Patents Examined by Brianna K Swartwout
  • Nanobody target GCC and uses in chimeric antigen receptor cell therapy
    Patent number: 11970548
    Abstract: The compositions and methods described herein are directed to treating solid tumors using CAR T therapy and/or antibodies targeting GCC. The compositions include CAR comprising an extracellular domain that binds GCC.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: April 30, 2024
    Assignees: Innovative Cellular Therapeutics Holdings, Ltd., Innovative Cellular Therapeutics, Inc.
    Inventors: Zhiyuan Cao, Yuzhe Peng, Lei Xiao, Zhao Wu, Le Tian
  • Anti-CD47 antibody and uses thereof
    Patent number: 11807685
    Abstract: Disclosed is an antibody that selectively binds CD47 on tumor cells. Also disclosed is a method for treating cancer in a subject, comprising administering to the subject an effective amount of the antibody disclosed.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: November 7, 2023
    Assignee: The UAB Research Foundation
    Inventor: Xiaoguang Margaret Liu