Patents Examined by Daniel M. Sullivan
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Patent number: 7884245Abstract: The present invention provides a process for producing a hydrazone compound represented by the general formula (5): which comprises a step of condensing a hydrazine compound represented by the general formula (3): with a carbonyl compound represented by the general formula (4): without taking the hydrazine compound out of a reactor. According to the invention, the target hydrazone compound can be obtained in high quality and in a high yield without taking the hydrazine compound out of the reactor at all, the hydrazine compound being a reaction intermediate which is structurally unstable and has a fear of influencing safety of workers owing to its toxicity (mutagenicity).Type: GrantFiled: June 28, 2005Date of Patent: February 8, 2011Assignee: Hodogaya Chemical Co., Ltd.Inventors: Kiyokazu Takaso, Katsumi Abe, Atsushi Takesue
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Patent number: 7884248Abstract: A beneficial method for the manufacture of amino polyalkylene phosphonic acids, under substantial absence of hydrohalogenic acid, is disclosed. The method, in essence, is based on reacting narrowly defined ratios of phosphorous acid, an amine, a formaldehyde in presence of specific ranges of an acid catalyst having a pKa equal or inferior to 3.1. The inventive method is capable of yielding economically and quality operational/capacity advantages, in particular significantly reduced one-step cycle duration under exclusion, of corrosion disadvantages and also is environmentally friendly without requiring, in that respect, anything more than nominal capital expenditures.Type: GrantFiled: November 7, 2005Date of Patent: February 8, 2011Assignee: Thermphos Trading GmbHInventors: Patrick P. Notte, Isabelle Emmanuel Vanesse, Jan H. J. Van Bree
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Patent number: 7884225Abstract: The present invention relates to a process for the preparation of 3-chloropropyldimethylchlorosilane by hydrosilylation reaction in a reaction medium comprising dimethylhydrochlorosilane and allyl chloride, in the presence of a catalytically effective amount of di-?-chlorobis(?-1,5-cyclooctadiene)diiridium, the said process being characterized in that at least one auxiliary in the free or supported state selected from the group of compounds consisting of: (i) ketones, (ii) ethers, (iii) quinones, (iv) anhydrides, (v) unsaturated hydrocarbon compounds (UHC) having an aromatic nature and/or comprising at least one C?C double bond and/or at least one C?C triple bond, it being possible for these unsaturated bonds to be conjugated or nonconjugated, the said UHCs being linear or cyclic (mono- or polycyclic), having from 4 to 30 carbon atoms, having from 1 to 8 ethylenic and/or acetylenic unsaturations and optionally comprising one or more heteroatoms, (vi) and their mixtures, is added to the reaction medium, wiType: GrantFiled: July 16, 2008Date of Patent: February 8, 2011Assignee: Rhodia ChimieInventors: Nathalie Guennouni, Jean-Christophe Galland
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Patent number: 7884358Abstract: Disclosed are a novel aromatic enediyne derivative, an organic semiconductor thin film using the same, and an electronic device. Example embodiments pertain to an aromatic enediyne derivative which enables the formation of a chemically and electrically stable and reliable semiconductor thin film using a solution process, e.g., spin coating and/or spin casting, at about room temperature when applied to devices, an organic semiconductor thin film using the same, and an electronic device including the organic semiconductor thin film. A thin film having a relatively large area may be formed through a solution process, therefore simplifying the manufacturing process and decreasing the manufacturing cost. Moreover, it is possible to provide an organic semiconductor that may be effectively applied to various fields including organic thin film transistors, electroluminescent devices, solar cells, and memory.Type: GrantFiled: June 4, 2007Date of Patent: February 8, 2011Assignee: Samsung Electronics Co., Ltd.Inventors: Eun Jeong Jeong, Hyun Sik Moon, Jeong Il Park, Sang Yoon Lee
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Patent number: 7884237Abstract: Methanol carbonylation with improved aldehyde removal includes: (a) scrubbing light ends and aldehyde impurity from vent gas with an absorber solvent; (b) stripping absorbed light ends and aldehyde impurity from the absorber solvent to provide a vent-recovered light ends stream; (c) purifying the vent-recovered light ends stream to remove aldehyde impurity; and (d) recycling purified light ends from the vent-recovered light ends stream to the production system.Type: GrantFiled: November 7, 2008Date of Patent: February 8, 2011Assignee: Celanese International Corp.Inventor: Ronald D. Shaver
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Patent number: 7879818Abstract: Methods are disclosed for preparing novel biodegradable cross-linked nanoparticles based on covalently cross-linking modifications of hyaluronic acid. The final products of the present invention are stable in aqueous media, and may be used as detergents and as additives for pharmaceutical compositions for drug delivery, DNA carrier system and other applications. The nanoparticles made from the biopolymers of the present invention may also be used in controlled release applications, super-absorbent materials as well as biomaterials like enzyme immobilization.Type: GrantFiled: December 22, 2006Date of Patent: February 1, 2011Inventors: Janos Borbely, Tunde Rente, Magdolna Bodnar, Ildiko Schriffertne Denyicska
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Patent number: 7880040Abstract: Disclosed is a method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3CFnCHmXa-m??(I) to at least one compound of formula (II) CF3CZCHZ??(II). where each X is independently Cl, I or Br; each Z is independently H or F; n is 1 or 2; m is 1, 2 or 3, provided that when n is 1, m is 1 or 2; a is 2 or 3, and a-m?0. Certain embodiments include the step of reacting fluorinated C2 olefin, such as tetrafluoroethylene, with a C1 addition agent under conditions effective to produce a compound of formula (I).Type: GrantFiled: November 3, 2006Date of Patent: February 1, 2011Assignee: Honeywell International Inc.Inventors: Sudip Mukhopadhyay, Haridasan K. Nair, Hsueh S. Tung, Michael Van Der Puy, Rajiv R. Singh, Haiyou Wang, Robert C. Johnson, Rajesh K. Dubey
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Patent number: 7875739Abstract: Methods and kits for decomposing organophosphorus compounds in non-aqueous media at ambient conditions are described. Insecticides, pesticides, and chemical warfare agents can be quickly decomposed to non-toxic products. The method comprises combining the organophosphorus compound with a non-aqueous solution, preferably an alcohol, comprising metal ions and at least a trace amount of alkoxide ions. In a first preferred embodiment, the metal ion is a lanthanum ion. In a second preferred embodiment, the metal ion is a transition metal.Type: GrantFiled: March 5, 2007Date of Patent: January 25, 2011Assignee: Queen's University at KingstonInventors: R. Stanley Brown, Alexei A. Neverov, Josephine S. W. Tsang
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Patent number: 7875741Abstract: The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula Ia, where R1 and R1 is —OCH3, R2 and R2 is —OH; a process of preparation of compound of structural formula Ib, where R1 and R1 is —OCH3, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.Type: GrantFiled: June 26, 2007Date of Patent: January 25, 2011Assignee: Jawaharlal Nehru Centre for Advanced Scientific ResearchInventors: Tapas Kumar Kundu, Ruthrotha Selvi Bharatha Vikru, Hari Kishore Annavarapu, Mantelingu Kempegowda
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Patent number: 7875743Abstract: Manufacture a novel bis(formylphenyl)alkane according to General Formula (1), as well as a novel polynuclear phenol derived therefrom, by causing a bis(hydroxymethyl-hydroxyphenyl)alkane to react with hexamethylene tetramine in the presence of an acid and hydrolyzing the reaction product, and then using the obtained bis(hydroxy-formylphenyl)alkane as a direct material and causing this material to react with halogenated alkoxycarbonyl hydrocarbon in the presence of a base.Type: GrantFiled: October 3, 2007Date of Patent: January 25, 2011Assignee: Honshu Chemical Industry Co., Ltd.Inventor: Akira Yoshitomo
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Patent number: 7875747Abstract: In accordance with the disclosure, one aspect of the present application is directed to a dispersant compound comprising the reaction product of (i) a hydrocarbyl carbonyl compound, (ii) a polycarbonyl compound having at least three carbonyl acylating functions, and (iii) a primary amine moiety of a polyamine. Methods of making and methods of using the dispersant compound are also disclosed.Type: GrantFiled: October 10, 2006Date of Patent: January 25, 2011Assignee: Afton Chemical CorporationInventor: John T. Loper
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Patent number: 7875712Abstract: This invention provides caspase inhibitors of formula I: wherein Z is oxygen or sulfur; R1 is hydrogen, —CHN2, R, CH2OR, CH2SR, or —CH2Y; ?between R3 and R4 represents a single or double bond; Y is an electronegative leaving group; R2 is CO2H, CH2CO2H, or esters, amides or isosteres thereof; R3 is a group capable of fitting into the S2 subsite of a caspase enzyme; R4 is a hydrogen or C1-6 alkyl or R3 and R4 taken together form a ring; Ring A and Ring B are each heterocyclic rings, and R and R5 are as described in the specification. The compounds are effective inhibitors of apoptosis and IL-1? secretion.Type: GrantFiled: September 23, 2008Date of Patent: January 25, 2011Assignee: Vertex Pharmaceuticals IncorporatedInventors: Michael Mortimore, Andrew Miller, John Studley, Jean-Damien Charrier
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Patent number: 7873398Abstract: A saccharide-measuring fluorescence sensor substance including a copolymer of at least the following two compounds (I) and (II) is provided: (I) a fluorescent monomer compound represented by the following formula (1): formula (1) wherein: Q, Q? and D3 may be the same or different, may be combined together into a fused ring, and are each a substituent selected from the group consisting of a hydrogen atom, a halogen atom, a hydroxyl group, and substituted or unsubstituted alkyl, acyl, oxyalkyl, carboxyl, carboxylate ester, carboxamido, cyano, nitro, amino and aminoalkyl groups; and D1, D2 and D4 each represent a substituent, wherein at least one of D1, D2 and D4 is a substituent group comprising a vinyl group at an end thereof, and wherein the substituent group comprising a vinyl group at an end thereof enables the fluorescent monomer compound to be soluble in water, and (II) at least one hydrophilic, polymerizable monomer having a vinyl group.Type: GrantFiled: August 12, 2008Date of Patent: January 18, 2011Assignee: Terumo Kabushiki KaishaInventors: Shouji Ochiai, Tetsuro Kawanishi, Atsushi Matsumoto
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Patent number: 7871547Abstract: This invention provides a process for reducing the amount of soluble halide in a solution comprising a liquid organic medium, at least one viscosity reducing agent, at least one dihydrocarbylmagnesium compound, and an initial amount of soluble halide. The process comprises mixing at least one alkali metal with the solution at a mole ratio of alkali metal to magnesium of less than about 1:2.5, thereby forming precipitated soluble halides. Also provided by this invention is a process for reducing the amount of soluble halide in a slurry comprising a liquid organic medium, at least one viscosity reducing agent, at least one dihydrocarbylmagnesium compound, solids from the formation of said dihydrocarbylmagnesium compound, and an initial amount of soluble halide. This process comprises mixing at least one alkali metal with the slurry at a mole ratio of alkali metal to magnesium of less than about 1:1.25, thereby forming precipitated soluble halides.Type: GrantFiled: November 12, 2004Date of Patent: January 18, 2011Assignee: Albemarle CorporationInventors: Milind M. Pradhan, Chi Hung Cheng, Rajeev S. Mathur, Richard A. Holub, Donald W. Imhoff
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Patent number: 7872155Abstract: A method for deprotecting alkyl arylamine ethers to produce hydroxyl arylamine compounds by reacting the alkyl arylamine ether with a thiolate reagent. More specifically, a method for deprotecting alkyl arylamine ethers to produce hydroxyl arylamine compounds by reacting 2-(diethylamine)ethanethiolate with an alkyl arylamine ether to yield a hydroxy arylamine compound.Type: GrantFiled: November 15, 2007Date of Patent: January 18, 2011Assignee: Xerox CorporationInventors: Matthew A. Heuft, Jennifer A. Coggan, Nan-Xing Hu
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Patent number: 7868209Abstract: Provided is a new and improved process for preparing a borated alkaline earth metal toluene sulfonate salt.Type: GrantFiled: May 30, 2007Date of Patent: January 11, 2011Assignees: Chevron Oronite SA, Chevron Oronite Company LLCInventors: Perla Duchesne, John McDonald, Gilles Sinquin, Pierre Tequi
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Patent number: 7862984Abstract: A radiation-sensitive composition includes a free-radically polymerizable component, an initiator composition capable of generating free radicals sufficient to initiate polymerization upon exposure to imaging radiation, an infrared radiation absorbing compound, and a polymeric binder. The initiator composition includes a unique polyonium borate comprising a polyvalent onium cation with multiple onium moieties and sufficient organic borate counterions to provide a net neutral charge. The radiation-sensitive composition can be used to prepare a negative-working imageable element that is sensitive to suitable imaging infrared radiation, can be imaged at relatively low energy, and can be developed either on-press or off-press.Type: GrantFiled: March 28, 2007Date of Patent: January 4, 2011Assignee: Eastman Kodak CompanyInventors: Koji Hayashi, Jianbing Huang
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Patent number: 7863396Abstract: The present invention provides a silicon compound represented by Formula (1) and a polymer obtained by using the same, and this makes it possible not only to obtain an organic-inorganic composite material having a distinct structure but also to control the structure of the above polymer as a molecular aggregate. wherein R1 is a group independently selected from hydrogen, alkyl having a carbon atom number of 1 to 40, substituted or non-substituted aryl and substituted or non-substituted arylalkyl; in this alkyl having a carbon atom number of 1 to 40, optional hydrogens may be substituted with fluorine, and optional —CH2— may be substituted with —O—, —CH?CH—, cycloalkylene or cycloalkenylene; in alkylene in this arylalkyl, optional hydrogens may be substituted with fluorine, and optional —CH2— may be substituted with —O— or —CH?CH—; and A1 is a group having an ?-haloester group.Type: GrantFiled: March 5, 2004Date of Patent: January 4, 2011Assignee: Chisso CorporationInventors: Mikio Yamahiro, Hisao Oikawa, Kenya Ito, Yasuhiro Yamamoto, Masami Tanaka, Nobumasa Ootake, Kenichi Watanabe, Kohji Ohno, Yoshinobu Tsujii, Takeshi Fukuda
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Patent number: 7863476Abstract: This invention describes a composition of matter of the following structure: where m+n=1-30 or more, x+y=0-28, EO=oxirane PO=methyl oxirane M=H, Na, K, NH3, Amine, Ca, Mg, R and R1 are each separately and independently H, branched or linear alkyl, branched or linear alkenyl, A=aromatic, and, a+b=0 to 30.Type: GrantFiled: November 23, 2009Date of Patent: January 4, 2011Assignee: Oil Chem TechnologiesInventors: Paul Daniel Berger, Christie Huimin Berger
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Patent number: 7863482Abstract: A method for reducing the cyanide levels in a mesotrione sample, said method comprising: (i) taking an aqueous solution of the mesotrione sample in an aqueous solvent, (ii) adjusting the pH of said aqueous solution to a value of 9.5 or higher, and (iii) crystallising the mesotrione out of solution is disclosed.Type: GrantFiled: March 3, 2005Date of Patent: January 4, 2011Assignee: Syngenta Crop Protection, Inc.Inventors: Alan Henry Benke, Julie Marie Wichert