Abstract: Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.
Type:
Grant
Filed:
September 19, 2016
Date of Patent:
February 19, 2019
Assignee:
Advanced BioNutrition Corp.
Inventors:
Moti Harel, Qiong Tang, Trisha Rice, Kimberly Jennings, Brian Carpenter, Roger Drewes, Elizabeth Raditsis, January Scarbrough
Abstract: Disclosed are methods of enhancing plant growth, comprising treating plant seed or the plant that germinates from the seed with an effective amount of at least two lipo-chitooligosaccharides, wherein upon harvesting the plant exhibits at least one of increased plant yield measured in terms of bushels/acre, increased root number, increased root length, increased root mass, increased root volume and increased leaf area, compared to untreated plants or plants harvested from untreated seed.
Abstract: In alternative embodiments, the invention provides products (articles) of manufacture comprising nanostructures such as nanotubes having a surface comprising tantalum. In alternative embodiments, products of manufacture of the invention include nanostructures, e.g., nanotubes, nanowire, nanopore, and the like comprising a surface layer of tantalum. In alternative embodiments, products or articles of manufacture of the invention are bioimplants, and the tantalum-surface-coated nanostructures of the invention provide increased bioactivity and bone forming ability. In alternative embodiments, products or articles of manufacture of the invention, e.g., bioimplants, comprising the tantalum-surface-coated nanostructures of the invention are used for in vitro, ex vivo and in vivo testing, implants, biomedical devices and therapeutics.
Type:
Grant
Filed:
February 7, 2013
Date of Patent:
December 11, 2018
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Abstract: Provided is a method for increasing hair shaft diameter, the method including applying a hair care composition to a region of the hair, wherein the hair care composition includes from about 0.01% to about 10% of hops, wherein the hops is first extracted in glycerin; and from about 0.1% to about 10% of a rheology modifier.
Abstract: DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.
Type:
Grant
Filed:
April 29, 2015
Date of Patent:
November 6, 2018
Assignees:
Omthera Pharmaceuticals, Inc., Chrysalis Pharma AG
Inventors:
Timothy J. Maines, Bernardus N. Machielse, Bharat M. Mehta, Gerald L. Wisler, Michael H. Davidson, Peter Ralph Wood
Abstract: The invention relates to microparticles comprising a matrix formed by casein and chitosan, and probiotic bacteria; said matrix protects said probiotic bacteria during (i) processing, (ii) storage and (iii) transit through the gastrointestinal tract, prolonging their lifetime. The present invention also relates to the method for obtaining the microparticles and to the products and compositions incorporating them.
Type:
Grant
Filed:
July 5, 2013
Date of Patent:
October 30, 2018
Assignees:
CENTRO NACIONAL DE TECNOLOGÍA Y SEGURIDAD ALIMENTARIA, LABORATORIO DEL EBRO, UNIVERSIDAD DE NAVARRA
Inventors:
Maite Agüeros Bazo, Irene Esparza Catalán, Carlos Gamazo De La Rasilla, Carolina González Ferrero, Carlos Javier González navarro, Juan Manuel Irache Garreta, Rebeca Peñalba Sobrón, Ana Romo Hualde, Raquel Virto Resano
Abstract: What are described are herbicidal compositions comprising active ingredients from the group of the N-(1,3,4-oxadiazol-2-yl)arylcarboxamides and further herbicides and optionally safeners. These herbicidal compositions are particularly suitable for use against harmful plants in crops of useful plants.
Type:
Grant
Filed:
October 22, 2014
Date of Patent:
October 30, 2018
Assignee:
BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventors:
Arnim Koehn, Christian Waldraff, Elmar Gatzweiler, Klaus Trabold, Hubert Menne, Hartmut Ahrens, Simon Doerner-Rieping, Ralf Braun, Ines Heinemann
Abstract: An insecticidal polymer matrix containing Piperonyl Butoxide (PBO) and deltamethrin (DM), wherein the ratio between the content of PBO and the content of DM in terms of weight is higher than 3.
Type:
Grant
Filed:
December 8, 2014
Date of Patent:
October 30, 2018
Assignee:
Vestergaard SA
Inventors:
Mikkel Vestergaard Frandsen, Michael Stanley Pedersen, Matthieu Zellweger, Sebastien Gouin, Sicco Dirk Roorda, Thi Quynh Chi Phan
Abstract: A sunscreen composition comprised of one or more sunscreen active agents encapsulated in a cellulose derived capsule wherein the composition can contain one or more additional agents. A sunscreen composition can be mixed with a bodywash, shampoo, conditioner, lotion, gel, soap, cream, hand sanitizer, spray or mousse and can be used by an individual during their normal hygiene processes, such as during a shower or bath or while applying a body product to their skin or hair.
Abstract: A plurality of fibers or one-dimensional, two-dimensional, or three-dimensional fibrous structures are provided, having fibers from a first raw fiber material. The first raw fiber material contains unsubstituted or partially substituted polyvinyl alcohol and/or unsubstituted or partially substituted polyvinyl alcohol copolymer. The fibers can be crosslinked by tempering the fibers or fibrous structures, with the result that the fibers or the fibrous structure are configured to be gel, in particular hydrogel, fibers or fibrous structures and have excellent stability.
Type:
Grant
Filed:
July 29, 2011
Date of Patent:
October 9, 2018
Assignee:
Carl Freudenberg KG
Inventors:
Wiebke Schmitz, Julia Schmidt, Bernd Schlesselmann, Gunter Scharfenberger
Abstract: This invention relates to a wound dressing, particularly to a stimuli responsive wound dressing comprising a lyophilized hyaluronic acid (HA) hydrogel, and a plurality of devices embedded within said lyophilized hyaluronic acid hydrogel. Each of the plurality of devices including chitosan and hypromellose and may be formed as biofilms and/or electrospun fiber mats.
Type:
Grant
Filed:
June 5, 2015
Date of Patent:
September 25, 2018
Assignee:
University of the Witwatersrand, Johannesburg
Inventors:
Viness Pillay, Yahya Essop Choonara, Pradeep Kumar, Lisa Claire Du Toit, Naeema Mayet
Abstract: The invention pertains to a co-processed excipient composition suitable for tableting, said composition comprising at least one filler-binder, at least one disintegrant, and at least one lubricant which have been subjected to granulation together, and said composition partially or completely coated with lactose, preferably in crystalline form. The inventors have overcome the prejudice against the use of lubricants in tableting excipient compositions early in the tableting process. It was found that the alleged detrimental affects of the lubricant in terms of binding and disintegration could readily be controlled in a excipient composition wherein the lubricant is co-processed in the matrix, and the composition is provided with a lactose coat.
Abstract: The methods and devices disclosed herein are effective in the promoting the reattachment of delaminated cartilage to bone. The methods (and related devices) are effective in the removal of the acellular layer of the delaminated cartilage or effective in the indentation of the acellular layer of the delaminated cartilage thereby exposing the underlying chondrocyte cells and thereby allowing the promotion of the reattachment of the delaminated cartilage.
Type:
Grant
Filed:
November 8, 2013
Date of Patent:
August 28, 2018
Assignee:
Smith & Nephew, Inc.
Inventors:
Kelsey Jean Carvell, Ruth Cheng, Graham Smith, Drew Burdon, Paul Alexander Torrie
Abstract: The present invention relates to an anhydrous composition in cream form, characterized in that it comprises, in a cosmetically acceptable support: (a) at least one oily phase; (b) at least one non-emulsifying elastomeric organopolysiloxane; (b) a photoprotective system capable of screening out UV radiation; (c) at least one matting agent; (d) at least one non-silicone organic thickener for the oily phase, chosen from: (1) crystalline polymers, preferably semi-crystalline polymers, (2) fatty acid esters of dextrin, (3) hydrophobic-modified polysaccharides, (4) crystalline olefin copolymers, (5) crystalline polycondensates, (6) polymers of lipophilic polyamide type, (7) lipophilic polyureas and polyurethanes, (8) block polymers, (9) cholesterol-based liquid-crystal agents and mixtures thereof; the said composition not comprising any humectant.
Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
Type:
Grant
Filed:
April 18, 2013
Date of Patent:
June 12, 2018
Assignee:
SpecGX LLC
Inventors:
Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman, Sunil K. Battu, Eric A. Burge
Abstract: Substituted pyrimidinium compounds of the general formula (I) and their uses for combating animal pests The present invention relates to substituted pyrimidinium compounds of formula (I), to the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising such compounds. The invention also relates to methods and uses of these substituted pyrimidinium compounds and of compositions thereof, for combating and controlling animal pests. Furthermore the invention relates also to pesticidal methods of applying such substituted pyrimidinium compounds. The substituted pyrimidinium compounds of the present invention are defined by the following general formula (I): wherein X, Y, Z, R1, R2, A, A1 and A2 are defined as in the description.
Type:
Grant
Filed:
June 17, 2014
Date of Patent:
May 22, 2018
Assignee:
BASF SE
Inventors:
Joachim Dickhaut, Arun Narine, Swetlana Derksen, Nina Gertrud Bandur, Wolfgang Von Deyn, Raffael Koller, Jean-Yves Wach, Juergen Langewald, Nancy B. Rankl
Abstract: A method of making a gelled composition that includes combining water and an effervescent tablet in a vessel, the effervescent tablet including at least 200 mg gelatin and an effervescent couple that includes an acid and a base, heating an aqueous composition (e.g., in a microwave oven), optionally adding cold water to the heated composition, and chilling the composition for a period sufficient for the composition to form a gel.
Abstract: Process to elaborate a biostimulant based on seaweeds, comprising acid and alkaline treatment of the algae. The process comprises incorporating American Leonardite and subsequent spraying of product. The invention comprises the composition obtained and its use as germination promoter, root stimulator, among others.
Abstract: The present invention provides an infused carbohydrate based gel pad comprising: glucose polymer syrup, sugar, a hydrocolloid gelling agent, salt, acid, water and an infusing compound for oral transmucosal delivery wherein the gel pad (i) provides transmucosal delivery of active ingredients of the infusing compound into the bloodstream over a predetermined period of time; and (ii) possesses the property of adhesion to gum line tissue of an oral cavity and lack of adhesion to buccal tissue of the oral cavity. The present invention further provides a method of making the infused carbohydrate based gel.