Patents Examined by Benjamin J Packard
  • Estrogen receptor modulators for treating mutants
    Patent number: 11278532
    Abstract: Uses and methods that include an effective amount of Compound (A), or a pharmaceutically acceptable salt thereof, are described herein for treating breast cancer in a subject in need thereof, wherein the breast cancer has at least one point mutation within the Estrogen Receptor 1 (ESR1) that encodes Estrogen receptor alpha (ER?).
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: March 22, 2022
    Assignee: Recurium IP Holdings, LLC
    Inventors: Ahmed Abdi Samatar, Jiali Li, Jianhui Ma, Sayee Gajanan Hegde, Peter Qinhua Huang, Kevin Duane Bunker, Fernando Donate
  • Yeast-based masks for improved skin, hair and scalp health
    Patent number: 11278490
    Abstract: The subject invention provides materials and methods for improving facial skin, hair and scalp health using cosmetic yeast-based masks. In a specific embodiment, the subject invention provides a yeast-based mask for application to the face, which can improve the health and appearance of thereof. In another specific embodiment, the subject invention provides a yeast-based mask for application to the hair and scalp, which can aid in preventing hair loss, as well as improve the health and appearance of the hair and scalp. Methods of using the yeast-based masks are also provided.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: March 22, 2022
    Assignee: LOCUS IP COMPANY, LLC
    Inventors: Sean Farmer, Ken Alibek
  • Personal care composition
    Patent number: 11278475
    Abstract: Disclosed are personal care compositions comprising a fibrous material of natural origin and obtained from plants. The fibrous material comprises micro-scaled and/or nano-scaled fibril agglomerates. Such compositions show pleasant skin feel and comfort during and after application, as well as fast drying and fast absorption into skin. The compositions obtained are also particularly well suited for the topical delivery of cosmetic and pharmaceutical active substances into skin. Additionally, a method to obtain said personal care composition is disclosed.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: March 22, 2022
    Assignee: Weidmann Holding AG
    Inventors: Stefan Truniger, Tobias Wolfinger
  • Treatment for tumors driven by metabolic dysfunction
    Patent number: 11273142
    Abstract: The present disclosure relates to modified or polymer conjugated MetAP2 inhibitors. The present disclosure also relates to methods of treating metabolically-driven diseases and disorders, such as certain cancers.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: March 15, 2022
    Assignee: SynDevRx, Inc.
    Inventors: James Shanahan, Peter Cornelius
  • SNAP25 antisense oligonucleotides
    Patent number: 11261448
    Abstract: Provided are peptide nucleic acid derivatives targeting a 3? splice site of the human SNAP25 pre-mRNA. The peptide nucleic acid derivatives potently induce at least a splice variant of the human SNAP25 mRNA in cells, and are useful to safely treat dermatological indications or conditions involving the expression of the human SNAP25 protein by topical administration.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: March 1, 2022
    Assignee: OliPass Corporation
    Inventors: Daram Jung, Kangwon Jang, Bongjun Cho, Min Wook Shin, Hyun Ju Jeon, Soyoung Kim
  • Nucleic acid-peptide capsule complexes
    Patent number: 11252957
    Abstract: Described herein are nucleic acid-peptide capsule complexes or nanoparticles comprising pre-formed peptide capsules and nucleic acids bound the exterior surface of the capsule, such that the wrap around the capsule membrane. The peptide capsules comprise bilayer membrane defining a liquid-receiving interior space and comprises a plurality of branched, amphipathic peptides. Method of making and using such complexes for delivering nucleic acids in vivo and in vitro are also described.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: February 22, 2022
    Assignee: Kansas State University Research Foundation
    Inventors: John M. Tomich, Gerald Reeck, Luz Adriana Avila Flores, Raman Chandrasekar
  • Method and apparatus for providing polyiodide resin powder-enhanced personal protective equipment (PPE)
    Patent number: 11253623
    Abstract: Disclosed is a method and apparatus for providing polyiodide resin-enhanced personal protective equipment (PPE) including but not limited to face masks, gloves, gowns and respirators. The disclosed method comprises the application of a polyiodinated ink polymer in or on one or more targeted surfaces of PPE to create a molecular sub-microscopic protective barrier between the equipment and the user. The disclosed system provides a PPE device capable of direct contact kill of organisms. In addition, the system provides for a sustained kill of organisms for up to 96 hours. The resultant PPE device is broadly effective against viral, bacterial, fungicidal and other microbial agents.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: February 22, 2022
    Inventors: Albert Rego, Lynn R. Detlor, Aileen Law
  • Topical composition for rejuvenating and/or repairing skin, methods, uses and kits thereof
    Patent number: 11253466
    Abstract: The present description relates to a skin ointment or topical composition for skin rejuvenation and/or repair. The composition generally comprises: a biocompatible mixture of probiotics (e.g., probiotic yeast and/or bacteria); admixed with one or more of: exfoliating agents, mud and/or clay, blood circulation promoting agent, and nutrients. Methods, uses and kits relating to same are also described.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: February 22, 2022
    Assignee: DAVINCIA INC.
    Inventor: Nathalie Forget
  • Methods and compositions of preventing and treating dental caries
    Patent number: 11246895
    Abstract: Provided herein are methods and compositions related to bacteria of genus Rothia useful as therapeutic agents for dental caries.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: February 15, 2022
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Pooja Balani, Felicitas Bidlack, Xuesong He, Megan Pugach-Gordon, Wenyuan Shi, Jacqueline Starr, Daniel Ferrer
  • Sprayable cosmetic agent II
    Patent number: 11246810
    Abstract: Cosmetic composition for cosmetic treatment of keratinous fibers, comprising: (a) from about 0.1 to about 5.0 wt % fibers (b) from about 5.0 to about 19 wt % ethanol (c) from about 78 to about 94 wt % propellant.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: February 15, 2022
    Assignee: HENKEL AG & CO. KGAA
    Inventors: Diane Metten, Rene Scheffler, Julia Bibiane Lange, Cyrielle Martinez, Thorsten Knappe, Rolf Bayersdoerfer
  • Biomedical composition for skin care and/or maintenance and delaying and/or inhibiting skin aging and the use thereof
    Patent number: 11246822
    Abstract: A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: February 15, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Ting-Yu Shih, Lu-Chih Wang, Yuan-Kun Yu, Yi-Ting Hsieh, Yu-Chun Liu, Jing-Wen Tang
  • Coupling agent produced from naturally fermented and sustainable additives
    Patent number: 11241508
    Abstract: A coupling agent composition is provided and includes a plurality of non-toxic components, a neutralizing agent, and a chelating agent. The plurality of non-toxic components is derived from one or more natural resource materials and is an amount equal to or greater than 97 weight percent (wt %) of the composition. The plurality of non-toxic components includes a carrier, at least one water soluble polyol selected from the group consisting of propanediol, pentylene glycol, and butylene glycol in an amount of from 9.00 to 11.00 wt %, and a thickening agent of 0.10 to 3.00 wt % having a naturally derived soluble polymer additive selected from a group consisting of xanthan gum, carrageenan, guar, locust bean, sodium hyaluronate, sodium alginate, acacia, tara gum, tamarind seed, succinoglycan, scleroglucan, and mannan in an amount of 0.50-3.00 wt %.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: February 8, 2022
    Assignee: Wiesman Holdings, LLC
    Inventors: Jon Wiesman, George Deckner
  • Oral care compositions
    Patent number: 11234912
    Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: February 1, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Aarti Rege, Michael Prencipe
  • Treatment of peripheral neuropathy induced by cancer chemotherapy
    Patent number: 11234947
    Abstract: Methods of treating peripheral neuropathy induced by cancer chemotherapy and/or of stimulating the regeneration of peripheral sensory nerve fibers, comprising administering topically to one or more areas of the skin capsaicin or a capsaicinoid or topical TRPV1 agonist, to a patient in need thereof, wherein the capsaicin or capsaicinoid or TRPV1 agonist is administered after the patient has received cancer chemotherapy, and wherein the patient is not currently receiving cancer chemotherapy. Related kits comprising capsaicin-containing cutaneous patches for use with said methods.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: February 1, 2022
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventor: Praveen Anand
  • Herbicidal composition comprising at least one phenolic active compound
    Patent number: 11229204
    Abstract: The present invention relates to a herbicidal composition comprising at least one phenolic active compound being myricitrin. The invention also relates to the use of such a herbicidal composition.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: January 25, 2022
    Assignee: Université de Liège
    Inventors: Sofiene Ben Kaab, Haissam Jijakli, Riadh Ksouri, Olivier Parisi, Simon Dal Maso
  • Bleeding control device and method of manufacture and use
    Patent number: 11229581
    Abstract: A bleeding control device is provided. The device includes an elongate member with a holding portion and an application portion. A known amount of hemostatic solute within a solution is administered to the application portion and allowed to dry. The elongate member is then sterilized. The resulting bleeding control device may be used during medical procedures such as root canal procedures and others.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: January 25, 2022
    Inventor: Ryan L. Reese
  • Synergistic compositions of dehydroacetic acid and methods for reducing yellowing in various end-user compositions
    Patent number: 11224222
    Abstract: What is described herein is a stable and reduced-yellowing/non-yellowing synergistic preservative composition comprising: (i) about 0.1 wt. % to about 40 wt. % of dehydroacetic acid (DHA); and about 0.1 wt. % to about 99.9 wt. % of at least one aprotic solvent. Also described herein are aqueous and non-aqueous based preservative compositions for various end-user applications, and processes for preparing and using such compositions to reduce yellowing of DHA when added to the end-user applications.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: January 18, 2022
    Assignee: ISP Investments LLC
    Inventors: Raman Premachandran, Kalpa Metha, Jyoti Gupta, Najeeb H. Hakimi, Karen W Winkowski
  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 11220512
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: January 11, 2022
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Method of strengthening oxidatively-treated hair
    Patent number: 11219589
    Abstract: The invention provides a method of strengthening the fibres of oxidatively-treated hair, the method comprising the sequential steps of: (i) washing the oxidatively-treated hair; (ii) soaking the washed hair in an aqueous treatment composition, and (iii) drying the soaked hair; characterised in that the aqueous treatment composition comprises at least 1% N-acetyl glycine (by weight based on the total weight of the composition).15 The invention also provides the use of an aqueous treatment composition comprising at least 1% N-acetyl glycine (by weight based on the total weight of the composition), for the enhanced strengthening of oxidatively-treated hair fibres relative to virgin hair fibres.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: January 11, 2022
    Assignee: CONOPCO, INC
    Inventor: Prem Kumar Cheyalazhagan Paul
  • Nitric oxide-releasing antibiotics, methods of making, and methods of use
    Patent number: 11220516
    Abstract: The present disclosure provides for modified antibiotic compounds, methods of making modified antibiotic compounds, methods of use, products including modified antibiotic compounds, and the like. The modified antibiotic compound comprises a nitric oxide release agent covalently attached to an antibiotic molecule, such as S-nitroso-N-acetylpenicillamine covalently attached to ampicillin.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: January 11, 2022
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Hitesh Handa, Sean P. Hopkins, Priyadarshini Singha, Christina Danielle Workman