Abstract: A system and method for flushing stale data from a read prefetch buffer of a PCI bus system which transfers data in the form of data streams of contiguous blocks. The PCI bus system comprises a channel adapter at one PCI bus that issues read commands, a data source coupled to a second PCI bus, and a prefetch buffer that prefetches the blocks of read data. A prefetch counter posts the remaining number blocks to be read and transferred, posting the prefetch count at a storage location of a storage memory mapped to a prefetch location in the prefetch buffer. The prefetch count is written to the storage location by a prefetch count write command. The system for flushing stale data from the prefetch buffer comprises a key detector for sensing an unique identifier of the prefetch count write command.