Abstract: The invention relates to a pharmaceutical bottle having a neck region with an open end, pills therein, a fibrous hygroscope member, such as a cotton wad, in the neck region of said bottle and a closure cap sealing the bottle opening. The neck region has on its inner surface a leaflet retaining ring which serves to hold the leaflet in place within the bottle immediately after the insertion. The tendency of the leaflet to unfold or open, causes the edges of the leaflet to engage the retaining ring and to be held in place at least until the bottle is sealed. The leaflet is in compression engagement with the fibrous hygroscope member, such that the pills are substantially prevented from moving relative to one another.