Abstract: A blood flow measuring unit of a blood flow measurement apparatus of an embodiment includes an optical system for applying an OCT scan to an eye fundus and obtains blood flow information based on data acquired by the OCT scan. A movement mechanism moves the optical system. A controller applies a first movement control to the movement mechanism to move the optical system in a first direction orthogonal to an optical axis of the optical system by a predetermined distance from the optical axis. A judging unit judges occurrence of vignetting based on a detection result of return light of light incident on the eye through the optical system after the first movement control. The controller applies a second movement control to the movement mechanism to further move the optical system based on a judgement result obtained by the judging unit.

Abstract: An electrical muscle stimulation (EMS) suit having electrodes affixed thereto is disclosed. The EMS suit may include a vest portion comprising a left front portion, a right front portion, and a back portion, as well as a processor and memory storing pulse parameter settings. In some embodiments, the left front portion has a first pair of electrodes on a first channel, and the right front portion has a second pair of electrodes on a second channel. In some embodiments, the back portion has a third pair of electrodes on a third channel and positioned in a left half of the back portion, as well as a fourth pair of electrodes on a fourth channel and positioned in a left half of the back portion. During operation of the EMS suit, electrical impulses are delivered via the pairs of electrodes in accordance with the pulse parameter settings to elicit muscle contraction.

Abstract: The present disclosure pertains to a system for providing client-side physiological condition estimations during a live video session. In some embodiments, the system includes a first client computer system that is caused to: (i) store a neural network on one or more computer-readable storage media of the first client computer system, (ii) obtain a live video stream of an individual via a camera of the first client computer system during a video streaming session between the first client computer system and a second client computer system, (iii) provide, during the video streaming session, video data of the live video stream as input to the neural network to obtain physiological condition information from the neural network, and (iv) provide, during the video streaming session, the physiological condition information for presentation at the second client computer system.

Abstract: Described herein are methods, software, systems and devices for detecting the presence of an abnormality in an organ, tissue, body, or portion thereof of a subject by analysis of the electromagnetic fields generated by the organ, tissue, body, or portion thereof.

Abstract: Described herein are apparatuses (e.g., systems and devices) and methods of delivering nanosecond pulsed electrical fields (nsPEF). In particular, these apparatuses and methods may provide enhanced safety and robust operation over even very short (e.g., nanosecond and sub-nanosecond pulses) and high voltage pulsing; these benefits may be accomplished by multi-functional isolation of various subsystems and components of the apparatus, even including the low-voltage, control and command portions of the apparatus with extremely low capacitance, high voltage isolation.

Abstract: Disclosed herein are various spinal cord stimulation devices with thin film components, including a device having a flexible section disposed along a length of the elongate lead body of the device. Other stimulation devices have a flexible section disposed within the electrode body of the device. Further devices include both a flexible section disposed within the elongate lead body and a flexible section disposed within the electrode body of the device.

Abstract: The invention provides a device for treating at least one of rhinitis, congestion, and/or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, coughing, sneezing, nasal or throat irritation and itching, and difficulty sleeping. The device includes an elongate body, a retractable and expandable multi-segment end effector, and handle, that, as a whole, provide a high level of precise control and feedback to an operator during a procedure. The elongate body includes an electrode array provided along a length thereof configured to deliver energy to specific target sites within the nasal passage and nasal cavity in conjunction with neuromodulation provided by the multi-segment end effector.

Abstract: A laser system may include a controller configured to direct a plurality of temporally spaced-apart electrical pulses to a device that optically pumps a lasing medium, and a lasing medium configured to output a quasi-continuous laser pulse in response to the optical pumping. The plurality of temporally spaced-apart electrical pulses may include (a) a first electrical pulse configured to excite the lasing medium to an energy level below a lasing threshold of the lasing medium, and (b) multiple second electrical pulses following the first electrical pulse. The quasi-continuous laser pulse is output in response to the multiple second electrical pulses.

Abstract: Apparatuses, systems, and methods for more accurate remote monitoring of a user's body to stabilize the user during fall events and to thereby prevent the user from falling. In some embodiments, a wearable device comprising a power source, one or more sensors configured to monitor a user's COG (COG), at least one plurality of electrodes, a communications interface and a control device is provided. The wearable device is configured to apply electrical pulses according to defined electrical pulse stimulation protocols via the electrodes to target muscle groups of the user's body, causing those target muscle groups to contract and thereby stabilize the user's body during a fall event.

Abstract: An electronic device includes a biological information acquirer that acquires biological information of a target; an error factor detector that detects a factor that causes an error in the biological information; a display; and at least one processor. The error factor detector includes a motion detection sensor that detects a direction of motion of the electronic device, and the processor is that determines whether the factor is detected, based on the direction of the motion of the electronic device; and to cause, when the processor determines that the factor is detected, the display not to display the biological information acquired by the biological information acquirer, or to cause the biological information acquirer to stop acquisition of the biological information, in a period determined based on a timing when the factor is detected.

Abstract: A system and method used to deliver a percutaneous ventricular assist device (pVAD) or other cardiac therapeutic device to a site within the heart, such as a site at the aortic valve. A flexible device is percutaneously introduced into a vasculature of a patient and positioned to run from a femoral vein, through the heart via a transseptal puncture, and to a femoral artery. The venous-side end of the flexible device is withdrawn out the venous vasculature superior to the heart, and a pVAD is secured to the flexible device. The pVAD is pushed in a distal direction while the arterial-side end of the flexible device is pulled in the proximal direction to advance the pVAD to the target site. A left ventricle redirector aids in orienting the pVAD and preventing migration of the flexible member towards delicate structures of the heart during advancement of the pVAD.

Abstract: An apparatus for creating resonant standing waves in biological tissue, in particular in the treatment of medical conditions, comprising at least one applicator for application to biological tissue and a drive unit for driving the at least one applicator simultaneously with AM modulated and FM modulated carrier signals in order to create resonant standing waves in the tissue.

Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system herein can include an electric field generating circuit configured to generate one or more electric fields, and control circuitry. The system can include one or more electrodes disposed on a first stimulation lead to deliver the electric fields to a site of a cancerous tumor within a patient and one or more electrodes disposed on a second stimulation lead to deliver the electric fields to the site of a cancerous tumor within a patient. The first and second stimulation leads can be configured to be implanted on or about a duodenum. The electric field generating circuit can generate electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

Abstract: Foley type catheter embodiments for sensing physiologic data from a urinary tract of a patient are disclosed. The system includes the catheter and a data processing apparatus and methods for sensing physiologic data from the urinary tract. Embodiments may also include a pressure sensor having a pressure interface at a distal end of the catheter, a pressure transducer at a proximal end, and a fluid column disposed between the pressure interface and transducer. When the distal end is residing in the bladder, the pressure transducer can transduce pressure impinging on it into a chronological pressure profile, which can be processed by the data processing apparatus into one or more distinct physiologic pressure profiles, for example, peritoneal pressure, respiratory rate, and cardiac rate. At a sufficiently high data-sampling rate, these physiologic data may further include relative pulmonary tidal volume, cardiac output, relative cardiac output, and absolute cardiac stroke volume.

Abstract: A system and method of modeling flow of a vasculature in near real-time, is described. A vessel segment of the vasculature is modeled by a reduced order model, and a remainder of the vasculature is modeled by a 0D model. The reduced order model is generated using boundary conditions generated by a 0D model of the entire vasculature. Moreover, the reduced order model of the vessel segment and the 0D model of the remainder of the vasculature can be coupled to simulate flow that can be compared to actual flow measurements to personalize the 0D model of the remainder of the vasculature for a patient. Accordingly, a physician can update parameters of the personalized vascular system model to predict the effects of treatment protocols, including exercise or therapeutic substances, on the patient. Other embodiments are also described and claimed.

Abstract: A surgical system corrects a surgical parameter based on a nomogram specific for a refractive laser surgery system to provide a nomogram-based corrected surgical parameter; stores the surgical parameter and the nomogram-based corrected surgical parameter as data for a patient or for one or both eyes of the patient; and compares the surgical parameter and nomogram-based corrected surgical parameter to generate a graphical representation of the surgical parameter, a target outcome parameter associated with the surgical parameter, or both, and the nomogram-based corrected surgical parameter, to generate a warning based on a comparison of the nomogram-based corrected surgical parameter to the surgical parameter or an absolute value, or both.

Abstract: Systems and methods to detect pneumonia in cardiovascular patients are disclosed, including receiving physiologic information of a patient from an ambulatory medical device (AMD), the physiologic information comprising respiration information of the patient, and determining a pneumonia score of the patient using the received respiration information.

Abstract: A method of modulating neural activity using a combination of electrical and optical stimulation transmitted via a gold nanoparticle covered nanoelectrode is presented. The combination of short-duration green visible light optical pulses with the complementary sub-threshold level electric current pulses are capable of producing action potentials in neurons. Cells were found to have a greater than a 5× survival rate using this hybrid stimulation method as compared to pure plasmonic/optical stimulation. The cell stimulation success rate was 3× greater with hybrid stimulation.

Abstract: Physiological variables, metrics, biomarkers, and other data points can be used, in connection with a non-invasive wearable device, to screen for, and predict, mental health issues and cognitive states. In addition to metrics such as heart rate, sleep data, activity level, gamification data, and the like, information such as text message and email data, as well as vocal data obtained through a phone and/or a microphone, may be analyzed, provided user authorization. Applying predictive modeling, one or more of the monitored metrics can be correlated with mental states and disorders. Identified patterns can be used to update the predictive models, such as via machine learning-trained models, as well as to update individual event predictions. Information about the mental state predictions, and updates thereto, can be surfaced to the user accordingly.

Abstract: Disclosed systems include mobile ECG sensors, systems and methods. Some embodiments provide ECG sensors in a packaging-label form factor that allows a user to contact two electrically isolated electrodes on an exterior of a product packaging to measure heart electrical signals for a Lead I ECG.