Abstract: A method for judging a possibility of the onset of bovine leukemia caused by bovine leukemia virus BLV, wherein a bovine individual, in which an amino acid sequence defined by the amino acid numbers 75 to 78 of the .beta.1 domain of the bovine MHC Class II DR.beta. chain is Val-Asp-Thr-Tyr, is judged to have a possibility of the onset of the leukemia: and a method for judging a resistance to the onset of bovine leukemia caused by the bovine leukemia virus BLV, wherein a bovine individual, in which an amino acid defined by the amino acid number 78 of the .beta.1 domain of the bovine MHC Class II DR.beta. chain is Val, is judged to have a resistance to the onset of the leukemia.
Type:
Grant
Filed:
April 23, 1999
Date of Patent:
July 18, 2000
Assignee:
The Institute of Physical and Chemical Research
Abstract: This invention relates to an improved process for detecting and quantifying a desired nucleic acid sequence. The process involves synthesizing single stranded RNA, single stranded DNA, double-stranded DNA followed by detection using an electrochemiluminescent labeled binding species.
Abstract: The sequence of human papillomavirus present in a sample is determined by amplifying a portion of the L1 open reading frame of human papillomavirus genome to form L1 amplicons containing plus and minus amplified strands using MY09 and MY11 amplification primers, and then determining the positions of at least the A bases in the antisense amplicon using a consensus sequencing primer which is shifted six bases with respect to the MY09 primer (MY09-6). This primer has the sequence ARRGGAWACT GATCWARDTC (Seq. ID No.
Type:
Grant
Filed:
May 30, 1998
Date of Patent:
April 4, 2000
Assignee:
Visible Genetics Inc.
Inventors:
James B Mahony, Alan W Seadler, Timothy D Kierstead, Sylvia Chong