Patents Examined by Blaine Doletski
  • Method for producing ?-aminocarbonyl compound
    Patent number: 8507715
    Abstract: An optically active ?-aminocarbonyl compound is obtained by a Mannich reaction between an aldimine in which: nitrogen is protected and a malonic acid diester, in the presence of optically active BINOL and dialkyl magnesium (in which two alkyl groups are the same or different) in an amount 1 to 2 molar times the amount of the BINOL.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: August 13, 2013
    Assignee: National University Corporation Nagoya University
    Inventors: Kazuaki Ishihara, Manabu Hatano, Takahiro Horibe