Abstract: Universal endovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.

Abstract: The present disclosure relates to a graft material including a self-healing polymer layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment, the implantable medical device is a stent graft.

Abstract: This disclosure relates to orthopaedic implants and methods for repairing bone defects and restoring functionality to a joint. The implants disclosed herein include augment geometries that may approximate a surface contour or bone void along a surgical site and include patterns of peripheral apertures that may be utilized for improved fixation of the implants at the surgical site.

Abstract: A stemless humeral shoulder assembly having a base member and an anchor advanceable into the base member. The base member can include a distal end that can be embedded in bone and a proximal end that can be disposed at a bone surface. The base member can also have a plurality of spaced apart arms projecting from the proximal end to the distal end. The anchor can project circumferentially into the arms and into a space between the arms. When the anchor is advanced into the base member, the anchor can be exposed between the arms. A recess can project distally from a proximal end of the anchor to within the base member. The recess can receive a mounting member of an anatomical or reverse joint interface.

Abstract: Systems, devices and methods related to various heart valve implants and for delivery of those implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve. The implants include a re-sizable frame having angled struts. The implant is secured to tissue with anchors that can rotate without axial advancement to engage tissue while drawing the implant closer to the tissue. Collars are used to decrease the angle between struts of a frame to contract the implant. The implants can include a rotatable shaft, such as a threaded shaft, located internally to an axially translatable collar. Rotation of the shaft transmits force to the collar to cause the collar to translate axially, closing the angle of adjacent struts and decreasing the width of the implant and thus of the annulus. The implants can be delivered, secured and contracted via a catheter. The implants are repositionable and retrievable via catheter.

Abstract: According to one aspect of the disclosure, a glenoid implant for replacing a native glenoid includes an articulating surface configured to articulate with respect to a humeral head. A bone-facing surface may be opposite the articulating surface, the bone-facing surface having a first area configured to contact a paleoglenoid of the native glenoid. An augment portion may be coupled to the bone-facing surface, the augment portion being configured to contact a neoglenoid of the native glenoid. The augment portion may be transitionable between a first configuration in which the augment portion has a first convexity and a second configuration in which the augment portion has a second convexity different than the first convexity.

Abstract: Minimally invasive methods and devices for introducing a spinal fixation element into a surgical site in a patient's spinal column are provided. In general, the method involves advancing a spinal fixation element in a first, lengthwise orientation along a pathway extending from a minimally invasive percutaneous incision to a spinal anchor site. As the spinal fixation element approaches the spinal anchor site, the fixation element can be manipulated to extend in a second orientation, which is preferably substantially transverse to the first orientation, to position the fixation element in relation to one or more spinal anchors.

Abstract: An intraluminal support structure having a delivery configuration that is a crimped open configuration to increase flexibility while maneuvering in the anatomy and having a small scarring signature.

Abstract: Devices and associated methods are disclosed for improving the fixation of the stent graft to the wall of the abdominal aortic neck and to increase the tightness of the aneurysmal sac from the main lumen of the abdominal aorta. Particular embodiments are directed to a bifurcated stent graft system for the treatment of the abdominal aortic aneurysm, which includes an aortic bifurcation segment, two iliac segments and an additional inner segment. The aortic bifurcation segment contains a main tubular body with branched legs at the distal end made of biocompatible fabric material attached to and supported by stents. The proximal end of the aortic bifurcation segment is configured to engage with a part of the aorta, without aneurysmal dilatation, proximal to the renal arteries and contains only a metal expandable frame (for example, a stent), without fabric material, but with fixing pins for engagement with the aortic wall proximal to the renal arteries.

Abstract: A system for shoulder repair includes a prosthetic stemless shoulder implant including a base member extending along a longitudinal axis from a first side to a second side. The second side adapted to engage bone of a patient. The base member defines a hole that extends along the longitudinal axis and through the second side of the base member for receiving a flexible member therethrough. The system includes a fixation construct including a first fixation device and a second fixation device, the first and second fixation devices connected by the flexible member. While the first fixation device is positioned outside of the second side of the base member and the second fixation device is positioned within the base member, the flexible member is adapted to tension the first fixation device with respect to the second fixation device.

Abstract: A malleable demineralized bone composition consists of cortical bone made from a first portion and a second portion. The first portion and second portion of cortical bone is made from cut pieces freeze dried then ground into particles and demineralized then freeze-dried. A volume of the second portion is placed in a solution of sterile water to create a mixture, the water volume being seven times the volume of the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, and the first portion is mixed with the gelatin to form a malleable putty or paste.

Abstract: A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed on an outer surface of the tubular body, and the fabric having an inflow end and an outflow end. Furthermore, the outflow end of the fabric being directly connected to an outer circumferential edge of the valve.

Abstract: An ankle prosthesis has a tibial component configured for attachment to a tibia of a person, and a talar component. The talar component has a first surface configured for facing the tibial component and a second surface configured for facing a talus of the person. The second surface has first and second arms attached to it, for pivoting or flexing outwardly in medial and lateral directions, respectively, to engage side surfaces of a previously formed slot in the talus.

Abstract: The present invention relates to a modular knee prosthesis assembly kit for replacement of resected articular surfaces of a distal femur of a first patient side. The kit comprises at least one bi-condylar component sized and shaped to substantially replace resected posterior and distal condylar bone portions; and at least a first trochlear groove component and a second trochlear groove component, each sized and shaped to replace a resected trochlear groove bone portion. The first trochlear groove component comprises a first patella articulation path defining a first trochlear groove direction angle. The second trochlear groove component comprises a second patella articulation path defining a second trochlear groove direction angle. An assembly of the bi-condylar component and one of the first and second trochlear groove components forms a substantially complete femoral knee prosthesis. The second trochlear groove direction angle is different from the first trochlear groove direction angle.

Abstract: The present disclosure relates to a dynamic bioactive bone graft material having an engineered porosity. In one embodiment, a bone graft material is provided having bioactive glass fibers arranged in a porous matrix that is moldable into a desired shape for implantation. The material can be substantially without additives and can include at least one nanofiber. The porous matrix may include a combination of one or more pore sizes including nanopores, macropores, mesopores, and micropores. In another embodiment, a bone graft implant is provided having a matrix comprising a plurality of overlapping and interlocking bioactive glass fibers, and having a distributed porosity based on a range of pores provided in the bioactive glass fibers. The distributed porosity can comprise a combination of macropores, mesopores, and micropores, and the matrix can be formable into a desired shape for implantation into a patient.

Abstract: A femoral component (2) for mounting onto a femur and being adapted to articulate with a tibial bearing component in a knee prosthesis comprises proximal end portions (7, 10) adapted to be oriented towards the femur when the femoral component (2) is mounted thereon, and distal end portions adapted to be oriented towards the tibial bearing component when the knee prosthesis is fully extended. The proximal end portions (7) comprise posterior proximal end portions which are located on an posterior side of the femoral component and an anterior proximal end portion (10) which is located on an anterior side of the femoral component (2). The femoral component (2) further comprises a medial condyle (13) and a lateral condyle (14) which each extend from one of the posterior proximal end portions beyond the distal portions and towards the anterior proximal end portion (10) of the femoral component (2).

Abstract: Robotic mobility assistant exoskeleton with frame members, which are attached adjacent to biological joints, supplements relative movement between skeletal members. Mechanical joint defines a center of relative rotation of frame members about three mutually perpendicular axes with the center of relative rotation of frame members being displaced from the outer surfaces of skeletal members to correspond in position with the center of biological joint. Actuation devices including powered cable springs rotate frame members. Control system executes calibrated user specific posture sequences and activates power. Mechanical joint exhibits cylindrical guide surfaces defining a slidable or rotatable connection of frame members and has a radius intersecting the center of the biological joint. Node control network distributes computing load and reduces communications overhead. Map unit has object recognition system for monitoring environment.

Abstract: An ankle prosthesis comprising a tibial implant, a talar implant and an insert to articulate the implants. The top face of the tibial implant having an anchoring fin, and the bottom face is articulated with the top surface of the insert. The bottom face of the talar implant includes an anchor to the talar bone, and the top face is articulated with the bottom surface of the insert. The articulation surface being saddle-shaped and including a longitudinal central groove allowing the insert to move longitudinally and rotate transversely. The top face of the tibial implant includes, on its anterior edge, a shield covering the bottom anterior portion of the tibia, and the tibial face is inclined and forms an angle with the horizontal of between 15° and 45°. Passages are provided in the shield for bone screws passing through in an ascending manner and open on the inclined tibial face.

Abstract: Robotic mobility assistant exoskeleton with frame members, which are attached adjacent to biological joints, supplements relative movement between skeletal members. Mechanical joint defines a center of relative rotation of frame members about three mutually perpendicular axes with the center of relative rotation of frame members being displaced from the outer surfaces of skeletal members to correspond in position with the center of biological joint. Actuation devices including powered cable springs rotate frame members. Control system executes calibrated user specific posture sequences and activates power. Mechanical joint exhibits cylindrical guide surfaces defining a slidable or rotatable connection of frame members and has a radius intersecting the center of the biological joint. Node control network distributes computing load and reduces communications overhead. Map unit has object recognition system for monitoring environment.

Abstract: Embodiments of the invention include a knee arthroplasty trialing system and method with a femoral component and a tibial trial that has one or more spacers and one or more articular trials. Some embodiments include spacers and articular trials that may be moved in and out of the joint space without significantly distracting the femoral component away from the tibial trial. Some spacers and trials are configured to be inserted and removed from a joint space substantially along an anterior-posterior axis.