Abstract: The reaction of a lipase upon a fatty acid is effected by an improved method which comprises bringing the lipase bonded at multiple points to an anion-exchange residue or a carrier and a carrier having a free anion-exchange group admixed therewith into contact with a reaction mixture containing an oily substance including the fatty acid and a water-soluble substance thereby forming an oily product and a water-soluble product in the reaction mixture and subsequently separating the two reaction products.

Abstract: The compounds of this invention are anilides represented by the formula: ##STR1## wherein: R.sub.1 and R.sub.2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a ##STR2## group wherein n, m and p are independently an integer of from 1 to 8 provided that n+m+p is equal to or less than 10; X is thio, sulfinyl or sulfonyl; Alk is straight or branched chain lower alkylene; R.sub.3 is hydrogen or lower alkyl; and R.sub.4 is phenyl or substituted phenyl. The compounds of the present invention are useful in the treatment of inflammation, allergy and hypersensitivity reactions and other disorders of the immune system.

Abstract: A process for the preparation of ascorbic acid-2-phosphate, which comprises reacting ascorbic acid or araboascorbic acid with a phosphate donor other than ATP in an aqueous medium in the presence of an effective amount of an enzyme derived and capable of preferentially catalyzing the enzymatic phosphorylation in the 2-position of ascorbic acid or araboascorbic acid by said phosphate donor, and recovering the resultant ascorbic acid-2-phosphate from the reaction solution.

Abstract: A novel cyclobutenedione derivative is provided, represented by formula (I): ##STR1## wherein Ar represents ##STR2## wherein R.sub.1 represents a CH.sub.3 group or a C.sub.2 H.sub.5 group; R.sub.2 represents a C.sub.2 H.sub.5 group, a C.sub.3 H.sub.7 group, a HOC.sub.2 H.sub.4 group, a CH.sub.3 OC.sub.2 H.sub.4 group or a CH.sub.3 group; R.sub.3 represents an alkyl group; Z represents O or S; and R.sub.4 and R.sub.5 each represents an alkyl group, and R.sub.0 represents ##STR3## wherein C* represents an asymmetric carbon atom. A process for preparing a cyclobutenedione derivative represented by formula (I) which comprises reacting a cyclobutenedione derivative represented by formula (II) with an amino acid derivative represented by formula (III): ##STR4## wherein Ar represents ##STR5## wherein R.sub.1 represents a CH.sub.3 group or a C.sub.2 H.sub.5 group, R.sub.2 represents a C.sub.2 H.sub.5 group, a C.sub.3 H.sub.7 group, a HOC.sub.2 H.sub.4 group, a CH.sub.3 OC.sub.2 H.sub.4 group or a CH.sub.3 group; R.

Abstract: The invention relates to novel N-[3-halo-4-(hexafluoropropoxy)-5-trifluoromethyl]phenyl-N'-benzoylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or halogen and R.sub.2 and R.sub.3 are halogen, to a process and intermediate for the preparation of these compounds, and to compositions containing them for use in pest control, in particular for controlling insects and representatives of the order Acarina that attack plants and animals. The novel compounds exhibit in particular larvicidal activity.

Abstract: The present invention relates to a process for the n-alkylation and n-allylation of anilines by bringing the aniline into contact with an alkylating or allylating agent in an organic solvent in a homogeneous liquid phase in the presence of an onium ion and a stoichiometric amount of a non-quaternizable base.

Abstract: A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present,a) about 20 to about 40 mole % DETA,b) about 15 to about 60 mole % EDA (net generated),c) about 5 to about 18 mole % AEEA,d) about 3 to about 25 mole % of the combination of PIP, AEP and HEP,e) less than about 1 to about 5 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polyamines,g) a DETA to AEEA mole ratio greater than about 1.35, andh) an EDA to DETA mole ratio less than 2.60,and the process of manufacturing it which comprises feeding hydrogen, ammonia, MEA and EDA, preferably provided from a recycle stream, to a reaction zone containing a fixed bed of a reductive amination catalyst in a tubular reactor, wherein the hydrogen comprises about 1 to about 30 mole percent of the feed in the reaction zone, the mole ratio of EDA to MEA is greater than 0.

Abstract: A continuously generated alkyleneamines producers composition comprising based on 100% of the moles of the compostion and exclusive of any MEA and water present,a) about 15 to about 35 mole % DETA,b) about 15 to about 55 mole % EDA (net generated),c) about 10 to about 35 mole % AEEA,d) about 3 to about 25 mole % of the combination of PIP, AEP and HEP,e) about 3 to about 10 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polyamines, andg) a DETA to AEEA mole ratio greater than about 0.77 to less than 1.35,and the process of producing the same, which comprises feeding hydrogen, ammonia, MEA and EDA, preferably provided from a recycle stream, to a reaction zone containing a fixed bed of a reductive amination catalyst in a tubular reactor, wherein the hydrogen comprises about 10 to about 50 mole percent of the feed in the reaction zone, the mole ratio of EDA to MEA is less than about 0.

Abstract: The present Application discloses pesticidally active compounds of the formula (I):Q Q.sup.1 CR.sup.2 =CR.sup.3 CR.sup.4 =CR.sup.5 C (.dbd.X) NHR.sup.1or a salt thereof, wherein Q is an monocyclic aromatic ring. or fused bicyclic ring system of which at least one ring is aromatic containing 9 or 10 atoms of which one may be nitrogen and the rest carbon each optionally substituted, or Q is a dihalovinyl group or a group R.sup.6 --C.tbd.C-- where R.sup.6 is C.sub.1-4 alkyl, tri C.sub.1-4 alkylsilyl, halogen or hydrogen; Q.sup.1 is a 1,2-cyclopropyl ring optionally substituted by one or more groups selected from C.sub.1-3 alkyl. halo, C.sub.1-3 haloalkyl, alkynyl, or cyano; R.sup.2,R.sup.3, R.sup.4 and R.sup.5 are the same or different with at least one being hydrogen and the others being independently selected from hydrogen, halo. C.sub.1-4 alkyl or C.sub.1-4 haloalkyl; X is oxygen or sulphur; and R.sup.1 is selected from hydrogen and C.sub.

Abstract: An effective delayed-action insecticide for use against the imported fire ant (IFA), as well as against infestations of other insects. The insecticide consists of an oil insoluble surfactant, preferably an anionic fluorochemical surfactant, as the active ingredient. The insecticide further consists of a carrier, which is a source of food for the IFA or other insect. This carrier is impregnated with the anionic fluorosurfactant to provide a toxic bait. In a preferred embodiment, the insecticide contains 0.3 to 0.5% by weight anionic fluorosurfactant; and a member selected from the group comprising dried yellow corn meal, corn grit, crushed wheat, and cracked wheat in a concentration of 94.7 to 94.5% by weight, as the carrier. Soybean oil, in a concentration of 5.0% by weight, is preferably applied as an attractant. A method for formulating the insecticide by dissolving the anionic fluorosurfactant in a solvent, such as acetone or methanol, and mixing the resulting solution with the carrier, is also disclosed.

Abstract: A water-soluble reactive dye of the formula:D.sup.1 --Z.sup.1 --NR.sup.1 --T--NR.sup.2 --Z.sup.2 --D.sup.2 (1)whereineach of D.sup.1 and D.sup.2, independently, represents the radical of a water-soluble chromophoric compound,each of Z.sup.1 and Z.sup.2, independently, represents a triazine or pyrimidine residue carrying an atom or group imparting fibre-reactivity to the dye,R.sup.1 represents an optionally substituted alkyl radical,R.sup.2 represents hydrogen or an optionally substituted alkyl radical, andT represents a 1,3- or 1,4-phenylene radical which may carry one or more substituents selected from halogen, alkyl, alkoxy, acylamino, nitro and carboxy.

Abstract: A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present,a) about 14 to about 20 mole % DETA,b) about 45 to about 75 mole % EDA (net generated),c) about 4 to about 10 mole % AEEA,d) about 3 to about 25 mole % of the combination of PIP, AEP and HEP,e) about 0.5 to about 5 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polymines,g) an EDA to DETA mole ratio greater than about 2.60,h) a DETA to AEEA mole ratio greater than about 1.35, andi) an EDA to AEEA mole ratio greater than about 8,and a process of manufacturing it which comprises feeding hydrogen, ammonia, MEA and EDA, preferably provided from a recycle stream, to a reaction zone containing a fixed bed of a reductive amination catalyst in a tubular reactor, wherein the hydrogen comprises about 1 to about 30 mole percent of the feed in the reaction zone, the mole ratio of EDA to MEA is less than about 0.

Abstract: Disclosed are a novel fluoran compound represented by the formula (I): ##STR1## and a heat-sensitive recording paper which is obtained by using the fluoran compound as a chromogenic compound and is excellent in preserving stability.

Abstract: Carbonyl derivatives of 4-pentafluorophenoxypiperidines and methods for treating convulsions, depression, and hypertension utilizing compounds or compositions thereof are disclosed.

Abstract: Cyclohexenone oxime ethers ##STR1## where R.sup.1 is alkyl;A is substituted or unsubstituted alkylene or alkenylene, where methylene is replaced by an oxygen atom, a sulfur atom, a sulfoxyl group, a sulfonyl group or --NR.sup.a --,Z is phenyl or a 5- or 6-membered heteroaromatic structure;X is substituted or unsubstituted amino, nitro, cyano, halogen, alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -haloalkoxy, carboxyl, C.sub.1 -C.sub.4 -alkoxycarbonyl, substituted or unsubstituted benzyloxycarbony or phenyl;n is 0 to 3, or 1 to 5 where X is halogen;R.sup.

Abstract: The present invention relates to a process for the N-alkylation and N-allylation of an aniline by bringing the aniline into contact with an alkylating or allylating agent in an organic solvent in a homogenous liquid phase in the presence of an iodide and a stoichiometric amount of non-quaternizable base.

Abstract: A branched chain polyalkylene polyamine ("PAPA") having plural amine groups, including a secondary amine group intermediate terminal primary amine groups one of which is hindered, and having at least two carbon atoms between each group, is selectively reductively alkylated with a ketone. The reaction provides a convenient method for selectively reductively alkylating a PAPA having a hindered primary amine group, the method comprising contacting the PAPA with hydrogen and the ketone in the presence of a catalytically effective amount of a Group VIII metal on a catalyst support, at a pressure in the range from about 500-1000 psi and a temperature in the range from about 50.degree. C. to about 200.degree. C. for a period of time sufficient to preferentially alkylate the unhindered amine primary terminal amine group. The alkylation proceeds essentially without alkylating either the sterically hindered terminal primary amine group or the intermediate unhindered secondary amine group.

Abstract: Compounds of the structure ##STR1## where M is a pharmaceutically acceptable cation or a metabolically cleavable group, R is alkyl, cycloalkyl or --NR.sup.1 R.sup.2, where R.sup.1 and R.sup.2 are hydrogen, alkyl, cycloalkyl or alkanoyl, and A is optionally substituted alkyl, cycloalkyl, carbocyclic aryl, benzo[b]furyl, thienyl, or benzo[b]thienyl are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.

Abstract: A method for the preparation of optically active 3-hydroxypyrrolidine derivatives is disclosed, which comprises the steps of: hydrolyzing a mixture of (R)- and (S)-N-benzyl-3-acyloxypyrrolidine by the use of microorganisms or enzymes with stereospecific esterase activity; and separating optically active N-benzyl-3-hydroxypyrrolidine and optically active N-benzyl-3-acyloxypyrrolidine from the hydrolysate obtained in the foregoing step.

Abstract: Compounds of the formula (I): ##STR1## wherein R.sup.1 is hydrogen or fluoro and R.sup.2 is hydrogen or C1-6 alkyl and salts thereof are described as agents for the treatment of obesity and related conditions. Processes for their preparation and intermediates are described.