Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

Abstract: Medical devices are provided comprising a spike including proximal and distal ends, and a central axis extending from the proximal to the distal end; a valve body; a biasing body which biases the valve body; a distal tube that moves integrally with the valve body to both sides in the axial direction relative to the spike; a proximal tube fixed in the axial direction relative to the spike, the distal tube comprising a guided portion guided toward the proximal tube, and an engagement control unit which moves the guided portion toward one side in the radial direction by connection of the different medical device to the distal tube allowing the guided portion to engage with the proximal tube, and moves the guided portion toward the other side in the radial direction releasing engagement with the proximal tube when the different medical device is detached from the distal tube.

Abstract: The present invention relates to a negative pressure wound therapy device, system and method. The negative pressure wound therapy device is connected with a dressing, and comprises a housing, a control circuit board, a pump, and an aspiration conduit. The pump generates negative pressure. The pump may comprise a voltage-actuated deformation element (such as piezoelectric vibration element) to push fluid from an aspiration end to a discharge end. The aspiration conduit has a pump end and a dressing end. The pump end is fluidly connected to the aspiration end of the pump, and the dressing end is fluidly connected to the dressing used for covering a wound. The control circuit board is disposed in the housing, controls the pump to generate the negative pressure in the aspiration conduit, and applies negative pressure to the wound covered by the dressing via the aspiration conduit.

Abstract: A device comprising a trocar having a first end and comprising a cannulation and at least one fenestration proximal the first end; and a housing comprising a first port configured for the attachment of a first syringe and a second port configured for the attachment of a collection vessel, a first valve configured to selectively permit fluid flow through the cannulation of the trocar to the first port, and a second valve configured to selectively permit fluid flow through the cannulation of the trocar to the second port. The device allows the first syringe to draw up bone marrow in small volumes with high vacuum and then transfer the small draws into the collection vessel. The device may increase the recovery of desired cells residing in the bone marrow to be recovered during a bone marrow aspiration procedure.

Abstract: A wound dressing including a nonwoven absorbent layer including a layer of fabric comprising gel-forming fibers. The absorbent layer is gathered in a longitudinal direction by stitching through the layer of fabric using one or more resilient threads or yarns and an inelastic thread or yarn. The resilient and inelastic threads or yarns gather the layer of fabric so that the layer of fabric in use is configured to maintain close conformability with a wound during movement, and to elongate by 35% to 85% and then recover.

Abstract: A device holder (20) that holds a transfer device (800) is provided on a stage (10). The device (800) includes a first connector (810) to which a first container (910) is connectable, a second connector (820) to which a second container (950) is connectable, and a connection port (850) to which a syringe (980) is connectable. The stage (10) can be turned to a first turning position where the first connector (810) is located higher than the second connector (820) and a second turning position where the second connector (820) is located higher than the first connector (810). A second container holder (50) that holds the second container (950) coaxially with the second connector (820) turns together with the stage (10) and can be linearly moved along a direction of an axis of the second connector (820).

Abstract: Disclosed is an array 1 of wearable articles 20, each article comprising a main body 38 and a ring-like elastic belt 40 comprising a front belt and a back belt wherein at least the front belt or the back belt is an elastic member having an elastic member width in the transverse direction and a non-elastic region; wherein a first elastic member of a first article comprises a first non-elastic region; a second elastic member of a second article comprises a second non-elastic region; a third elastic member of a third article comprises a third non-elastic region; wherein the elastic member width of the first, second, and third elastic members are the same; and the first, second, and third non-elastic regions are different from each other.

Abstract: A system for connection to a catheter to aspirate clot from the vasculature of a patient includes a vacuum console and a canister assembly which can be removably mounted in a mounting region of the vacuum console. The canister assembly includes a clear canister with an interior and an open top. A lid is removably attachable over the open top of the clear canister, and the clear canister has a vacuum port and a pressure sensing port each formed in a wall of the canister. The vacuum port aligns with a vacuum connector on the enclosure and the pressure sensing port aligns with a pressure sensing connector on the enclosure when the canister assembly is mounted on the mounting region of the vacuum console. The clear canister has a filter plate configured to be suspended in the interior of the clear canister at a location mid-way between the open top and a bottom to separate clot from blood as they are aspirated from the catheter.

Abstract: A urinary catheter wetting apparatus (121) has a chamber defined by a forward section (123) opposite to a rearward section (125) each having an aperture (143,153) of which are axially aligned. A catheter tube is connected to a connector (161), the latter of which spans the chamber and initially seals the two apertures. The connector is slideable through the first facial surface (129) of forward section and the second end wall (131) of the rearward section so the catheter tube can be drawn through the chamber. A wetting applicator (151) holding a wetting agent is disposed in the chamber. Upon use, the connector passes through the chamber, applying pressure to the wetting applicator, thereby releasing the wetting agent from the wetting applicator and onto the catheter tube as it follows the connector through the chamber.

Abstract: A smart vial adapter is capable of measuring the dose of a drug that is withdrawn from a vial, measuring the time of a dose capture event, monitoring the vial temperature, measuring the amount of motion or perturbation the vial is subjected to, capturing various other parameters that can provide additional insights associated with the drug or the amount of the dose being drawn from the vial, and communicating the recorded information to a companion application on a computer, smartphone or other device. Related methods are also disclosed and claimed.

Abstract: A coupling member to be carried by a vessel of the container forming a vessel, and a cap intended to be screwed on the coupling member. The device also includes security features including a circumferential locking stop carried by the cap, and a complementary retractable circumferential locking stop carried by the coupling member. To this end, the coupling member includes a radial arm carrying a radial front arm, wherein the radial front arm and the radial arm extend in opposite directions. The front arm bears a lug forming the complementary retractable circumferential locking stop.

Abstract: A disposable, wearable article can be used for collecting a sample and performing urinalysis. The article incorporates a test port feature to simplify this function. The test port has a resealable cover that can be used to selectively expose an aperture through the backsheet of the disposable article. The test port is used to position test devices, such as urine test strips to urine collected in the disposable article.

Abstract: A urine collection device includes a collection member extending from a proximal end to a distal end. The proximal end includes an opening that provides access to an internal cavity of the collection member. The internal cavity includes a first chamber in fluid communication with a second chamber. The urine collection device includes a spacer in the second chamber, a first attachment member extending from a bottom wall of the collection member at the proximal end, a second attachment member extending from a top wall of the collection member at the proximal end, and an outlet for egressing urine from the internal cavity of the collection member. The first attachment member defines an aperture. The collection member is suitable to (i) direct urine from the first chamber to the second chamber and (ii) direct the urine in the second chamber distally toward the outlet.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In certain embodiments, a negative pressure wound therapy apparatus can include a spacer layer with an upper portion and a lower portion. The spacer layer can be configured to be wrapped around at least one edge of the absorbent layer with the upper portion of the spacer layer being above the absorbent layer and the lower portion of the spacer layer being below the absorbent layer. In some embodiments, a negative pressure wound therapy apparatus can include a first and second spacer layer and an absorbent layer. The first spacer layer can be positioned below the absorbent layer and the first spacer layer can have a perimeter larger than a perimeter of the absorbent layer. The second spacer layer can be positioned above the absorbent layer. The second spacer layer can have a perimeter larger than the perimeter of the absorbent layer.

Abstract: A sanitary article is equipped with a moisture-detecting RFID tag that includes a moisture-absorptive material; a moisture-detecting RFID tag adjacent to the moisture-absorptive material; and a relay antenna that is connected to the moisture-detecting RFID tag and that extends the communication range by relaying an output of the moisture-detecting RFID tag. Moreover, the moisture-detecting RFID tag includes an RFIC element, and an antenna element that is connected to the RFIC element. The moisture-detecting RFID tag outputs a variation of a communication distance or a signal intensity, originated from a variation of a moisture amount included in the moisture-absorptive material.

Abstract: Disclosed is a bladder drainage apparatus comprising a tube including a hollow interior extending through the tube, a flexible anchor, which behaves spring-like, connected to or at one end of the tube, and a magnetic member connected to or at the other end of the tube. The tube is moveable when the magnetic member is engaged by an external magnetic force, creating magnetic traction, and moving the tube, e.g., outward (from its original position, where the sphincter is typically closed), such that it holds open a sphincter, allowing urine to drain from the bladder, to the urethra, to outside of the body. When the external magnetic force is released, the magnetic engagement is terminated, and the force of the flexible anchor pulls the tube back to its original position, whereby the sphincter is again closed, and accordingly urine flow is stopped or otherwise limited.

Abstract: A system for providing therapy to a tissue site is described. The system can include a light sensor, a motion sensor, and a controller. The controller can be communicatively coupled to the source of negative pressure, the light sensor, and the motion sensor. In some embodiments, the controller can be configured to receive a first signal from the light sensor indicative of ambient light, receive a second signal from the motion sensor indicative of activity, and activate alert based on the first signal and the second signal.

Abstract: A device comprising a housing having a handle end and a treatment end. The treatment end is configured to provide an antimicrobial treatment and a heat treatment. The treatment end comprises an applicator having an applicator surface for providing at least the heat treatment. The device includes a heat generation unit configured to heat the applicator surface in use, a source of antimicrobial agent, and a control unit operatively connected to at least the heat generation unit for controlling the heat generation unit. The device can be a hand-held device and used to apply topical treatment to a treatment area of a subject.

Abstract: A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures, and methods of use. The split-tip catheter can include a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region can include an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion can taper from a first outer perimeter to a second smaller outer perimeter.

Abstract: Embodiments described herein are directed to tubing management members and urine collection systems including such tubing management members. In an embodiment, a tubing management member may be coupled and, in some embodiments, removably coupled to a drainage tube of the urine collection system. The tubing management member may include a plurality of attachment elements for attaching the tubing management member to the drainage tube.