Patents Examined by Andrew Bowman
  • Process for dry powder formulations
    Patent number: 9259376
    Abstract: The present invention relates to a process developed for production of a dry powder medicament used in respiratory tract diseases such as asthma and COPD.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: February 16, 2016
    Assignee: Sima Patent ve Lisanslama Hizmetleri Ltd. Sti.
    Inventor: Mahmut Bilgic
  • Surface coating processes and uses of same
    Patent number: 9254550
    Abstract: The present application relates to processes for coating surfaces and provides a method of forming a coating on a surface. The method involves bombarding a surface with particles having sufficient energy to remove surface material. At the same time an aerosol is delivered to the surface. The cooperative action of the particles impinging on the surface and the presence of the aerosol contribute to the formation of a coating on the surface.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: February 9, 2016
    Assignee: HKPB Scientific Limited
    Inventors: Donncha Haverty, Brendan Kennedy
  • Nanoparticle coating of surfaces
    Patent number: 9248217
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: February 2, 2016
    Assignee: Nanocopocia, LLC
    Inventors: Robert A. Hoerr, John V. Carlson
  • Method for producing implants with an ultrahydrophilic surface
    Patent number: 9242029
    Abstract: The present invention concerns a process for the production of implants with an ultrahydrophilic surface as well as the implants produced in that way and also processes for the production of loaded, so-called bioactive implant surfaces of metallic or ceramic materials, which are used for implants such as artificial bones, joints, dental implants or also very small implants, for example what are referred to as stents, as well as implants which are further produced in accordance with the processes and which as so-called “delivery devices” allow controlled liberation, for example by way of dissociation, of the bioactive molecules from the implant materials.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: January 26, 2016
    Assignee: Herbert Jennissen
    Inventors: Herbert Jennissen, Steffen Lüers, Markus Laub
  • Coating system, articles and assembly using the same and methods of reducing sticktion
    Patent number: 9234118
    Abstract: The present invention provides a coating system for an article including a first component having a surface in frictional engagement with a surface of a second component, wherein at least a portion of at least one surface of the component(s) is coated with a coating prepared from a composition including a first, curable organopolysiloxane comprising at least two alkenyl groups; and a second, curable organopolysiloxane comprising at least two polar groups, the second organopolysiloxane being different from the first organopolysiloxane, which can provide low breakloose force when used in syringe assemblies.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: January 12, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Xia Zhao, Yongming Liu
  • Artificial hair filament having antibacterial and antifungal properties, method and device for preparing the same
    Patent number: 9233392
    Abstract: An artificial hair filament having a core/sheath structure is provided. The artificial hair filament has excellent antibacterial and antifungal effects since antibacterial and antifungal nanoparticles are included in the sheath structure of the artificial hair filament. Here, the antibacterial and antifungal effects can last for a long period of time. A contact-type drug-treating roller and an ultrasonic spraying machine can be used to provide the artificial hair filament with the antibacterial and antifungal effects. In the artificial hair filament, the sheath structure is formed so that the sheath structure occupies 5 to 20% of an entire filament diameter, thereby exhibiting desirable antibacterial and antifungal effects. Therefore, degradation of the antibacterial properties and antifungal properties with time can be prevented.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: January 12, 2016
    Assignees: Selim Fiber Co., Ltd.
    Inventor: Sang Soon Han
  • Synthetic coating for cell culture
    Patent number: 9222000
    Abstract: A method for coating a surface of a cell culture article includes dissolving a polymer having a covalently attached polypeptide in an aqueous solution to produce a polymer solution. The polymer is formed from monomers selected to form a polymer having a linear backbone, wherein the polymer is crosslink free. The weight percentage of the polypeptide relative to the polymer conjugated to the polypeptide is sufficiently high to render the polymer conjugated to the polypeptide water soluble. The aqueous solution is substantially free of organic solvents. The method further includes (i) disposing the polymer solution on the surface of the cell culture article to produce a coated article; and (ii) subjecting the coated article to sufficient heat or electromagnetic radiation to attach the polymer conjugated to a polypeptide to the surface of the cell culture article.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: December 29, 2015
    Assignee: Corning Incorporated
    Inventors: Anthony Glenn Frutos, David Henry, Corinne Walerack
  • Method and device for loading medical appliance with medicaments and/or polymers
    Patent number: 9205180
    Abstract: A method and a device for loading a medical appliance with a medicament and/or polymer includes capturing images of a plurality of grooves or holes of the medical appliance using an image capturing device; performing digital image processing on the image of each of the grooves or holes to obtain a pattern of each of the grooves or holes; calculating a central position of the pattern of each of the grooves or holes, and determining a loading position of each of the grooves or holes based on the central position; and adjusting a relative position between a loading device and the medical appliance to align an outlet of the loading device with the loading position of the medical appliance, and loading each of the grooves or holes with the medicament and/or polymer. The method and device can load the medical appliance with the medicament and/or polymer fast and efficiently.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: December 8, 2015
    Assignee: SHANGHAI MICROPORT MEDICAL (GROUP) CO., LTD.
    Inventors: Jie Zhang, Bo Yi, Changsheng Wu, Zhirong Tang, Qiyi Luo
  • Drug-eluting coatings applied to medical devices by spraying and drying to remove solvent
    Patent number: 9204980
    Abstract: A coating device for coating a medical device with a drug-eluting material uses an in-process drying station between coats to improve a drug release profile. The drying station includes a heat nozzle configured for applying a uniform drying gas. A coating process using the dryer includes a closed-loop control for the gas between drying steps and an improved nozzle for producing more consistent spray patterns.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: December 8, 2015
    Assignee: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: Matthew J. Gillick, John E. Papp, Kevin Seiki, Hung Nguyen
  • Heating method and heating apparatus
    Patent number: 9205449
    Abstract: A method of manufacturing an elongated medical body coated with a fluororesin involves applying the fluororesin to the outer surface of an elongated body having a metallic substrate, and heating the elongated body with the fluororesin applied through operation of a heat source, while cutting off direct radiation of infrared rays generated from the heat source.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: December 8, 2015
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Yuuki Yoshifusa, Yutaka Itou, Hiraku Murayama
  • Modifying polymer properties with penetrants in the fabrication of bioresorbable scaffolds
    Patent number: 9205456
    Abstract: Methods of fabricating a bioresorbable polymer scaffold are disclosed including a step of inducing crystallization in a bioresorbable polymer construct through exposure to a liquid penetrant.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: December 8, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael Trollsas, John Stankus, Michael H. Ngo, Wen Chung Tsai, Thierry Glauser
  • Atmospheric plasma coating for ophthalmic devices
    Patent number: 9156213
    Abstract: The invention provides a method of coating and thereby affecting the surface properties of a substrate such as a contact lens or other ophthalmic device. The method comprises the steps of generating an atmospheric plasma flow from a working gas and controlling the continuity of the atmospheric plasma flow with a power generator, and, introducing the atmospheric plasma flow to a substrate surface.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: October 13, 2015
    Assignee: Novartis AG
    Inventors: Yongxing Qiu, John Dallas Pruitt, Chandana Kolluru, Maria A. Dunkle, Yasuo Matsuzawa
  • Medical device coating apparatus and methods of use
    Patent number: 9132446
    Abstract: Apparatus and methods are configured to coat a medical device, such as a stent, with a beneficial medicinal agent using one or more liquid feeds and one or more micromist nozzles. In one implementation, an agent coating rig includes a vertical adjustment means, a rotation means, and a traverse adjustment means for moving a medical device along virtually any point on an x or y axis. In additional or alternative implementations, the agent coating rig can further include a secondary horizontal adjustment means that allows adjustment along virtually any point on a z axis. Furthermore, methods and apparatus are provided for distributing the beneficial agent on the medical device, including delivering the beneficial agent efficiently over time.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: September 15, 2015
    Assignee: ABBOTT LABORATORIES
    Inventors: Isaac Plans, David O'Neill, Matthew Coates, Javier P. Moreno
  • Method for modifying non-woven chitosan fabric
    Patent number: 9119894
    Abstract: A method for modifying a non-woven fabric of chitosan fiber. The method includes: adding succinic anhydride to an industrial alcohol, ethanol, or acetone; controlling the mass ratio of succinic anhydride to the non-woven fabric at between 0.8 and 3.5; and stirring the resulting mixture until the succinic anhydride has dissolved to yield a succinic anhydride mixed solution; placing the succinic anhydride mixed solution in a constant temperature shaking bath; heating the succinic anhydride mixed solution; adding an HCl solution to the succinic anhydride mixed solution, and stirring evenly to yield a HCl mixed solution; immersing the non-woven fabric in the HCl mixed solution; dehydrating; immersing the non-woven fabric in ethanol or acetone; immersing the non-woven fabric in anhydrous ethanol or pure acetone; dehydrating; and air drying the non-woven fabric.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: September 1, 2015
    Assignee: QINGDAO JIFA NEW MATERIAL CO., LTD.
    Inventors: Yuhua Huang, Weidong Yang, Hongjun Yi
  • Solventless mixing process for coating pharmaceutical ingredients
    Patent number: 9107851
    Abstract: The present invention is a solventless method of producing polymer coated active pharmaceutical ingredient that is taste-masked and may be released in relatively short time. It employs high energy vibrations or acoustic mixing of API particles, water soluble coating material particles and hydrophobic polymer particles, with or without use of other pharmaceutically relevant powders as media. Additionally the method is capable of producing individually coated drug particles without agglomeration or the long drying times associated with solvent based coating methods.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: August 18, 2015
    Assignee: New Jersey Institute of Technology
    Inventors: Rajesh N. Dave, Daniel To, Maxx Capece
  • Nanoparticle coating of surfaces
    Patent number: 9108217
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: August 18, 2015
    Assignee: Nanocopoeia, Inc.
    Inventors: Robert A. Hoerr, John V. Carlson
  • Method for producing spherical base granules comprising hardly water-soluble drug
    Patent number: 9095512
    Abstract: Spherical base granules comprising a hardly water-soluble drug and suited for film coating thereon are produced by layering spherical core particles with a drug-containing layering liquid comprising both micronized microcrystalline cellulose and an emulsifier therein and therefore having improved suspension stability.
    Type: Grant
    Filed: August 9, 2007
    Date of Patent: August 4, 2015
    Assignee: ASAHI KASEI CHEMICALS CORPORATION
    Inventors: Yoshihito Yaginuma, Rika Matsumoto
  • Coating method and coating device
    Patent number: 9078959
    Abstract: A device for coating at least regions of a medical implant includes an elastically deformable transfer means having a liquid that contains at least one pharmaceutically active substance. The liquid can be transferred to the medical implant when the transfer means is contacted with a surface of the medical implant.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 14, 2015
    Assignee: Heraeus Medical GmbH
    Inventors: Sebastian Vogt, Klaus-Dieter Kühn
  • Methods to improve adhesion of polymer coatings over stents
    Patent number: 9061091
    Abstract: Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: June 23, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing Wang, Daniel A. Castro, Stephen D. Pacetti
  • Medical device with crystalline drug coating
    Patent number: 9056152
    Abstract: A medical device having a polymer-free outer surface layer comprising a crystalline drug selected from the group consisting of everolimus, tacrolimus, sirolimus, zotarolimus, biolimus, and rapamycin. The device may be produced by a method comprising the steps of providing a medical device; applying a solution of the drug to said portion of the outer surface to form a coating of amorphous drug; and vapor annealing the drug with a solvent vapor to form crystalline drug; wherein a seed layer of a crystalline form of said drug having a maximum particle size of about 10 ?m or less is applied to at least said portion of the outer surface of the device before or after applying the drug solution, but before vapor annealing the amorphous coating.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: June 16, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Steve Kangas, James Feng, Yen-Lane Chen, Maggie Zeng