Abstract: A one-step process for preparing cross-linked poly-.beta.-alanine as microspheres having narrow size distribution comprises polymerizing acrylamide with a polyfunctional compound copolymerizable with acrylamide (with the polyfunctional compound also acting as the cross-linking agent) in an organic solvent or a mixtured such solvents in the presence of an ionic polymerization initiator and a suspension agent. The resulting microspheres may be impregnated with a pharmaceutically or cosmetically active substance.
Type:
Grant
Filed:
June 14, 1990
Date of Patent:
December 31, 1991
Assignee:
L'Oreal
Inventors:
Claudine Lapoiriere, Claude Mahieu, Christos Papantoniou
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