Abstract: Multiple interactions, such as Compton scattering, inside a PET detector are used to predict an incident photon's direction for identifying true coincidence events versus scatter/random coincidence events by creating a cone shaped shell projection defining a range of possible flight directions for the incident photon. The disclosed techniques can be used as prior information to improve the image reconstruction process. The disclosed techniques can be implemented in a LYSO/SiPM-based layer stacked detector, which can precisely register multiple interactions' 3D position.

Abstract: A Compton camera for medical imaging is divided into segments with each segment including part of the scatter detector, part of the catcher detector, and part of the electronics. The different segments may be positioned together to form the Compton camera arcing around part of the patient space. By using segments, any number of segments may be used to fit with a multi-modality imaging system.

Abstract: An image acquisition system includes a radiation source configured to output radiation toward an object, a rotating stage configured to rotate the object around a rotation axis, a radiation camera having an input surface to which the radiation transmitted through the object is input and an image sensor capable of TDI control, and an image processing apparatus configured to generate a radiographic image of the object at an imaging plane P based on the image data. The angle formed between the rotation axis of the rotating stage and the input surface of the radiation camera is set in accordance with the FOD which is the distance between the radiation source and an imaging plane in the object. The radiation camera is configured to perform TDI control in the image sensor in synchronization with the rotational speed of the object rotated by the rotating stage.

Abstract: Disclosed is a method for analysing FluoroSpot assays. The method comprises illuminating a well of an assay plate with at least one excitation light, capturing at least one image of the well, in raw image format, for each excitation light, generating a model of analyte release distribution in the well for each excitation light, and clustering a plurality of co-positioned fluorospots as a multiple secretion fluorospot, wherein the clustering is performed for all generated models, and wherein the clustering determines at least one multiple secretion fluorospot. The generation of the model of analyte release distribution for a given excitation light comprises deconvolving the captured at least one image of the well to estimate a pre-diffusion analyte distribution, and detecting potential analyte release sites based on local maxima therein.

Abstract: A bracket body releasably secures a compression element to the compression arm of a breast imaging system. A pair of parallel lateral arms extends from a rigid frame which extends from the bracket. A span connects the ends of the lateral arms opposite the bracket and a flexible membrane extends from the span towards the bracket body.

Abstract: A radiation sensing device is provided in the present disclosure. The radiation sensing device includes a substrate and a plurality of semiconductor units. The semiconductor units are disposed on the substrate, and at least one of the semiconductor units includes a first gate electrode, an active layer, and a second gate electrode. The active layer is disposed on the first gate electrode, and the second gate electrode is disposed on the active layer. The second gate electrode has a positive bias voltage during a standby mode. The second electrode may be configured to have a positive bias voltage during the standby mode for improving influence on electrical properties of the semiconductor unit after the semiconductor unit is irradiated by radiation.

Abstract: Presented herein are systems and methods directed to a multispectral absorption-based imaging approach offering improved detection, localization, and quantification of gas emission. The imaging technology described herein utilizes an optical sensor and broadband illumination in combination with specialized reflector installments mounted about the site. The optical sensor detects light (e.g., reflected) from locations along the reflector installment. Lines-of-sight from the optical sensor to locations along the reflector installment sweep out an “optical curtain” partially enclosing and/or forming a boundary near various assets to be monitored. Optical absorption signatures from leaking gas crossing the optical curtain can be used to detect, localize, and obtain quantitative measures characterizing the leak.

Abstract: A photon-counting X-ray detector includes a converter element constructed to convert incident X-rays into electrical signals in dependence on a deposition of energy in the converter element, and an evaluation device. The evaluation device includes a pulse-generator to generate and output an electrical pulse based upon an electrical signal fed from the converter element; a differentiator to generate a differentiated signal of the electrical pulse output by the pulse-generator; and a first comparator to compare the generated differentiated signal with a first threshold value and, based upon the comparison, to output a binary output signal for a period for which the threshold value is exceeded.

Abstract: An imaging control apparatus includes a hardware processor that acquires a first imaging condition set as a imaging condition for a preliminary exposure performed prior to a main exposure that performs an exposure of radiation on a subject, and the hardware processor performs control based on compatibility of the acquired first imaging condition and a second imaging condition input as an imaging condition for the subject.

Abstract: Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.

Abstract: A system is provided. The system includes a light source configured to emit an infrared light to illuminate an eye of a user. The system includes a grating disposed facing the eye and including a birefringent material film configured with a uniform birefringence lower than or equal to 0.1. The grating is configured to diffract the infrared light reflected from the eye, and transmit a visible light from a real world environment toward the eye, with a diffraction efficiency less than a predetermined threshold. The system includes an optical sensor configured to receive the diffracted infrared light and generate an image of the eye based on the diffracted infrared light.

Abstract: A method for the real-time control of exposure to an X-ray dose emitted by a generator tube for generating an X-ray beam and received by a detector includes a flat panel detector, comprising a set of pixels organized into a matrix along rows and columns and configured so as to generate signals on the basis of the X-ray dose impinging on the detector, the generator tube comprising a control unit for controlling the generator tube that is configured so as to control an emitted X-ray dose, the control method comprising the following steps: exposing the flat panel detector to an X-ray dose emitted by the generator tube for generating an X-ray beam; repeatedly reading out at least one of the rows of pixels while the flat panel detector is exposed to the X-ray dose; determining a payload signal and a stray signal based on the signals from the readout of the at least one of the rows; transmitting the payload signal to the control unit for controlling the generator tube.

Abstract: A fluoride sensor includes an aluminum layer situated on a distal end face of an optical fiber. A light source directs light into the optical fiber at a proximal end and reflected light from the aluminum layer at the distal end face is directed by the fiber to a detector. A rate of change of a detector signal is processed to produce an estimate of a concentration of fluoride.

Abstract: Provided herein are neutron imaging systems (e.g., radiography and tomography) systems and methods that provide, for example, high-quality, high throughput 2D and 3D fast or thermal neutron and/or X-ray images. Such systems and methods find use for the commercial-scale imaging of industrial components. In certain embodiments, provided herein are system comprising a plurality of independent neutron absorber-lined collimators (e.g., 4 or more collimators) extending outwards from a central neutron source assembly.

Abstract: For gamma ray detection, 3D tiling is made possible by modules that include a gamma ray detector with at least some electronics extending away from the detector as a side wall, leaving an air or low attenuation gap behind the gamma ray detector. The modules may be stacked to form arrays of any shape in 3D, including stacking to form a Compton detector with a scatter detector separated from the catcher detector by the low attenuation gap where the electronics form at least one side wall between the detectors. The modules may be stacked so that the detectors from the different modules are in different planes and/or not part of a same surface (e.g., same surface provided with just 1D or 2D tiling).

Abstract: A specimen inspection machine includes a case, a carrying device, an inspection device, a sensing device and a control device. The carrying device is disposed in the case. The inspection device is disposed on the carrying device. The inspection device has accommodating grooves. Each accommodating groove is used for accommodating an inspection sample. The inspection sample at least includes a specimen. The sensing device is disposed in the case on a side of the case opposite the carrying device. The sensing device senses the inspection device to generate first and second sensing signals. The control device is disposed in the case. The control device determines whether the inspection device is disposed in the correct position according to the first sensing signals, and determines whether inspection samples are placed in the accommodating grooves according to the second sensing signals to inspect the accommodating grooves placed with the inspection samples.

Abstract: The present disclosure is related to a system. The system may include a gantry, a detector assembly including a plurality of detector modules arranged on the gantry, and/or a cooling assembly configured to cool the detector assemble. Each of the plurality of detector modules may include a crystal array configured to detect radiation rays, and a shielding component configured to shield the crystal array from an electromagnetic interference. The cooling assembly may include a plurality of cooling components. Each of the plurality of cooling components may be embedded in a corresponding detector module of the plurality of detector modules.

Abstract: A method of calibrating a monitoring system (10,14) is described in which a calibration phantom (70) is located with its center located approximately at the isocenter of a treatment room through which a treatment apparatus (16) is arranged to direct radiation, wherein the surface of the calibration phantom (70) closest to an image capture device (72) of the monitoring system (10,14) is inclined approximately 45° relative to the camera plane of an image capture device of the monitoring system. Images of the calibration phantom (70) are then captured using the image capture device (72) and the images are processed to generate a model of the imaged surface of the calibration phantom.

Abstract: Dual layer detector (XD) for X-ray imaging, comprising at least two light sensitive surfaces (LSS1,LSS2). The dual layer detector further comprises a first scintillator layer (SL, SL1) including at least one scintillator element (SE) capable of converting X-radiation into light, the element having two faces, an ingress face (S1) for admitting X-radiation into the element (SE) and an egress face (S2) distal from the ingress face (S1), wherein the two faces (S1,S2) are arranged shifted relative to each other, so that a longitudinal axis (LAX) of the scintillator element (SE) is inclined relative to a normal (n) of the layer.

Abstract: Perovskite single crystal X-ray radiation detector devices including an X-ray wavelength-responsive active layer including an organolead trihalide perovskite single crystal, a substrate layer comprising an oxide, and a binding layer disposed between the active layer and the substrate layer. The binding layer including a binding molecule having a first functional group that bonds to the organolead trihalide perovskite single crystal and a second functional group that bonds with the oxide. Inclusion of the binding layer advantageously reduces device noise while retaining signal intensity.