Abstract: The present invention discloses an ophthalmic device with a retinal vascularization monitoring system and associated methods. In some embodiments, the ophthalmic device can be a contact lens with a retinal vascularization monitoring system that can be used to monitor temporal changes of a pulsating vessel forming part of the retinal vascularization. Further, the retinal vascularization monitoring system may include elements for delivering a signal, including an audible and/or visual message, to the user that can be useful for identifying abnormal conditions such as a cardiac failure without delay. The audible and/or visual messages can be signals communicated to the user using one or both of the ophthalmic device and a wireless device in communication with the ophthalmic device.

Abstract: Sparse tracking is used in acoustic radiation force impulse imaging. The tracking is performed sparsely. The displacements are measured only one or a few times for each receive line. While this may result in insufficient information to determine the displacement phase shift and/or maximum displacement over time, the resulting displacement samples for different receive lines as a function of time may be used together to estimate the velocity, such as with a Radon transform. The estimation may be less susceptible to noise from the scarcity of displacement samples by using compressive sensing.

Abstract: An ultrasonic probe includes, a transducer transmitting and receiving ultrasonic waves, and converting ultrasonic signals into voltage signals and vice versa, a first circuit configured to transmit pulse voltage signals to the transducer and receive the voltage signals from the transducer, a second circuit configured to convert the voltage signals received from the first circuit into digital values from analog values, a battery unit configured to supply electric power to the first circuit and the second circuit, and a substrate being provided with the transducer, the first circuit and the second circuit, the first circuit being disposed on a first surface of the substrate, and the second circuit being disposed on a second surface opposite to the first surface of the substrate.

Abstract: Example apparatus and methods perform magnetic resonance fingerprinting (MRF) for arterial spin labeling (ASL) based parameter quantification. ASL with MRF produces a nuclear magnetic resonance signal time course from which simultaneous quantification of ASL perfusion-related parameters can be achieved. The parameters may include cerebral blood flow, transit time, T1, or other parameters. The quantification uses values from a dictionary of signal time courses that were generated or augmented using Bloch simulation, knowledge of the sequence, or previous observations. The dictionary may account for inflow or outflow of labeled spins and may model arterial input. An ASL-MRF pulse sequence may differ from conventional pulse sequences. For example, an ASL-MRF pulse sequence may include non-uniform control pulses, non-uniform label pulses, non-uniform post labeling delay time, non-uniform background suppression pulses, non-uniform acquisition repetition time, or non-uniform acquisition flip angle.

Abstract: Embodiments of the invention relate generally to systems and methods for providing embolic protection to a medical procedure by filtration of debris generated by the medical procedure. The system and methods include an embolic protection device having an ultrasound transducer for assisting in intravascular navigation of the device.

Abstract: An ultrasonic data acquisition apparatus includes an inner layer, a guiding rail surrounding the inner layer and an ultrasonic probe positioned outside of the inner layer and connected to the guiding rail. The inner layer includes an inner surface and an outer surface. The inner layer is curved along a circumference direction. The ultrasonic probe includes a far end adjacent to the tissue and a near end opposite to the far end. When the ultrasonic data acquisition apparatus is in working, the ultrasonic probe is movable relative to the inner layer along the circumference direction while keeping the far end consistently abutting against the outer surface of the inner layer. Besides, a system for acquiring ultrasonic data and a control method of the ultrasonic data acquisition apparatus are also disclosed.

Abstract: A stylet (100) includes a handle assembly (102) with an indicator display (112) and a stiff wire assembly (120) extending distally from the handle assembly (102) having a non-imaging ultrasonic device on a distal end. The stylet includes a circuit assembly having one or more of a pulser (120), a transmit/receive chip (132), a bandpass filter (134), a differential amplifier (136), an ADC (138), and an MCU (140), operable to control the operation of the ultrasonic device and to receive and analyze data from the ultrasonic device to facilitate implantation of a device such as a catheter.

Abstract: A method is described for acquiring 3D quantitative ultrasound elastography volumes. A 2D ultrasound transducer scans a volume of tissue through which shear waves are created using an external vibration source, the synchronized measurement of tissue motion within the plane of the ultrasound transducer with the measurement of the transducer location in space, the reconstruction of tissue displacements and/or tissue velocities in time and space over a volume from this synchronized measurement, and the computation of one or several mechanical properties of tissue from this volumetric measurement of displacements. The tissue motion in the plane of the transducer may be measured at a high effective frame rate in the axial direction of the transducer, or in the axial and lateral directions of the transducer. The tissue displacements and/or tissue velocities over the measured volume may be interpolated over a regular grid in order to facilitate computation of mechanical properties.

Abstract: There is disclosed a respiration rate monitoring system and method using a non-invasive device and method of monitoring it nearly continuously. One aspect includes receiving a series of signal data points from an optical sensor, detecting a series of peaks or valleys for the filtered signal data points, determining the time difference between individual peaks or valleys of the series of peaks or valleys to produce a series of time difference values, detecting peaks or valleys for the series of time difference values, determining widths between the peaks or valleys of the series of time difference values, and estimating a respiration rate from the widths between the peaks or valleys of the series of time difference values, and converting the estimation of a respiration rate to an indicator indicative of a respiration rate.

Abstract: Contrast administration data that relates to operation of a contrast media injector system (602) may be converted from at least one format (e.g., a CAN-compliant format) to at least one other format (e.g., an HL-7-compliant format) for use by a medical system (600). Data on contrast media prescribed for an imaging operation using an imaging system (690), data on contrast media dispensed from a contrast media storage/dispensing unit (500) for use in this imaging operation, and data on contrast media actually administered/injected by a contrast media injector system (602) for this imaging operation may be stored in a data structure (780). Patient renal function data may be used to control the dispensing of contrast media from the contrast media/storage/dispensing unit (500), to control the operation of the contrast media injector system (602), or both, and may be stored in the data structure (780) as well.

Abstract: A hybrid imaging system includes a magnetic resonance scanner and a second modality imaging system disposed in the same radio frequency isolation space. The second modality imaging system includes radiation detectors configured to detect at least one of high energy particles and high energy photons. In some embodiments a retractable radio frequency screen is selectively extendible into a gap between the magnetic resonance scanner and the second modality imaging system. In some embodiments shim coils are disposed with the magnetic resonance scanner and are configured to compensate for distortion of the static magnetic field of the magnetic resonance scanner produced by proximity of the second modality imaging system.

Abstract: A subject information acquisition apparatus of the present invention includes a transmission/reception unit including a plurality conversion elements which transmit an elastic wave to the subject and receive a reflected wave that is reflected at each position in the subject, a scan line signal acquisition unit which acquires a plurality of signals corresponding to the reflected waves from each position in the subject as scan line signals by using a plurality of reception signals outputted from the conversion elements, and a processing unit which acquires moving information of the object by using the plurality of scan line signals. The processing unit acquires the moving information of the object on the basis of a distribution of cross-correlation values on a plane represented by two axes including an axis of time difference and an axis of distance difference by using a plurality of cross-correlation values between scan line signals at different positions.

Abstract: The invention provides an analysis method of ultrasound echo signals based on statistics of scatterer distributions. The beginning of steps, choosing an ultrasound echo signal as a center, and calculating the signal image values of all ultrasound echo signals within a window block in an ultrasound image data to obtain an ultrasound scatterer value. Then, choosing another ultrasound echo signal as the center to repeat the previous steps until all of ultrasound echo signals may be calculated. The interval between each of ultrasound echo signal is one point distance. Finally, to output an ultrasound scatterer mode image with all ultrasound scatterer values by utilizing color scale. The ultrasound scatterer mode image can assist doctor to confirm the relative region of lesion in a target organ.

Abstract: A surgical positioning system is provided that includes a dimensioned grid having a plurality of dimensioned radio-opaque lines corresponding to surgical variables and a substrate connected to or integral with the grid. This system is used to obtain subject specific data from an image of a subject obtained during a surgical procedure by following the steps of: providing a grid having a plurality of dimensioned radio-opaque lines relating to surgical variables; placing the subject on a substrate; and obtaining subject specific data from an image of said subject. This invention relates to an apparatus made of a grid having a plurality of dimensioned radio-opaque lines relating to surgical variables and a sealable container sized to receive the dimensioned grid.

Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.

Abstract: A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode.

Abstract: An apparatus for registering medical images includes a processor configured to acquire, via an ultrasound probe, a first cross-section of a first medical image, the first cross-section comprising a reference point of an object; and a memory configured to store a second medical image. The processor is configured to obtain a second cross-section of the second medical image corresponding to the first cross-section by using the reference point, and register the first and second medical images with each other.

Abstract: Acoustic reciprocity between transmit and receive is used for coherence ultrasound imaging. Rather than finding coherence across the receive channels, coherence is found across transmit channels. Broad transmit beams are used for different transmit elements or apertures to create beamformed frames of data. The coherence between these transmit channel frames of beamformed data is calculated and used for imaging.

Abstract: In an MRI magnet structure for use with a radiation beam source as an assembly, magnet coils of varying diameters are concentrically arranged along a magnetic axis, the magnetic coils not sharing a common inner or outer radius. Mechanical support is provided to retain the magnetic coils in necessary relative fixed positions. The patient bore tube is provided through the assembly and defines a patient bore axis in an essentially horizontal direction such that the magnetic axis is inclined to the patient bore axis by an angle of 30°-60°. At least one radiation therapy beam access cavity provides access in a straight line for a radiation therapy beam to reach a treatment region within the magnet structure.

Abstract: A diagnostic assembly (30, 320) and method for detecting a presence of cancer in a breast of a patient. The diagnostic assembly (20, 320) comprises a frame (22, 322), at least one cold bar (26, 326, 426) supported by the frame (22, 322) for receiving a hand of the patient, and a temperature controller (72) in communication with the cold bar (26, 326, 426) to maintain a constant temperature of the cold bar (26, 326, 426). The method comprises the steps of cooling at least one hand of the patient and recording a test thermal image of the breast of the patient after the hand of the patient has been cooled. The step of cooling the hand of the patient includes receiving the hand of the patient on the cold bar (26, 326, 426) to transfer heat from the hand of the patient to the cold bar (26, 326, 426), and maintaining the cold bar (26, 326, 426) at a preselected temperature.