Patents Examined by Christina Marchetti Bradley
  • Antagonist peptides to VEGF receptor Flt-1
    Patent number: 7250395
    Abstract: The present invention provides a polypeptide or a pharmacologically acceptable salt thereof comprising one or more, identical or different, amino acid sequences of A-W—H—X1-D-X2-X3-X4-W—W—X5-X6-X7-X8-B (the meaning of each symbol in the formula is defined in the description) and a pharmaceutical composition for treating an angiogenic disease such as a solid tumor comprising said polypeptide. The present invention also relates to a polynucleotide encoding the above-mentioned polypeptide and use of the polynucleotide in gene therapy.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: July 31, 2007
    Assignee: Beijing Institute for Cancer Research
    Inventors: Chengchao Shou, Hetian Lei, Ping An, Jian Wu, Lin Meng, Xiaoying Liu
  • Statine derivatives for the treatment of Alzheimer's disease III
    Patent number: 7238774
    Abstract: The invention relates to a compound of the formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are defined as in the specification and claims and to its use for treating or preventing Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: July 3, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stefan Peters, Klaus Fuchs, Christian Eickmeier, Werner Stransky, Cornelia Dorner-Ciossek, Sandra Handschuh, Herbert Nar, Klaus Klinder, Marcus Kostka
  • Protective factors against inflammation, burns and noxious stimuli
    Patent number: 7238656
    Abstract: Peptide factors isolated from skin following exposure to chemical or thermal injury and treatment with iodine preparations are capable of reducing or ameliorating the extent of injury when administered to other animals. Specific peptides, including fragments of histone H2A and fibrinopeptide A, and preferred derivatives of these peptides are disclosed. The extracts, peptides and pharmaceutical compositions according to the invention are useful for the preparation and treatment of inflammatory conditions and exposure to noxious stimuli.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: July 3, 2007
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Uri Wormser