27, 2024Assignee: Covidien LPInventors: Henry Holsten, Kenneth Horton
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Patent number: 11911501Abstract: A biocompatible resin composition that is used in the manufacture of a dissolvable microneedle that is used for the transdermal delivery of one or more active pharmaceutical ingredients to a subject. The biocompatible resin composition includes lithium phenyl-2,4,6-trimethylbenzoylphospinate, water, and poly(ethylene glycol) diacrylate (molecular weight 550), and may include methacrylated hyaluronic acid, that is capable of forming a structurally stable microneedle patch. The microneedle patch is formulated with the biocompatible resin composition using a continuous, one-step process utilizing additive manufacturing. Once manufactured, the microneedle patches are formulated to adhere to an outer layer of a subject's skin. Once administered to the subject, the microneedle compositions create microscopic pathways into the subject's subdermal layers to deliver one or more active agents to the subject, such as to the subject's bloodstream.Type: GrantFiled: August 4, 2021Date of Patent: February 27, 2024Assignee: Florida A&M UniversityInventors: Mandip Sachdeva, Arvind Bagde, Satyanarayan Dev
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Patent number: 11904126Abstract: A cryo formulation-based microneedle device for transdermal delivery of bioactive therapeutic agents. The microneedle device includes: one or more microneedle patches each including an array of miniaturized needles, wherein each miniaturized needle defining a base end and a tip; and a substrate to which the base end of the array of miniaturized needles is attached or integrated thereto; wherein the microneedle patch is in a cryo status; wherein each of the one or more microneedle patch is adapted to be applied on a skin surface, in which the miniaturized needles penetrates into skin; wherein the miniaturized needles is further arranged to melt so as to release one or more bioactive therapeutic agents into the skin to achieve a targeted therapeutic effect; and wherein the bioactive therapeutic agents includes protein and/or antigens.Type: GrantFiled: July 27, 2021Date of Patent: February 20, 2024Assignee: City University of Hong KongInventors: Chenjie Xu, Hao Chang
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Patent number: 11904127Abstract: An applicator for an analyte monitoring device may include an actuatable housing having a body defining a cavity therein and having a distal opening and a side opening. A cuff and a shuttle are received within the cavity and are separately translatable relative to the housing body. A base may removable engage the housing body at the distal opening. The housing body, the cuff, the shuttle, and/or the base may be engaged with one another with one or more releasable coupling features. The base may be removed from an engagement with the housing body, causing the cuff and the shuttle to be aligned and positioned in a configuration in which the analyte monitoring device, held by the shuttle, is ready for insertion into the skin.Type: GrantFiled: April 25, 2023Date of Patent: February 20, 2024Assignee: Biolinq IncorporatedInventors: George Albert Mansfield, III, David Michael Morelock, Mark Christopher Brister, Nathan Thomas Balcom, Joshua David Doan, Joshua Andrew Warner
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Patent number: 11906719Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a formulation or implant device to a target location under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: GrantFiled: January 22, 2021Date of Patent: February 20, 2024Assignee: Spiral Therapeutics Inc.Inventors: Eugene de Juan, Hugo Peris, Signe Erickson, Vrad Levering
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Patent number: 11896794Abstract: A medical device accessory comprising an interface configured to connect the medical device accessory with a medical device for administration of a medical treatment using the medical device and the medical device accessory, a plurality of electrical contacts proximate the interface, the electrical contacts comprising a lead electrical contact adapted to receive an voltage from a power source associated with the medical device and one or more identifying electrical contacts, and at least one conductor providing an electrical connection between the lead electrical contact and the one or more identifying electrical contacts. An arrangement of the one or more identifying electrical contacts connected to the lead electrical contact identifies a characteristic of the medical device accessory.Type: GrantFiled: September 21, 2020Date of Patent: February 13, 2024Assignee: Northgate Technologies Inc.Inventors: Robert Mantell, Chip Curtis, Steven Weaver, Eric Andersen
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Patent number: 11883635Abstract: A system for injecting includes a syringe body, a syringe interior, a syringe flange, and a stopper member and an injectable fluid disposed in the syringe interior. The system also includes a plunger member coupled to the stopper member. The system further includes a finger flange removably coupled to the syringe flange, the finger flange defining a pair of side openings and a pair of bumps adjacent respective side openings. Moreover, the system also includes a swing spacer rotatably coupled to the finger flange, the swing spacer defining a pair of arms, a pair of pivot pins, two pairs of slots, and a pair of indentations. The swing spacer is configured to define a distance of movement of the plunger member relative to the syringe body along a longitudinal axis of the syringe body, thereby defining a dose of the injectable fluid.Type: GrantFiled: June 17, 2021Date of Patent: January 30, 2024Assignee: Credence MedSystemsInventor: Alan E. Shluzas
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Patent number: 11883576Abstract: The invention relates to systems and methods for making intracycle adjustments to an osmotic agent concentration of peritoneal dialysate inside the peritoneal cavity of a patient. The systems and methods include osmotic agent sources, flow paths, and processors to adjust the osmotic agent concentration of dialysate in the peritoneal cavity of the patient. The method can include infusing peritoneal dialysate containing an osmotic agent into the peritoneal cavity of a patient; monitoring one or more patient parameters; and adjusting the osmotic agent concentration of the peritoneal dialysate in the peritoneal cavity of the patient by infusing a concentrated osmotic agent solution or by infusing sterile fluid into the peritoneal cavity of the patient using an on-line peritoneal dialysis machine. The system can include a peritoneal dialysis cycler.Type: GrantFiled: September 17, 2020Date of Patent: January 30, 2024Assignee: Mozarc Medical US LLCInventors: Martin T. Gerber, Christopher M. Hobot
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Patent number: 11887716Abstract: A method includes receiving, by a master infusion device from a server, at least one fluid delivery protocol. The fluid delivery protocol includes one or more parameters for delivering a fluid to a user. The method also includes configuring, by the master infusion device, a first slave infusion pump with a first fluid delivery protocol of the at least one fluid delivery protocol. The method further includes configuring, by the master infusion device, a second slave infusion pump with a second fluid delivery protocol of the at least one fluid delivery protocol. The method also includes delivering, by the first slave infusion pump and based on the first fluid delivery protocol, the fluid to the user. Related methods and articles of manufacture, including apparatuses and computer program products, are also disclosed.Type: GrantFiled: April 9, 2021Date of Patent: January 30, 2024Assignee: CareFusion 303, Inc.Inventors: Keith Mooney, Kevin O'Brien, Christopher Coleman, Dara George, Ehab Azab
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Patent number: 11871934Abstract: Catheters are described that have improved flow characteristics that may be particularly helpful when delivering embolic agents within a blood vessel. One catheter includes a fluid flow modifier that is configured to create laminar fluid flow out of a distal end of the catheter to help reduce turbulence and achieve predictable fluid movement. Another catheter includes scavenging ports that are configured to suction in embolic agents that have refluxed proximally back from a distal end of the catheter.Type: GrantFiled: September 28, 2021Date of Patent: January 16, 2024Assignee: MicroVention, Inc.Inventors: George Stern, Vladimir Satchouk
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Patent number: 11872354Abstract: The designs herein can be for a flexible and kink-resistant catheter with a support tube which can be radially expanded to enable it to be slid over an inner liner on a mandrel during assembly. The designs are flexible enough to allow the catheter to access remote vessel occlusions but also benefit from good compressive and tensile stiffness. The designs can have a laser cut frame with interlocking structure of circumferentially discontinuous rib struts. The discontinuities can be aligned to form at least one continuous axial seam which is separable to allow for the radial expansion during manufacturing. A series of polymeric outer jackets can coat or encapsulate the struts of the frame, giving variable stiffness and preventing disengagement of the interlocking structure while the catheter is pushed through tortuous anatomy.Type: GrantFiled: February 24, 2021Date of Patent: January 16, 2024Assignee: NEURAVI LIMITEDInventor: David Vale
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Patent number: 11864953Abstract: A smoke evacuating tissue guard includes a tubular body defining a longitudinally-extending passageway, a collar coupled to a proximal end portion of the tubular body, and an outlet coupled to the collar and in fluid communication with an annular channel defined through the collar. Upon application of suction through the smoke evacuating tissue guard, the smoke evacuating tissue guard establishes a fluid path extending from the passageway of the tubular body and into the annular channel of the collar via an annular gap defined between the tubular body and the collar.Type: GrantFiled: January 23, 2020Date of Patent: January 9, 2024Assignee: COVIDIEN LPInventors: Jacob C. Baril, Matthew A. Dinino, Saumya Banerjee
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Patent number: 11857767Abstract: An injector includes a body, an injection needle movably mounted to the body and a pathway within the body sized for receiving either of a first cartridge or a differently dimensioned second cartridge therein. The pathway includes a coupler mounted at a distal end that is engageable with the first cartridge or the second cartridge for to fluidly connect with the injection needle. At least two adapter collars are mounted within the pathway. A first adapter collar is configured to receive either one of the two cartridges therethrough upon insertion into the pathway, and configured to engage a portion of the first cartridge to stabilize the first cartridge within the pathway. A second adapter collar is also configured to receive either one of the two cartridges therethrough upon insertion into the pathway, but configured to engage a portion of the second cartridge to stabilize the second cartridge within the pathway.Type: GrantFiled: December 20, 2018Date of Patent: January 2, 2024Assignee: West Pharma. Services IL, LTD.Inventors: Yossi Bar-El, Igor Isakov, Lior Barchen
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Patent number: 11857719Abstract: In one embodiment, a filter assembly for use in an insufflation system is described. The filter assembly comprises: a filter medium operative to filter medical gases; a housing comprising an inlet, an outlet and the filter medium, the housing defining a gases flow path through the filter medium between the inlet and the outlet; and at least one heating element being positioned in the housing and being configured to heat the filter medium; and wherein, the at least one heating element is spaced apart from the filter medium and from an inner surface of the housing.Type: GrantFiled: December 8, 2017Date of Patent: January 2, 2024Assignee: FISHER & PAYKEL HEALTHCARE LIMITEDInventors: Richard John Boyes, Christian Francis Fischer, Ali Ghalib Abdul Rahman Ghalib, Jessica Kristen Sloane, Monika Baumann, Bernard Tsz Lun Ip