Abstract: An eye drop bottle storage unit for eye drop administration compliance includes a memory, a processor, and one or a plurality of eye drop bottle pods, where each eye drop bottle pod of the one or said plurality of eye drop bottle pods is configured to hold an eye drop bottle, and comprises one or a plurality of sensors. The memory is configured to store data of an eye drop administration regime of a subject. The processor is configured to receive signals from the one or said plurality of sensors of each eye drop bottle pod, and to determine from the received signals whether the subject administered eye drops into eyes of the subject from each eye drop bottle respectively held in each eye drop bottle pod of the one or said plurality of eye drop bottle pods in accordance with the eye drop administration regime data.

Abstract: A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: A breast pump system is provided with a suction tubing and a milk tubing, wherein the suction tubing and milk tubing each have first and second ends, and comprise a unitary tube structure. The system includes a first connector that has a first portion for coupling to a breast pump and the suction tubing, and a second portion for coupling to a milk bottle and the milk tubing. The system also includes a second connector that has a first portion coupled to a suction port of a breast shield and the suction tubing, and a second portion coupled to a breast milk collecting port and the milk tubing. A breast shield system with a flexible diaphragm and a cover is provided that may be coupled to the breast pump system. A dual suction path filter cartridge is also provided.

Abstract: A fluid mixing device for mixing a first injection fluid and a second injection fluid includes a first fluid inlet, a second fluid inlet, a mixing chamber in fluid communication with the first and second fluid inlets, and an outlet port in fluid communication with the mixing chamber. The first fluid inlet is configured to conduct the first injection fluid in a first direction and has a first redirecting surface. The second fluid inlet is configured to conduct the second injection fluid in a second direction along a different axis from the first direction and has a second redirecting surface. The mixing chamber is configured to mix the first injection fluid and the second fluid together. The mixture of the first injection fluid and the second injection fluid exits the fluid mixing device via the outlet port.

Abstract: A method and device for delivering medications that includes a syringe body, a cartridge nest with an application tip, a plunger actuator, and an electronic lock subassembly adapted for preventing administration of the medication until specific conditions are met. The medicine cartridge may comprise a form of a digital security key to prevent the device from administering medication unless specific configurations and conditions are met. The device may further be adapted with pre-programmed information and may be used with a smartphone, tablet, or computer application. The electronic lock subassembly will only permit the administration of medicine when the patient and/or administrator is verified via facial and voice recognition, biometric identifier, or other unique information. Upon proper permission, the device may be used to administer medicine, including injecting medicine into the nasal cavity of a patient.

Abstract: Method and system for controllably administering and/or withdrawing fluid from a patient. In one embodiment, the system may include an infusion needle, a pump adapted to be operably coupled to the infusion needle for creating fluid flow through the infusion needle, and a hands-free switch for activating and/or deactivating the pump.

Abstract: Delivery devices, systems, and methods may be configured to define a barrier region at a treatment site to deliver one or more therapeutic materials. A device for delivering one or more therapeutic materials to a treatment site may include a body; one or more members that are movable with respect to the body and that are configured to define a barrier region at the treatment site; and one or more delivery lumens configured to deliver one or more therapeutic materials to the barrier region.

Abstract: A lactation system is disclosed. Embodiments include at least one extraction mechanism including a compression mechanism and a collection mechanism, and a controller. The compression mechanism can include a plurality of manipulable members, each operably coupled to an actuator and arrangeable circumferentially about a breast of a user such that each member can be actuated to selectively apply pressure to a region of the breast. The collection mechanism can be removably coupleable to the compression mechanism and can comprise a storage compartment to receive and store milk The controller can be operably coupleable to the actuators to cause the members to move according to a movement pattern which can be configured to stimulate the breast to induce the flow of milk from the breast and modulated based on sensor feedback. A wearable garment with an inner structure can be removably coupled to the extraction mechanism. An outer cover can be arrangeable to conceal the extraction mechanism.

Abstract: An object of the present invention is to provide an anti-adhesive/anti-clogging and/or color marked/tinted micro-capillary tube (microtube), microneedle, or micropipette. Typically, the color/tint will be selected such that the tip of the microneedle or micropipette is in contrast (e.g., visually) to the biological material. The tint/color may be selected to contrast the stained biological material. In some aspects, the color mark comprises nanoparticles that are modified by adding a non-adhesive coating/material that minimizes protein adhesion/adsorption. The microtubes and/or micropipettes may be treated with an anti-clogging reagent and an anti-adhesive reagent to prevent or reduce clogging and adhesion of the micropipette or microneedle to biological materials. The microtubes and/or micropipettes may be formed using additive printing processes and additive manufacturing techniques or from micropipette and microneedle pullers.

Abstract: A medical suctioning, pressure relief valve having a housing having a central fluid passage way, a first suction tubing connector configured to connect suction tubing to the central fluid passage way, a second suction tubing connector configured to connect suction tubing to the central fluid passage way, and a one-way internal pressure relief valve configured to allow ambient air into the central passage way when a set negative pressure is reached within the central passage. A method of suctioning a fluid from a patient using the medical suctioning, pressure relief valve.

Abstract: A resuscitation management system may include a first accelerometer and a second accelerometer mounted on opposite sides of a resuscitation bag of a manual resuscitation device. The resuscitation management system may include a processing unit that may be configured to receive the measured acceleration vectors from the first accelerometer and the second accelerometer and then subtract the measured acceleration vectors from each other to obtain a resultant acceleration vector representing an acceleration magnitude and a spatial acceleration direction of compression/decompression of the resuscitation bag. The processing unit may then be configured to calculate the breathing parameters based at least in part on the acceleration magnitude and the spatial acceleration direction of compression/decompression of the resuscitation bag.

Abstract: Guide extension catheters and related methods are disclosed. A guide extension catheter can comprise an elongate tube member and a lumenless push member. The push member can be eccentrically coupled to the tube member for slidably positioning the tube member within and partially beyond a distal end of a guide catheter. At least a proximal end portion of the push member can include a cross-section defined by an arcuate first surface and an opposing second surface. The first surface can engage an inner wall surface of the guide catheter along an arc length, and the second surface can be spaced furthest from the first surface at its center point. The first surface can have the same or substantially the same radius of curvature as the guide catheter's inner wall surface, and the second surface can be flat or substantially flat. This configuration of the push member can provide an advantageous blend of stiffness and flexibility, as well as space conservation through the guide catheter.

Abstract: An infusion system for subcutaneous delivery of a fluid to a subject is disclosed. The infusion system comprises a source of a fluid; a fluid delivery system; a first fluid conduit in fluid communication with the source of the fluid and the fluid delivery system; a fluid injection device configured to be inserted into the skin of a subject for delivering the fluid to the subject; a second fluid conduit in fluid communication with the fluid delivery system and the fluid injection device; and a support frame attached to the source of the fluid and the fluid delivery system, wherein the support frame is configured to mount the source of the fluid and the fluid delivery system on a region of a head of the subject. The fluid delivery system moves the fluid from the source of the fluid, through the first fluid conduit, through the second fluid conduit, and through the fluid injection device.

Abstract: A treatment method is disclosed capable of reducing the burden on a patient and enhancing the effect of killing tumor cells. The method includes administering an antibody-photosensitive substance into a vein; inserting an endoscope from a mouth, a nose, or an anus and bringing the endoscope to a vicinity of a tumor after the administering of the antibody-photosensitive substance into the vein; placing an optical fiber into the tumor or in the vicinity of the tumor; irradiating at least one of the tumor, the vicinity of the tumor, or a regional lymph node with a first near-infrared ray by the optical fiber; and irradiating the antibody-photosensitive substance bound to a tumor cell membrane in the tumor cell with a second near-infrared ray after the irradiating with the first near-infrared ray, the second near-infrared ray having a shorter wavelength than that of the first near-infrared ray.

Abstract: An integrated breast pump includes a housing, a triple valve integrated with the housing, a breast adapter, a negative pressure generation device, a negative pressure transmission element and an one-way valve. The triple valve includes a liquid inlet, a liquid outlet and a negative pressure port. The breast adapter includes a liquid guiding outlet and is detachably connected with housing. The liquid guiding outlet communicates with the liquid inlet. The negative pressure generation device includes a pumping port and is configured for providing negative pressure periodically. The negative pressure generation device is detachably connected with housing, and the pumping port is disposed towards the negative pressure port. The negative pressure transmission element is disposed in the negative pressure port and communicates with the pumping port. The negative pressure transmission element is configured for generating deformation periodically according to the negative pressure.

Abstract: The present disclosure discloses an assembling-facilitated breast pump, including, a main body, a milk flowing member and a breast cover; the main body includes a suction assembly and a milk storage container; the suction assembly is detachably connected to the milk storage container a negative pressure tank is arranged in the milk storage container; the suction assembly is communicated to the negative pressure tank; the entire main body is hemispherical; the milk flowing member is hermetically plugged, into the negative pressure tank; one end of the milk flowing member is provided with an opening; a side of the milk flowing member close to the opening is provided with a milk outlet; the milk outlet is used for being communicated to an accommodating cavity of the milk storage container; and a narrow end of the breast cover is hermetically plugged to the opening.

Abstract: A double-balloon catheter device for gastrointestinal anastomosis. The double-balloon catheter device for gastrointestinal anastomosis includes a liquid injection assembly, a double-balloon assembly, and a supporting device (15) connecting the liquid injection assembly and the double-balloon assembly. The liquid injection assembly includes a first balloon liquid injection connection port (2), a guide wire connection port (3), and a second balloon liquid injection connection port (4). The double-balloon assembly includes a double-balloon catheter device (5), and includes a first balloon (6) and a second balloon (7) that can expand-and that are respectively disposed on the two ends of the double-balloon catheter device (5). The double-balloon catheter device (5) is provided with a first balloon liquid injection channel (51), a guide wire channel (52), and a second balloon liquid injection channel (53).

Abstract: A breast pump assembly is disclosed.

Abstract: Shown is a simple, reliable manner of monitoring a process of expelling a variable dose of medicament from an injection device by analyzing mechanical feedback of the injection device with reduced requirements on signal data memory space and processing power. Specific measurand and mechanical user feedback sensor configurations enable sensor signal data from which individual dosage units of expelled drug are identifiable at moderate sampling rates. Preferred configurations include a force sensor adapted to measure an axial force component as applied to the device by a user pressing a proximal injection button, and a direction sensor adapted to measure an azimuth angle of an orientation of the device. The specific measurands, or process quantities observed, relate to feedback means of the device including a resilient element that produces a number of successive mechanical feedback events proportionate to a dose or quantity of drug expelled from a medicament reservoir.