Abstract: A surgical system for use with a surgical robot is disclosed. The surgical system comprises a housing comprising an attachment portion configured to be mounted to the surgical robot and a plurality of rotary drive members configured to transmit rotary motions. The surgical system further comprises an elongate shaft, an end effector, an articulation joint, a first closure system, a second closure system, and a camming member. The end effector comprises a first jaw, a second jaw, a removable fastener cartridge, and a drive screw configured to rotate in response to a rotary motion. The first closure system is configured to actuate a cable in response to a rotary motion. The second closure system comprises a coupling member operably attached to the drive screw and configured to move the first jaw toward a clamped position when actuated. The camming member is configured to eject fasteners from the fastener cartridge.