Abstract: An injection device and method are shown. Devices and methods include a forceps and a needle advancement mechanism to clamp a portion of tissue and control a depth of penetration of the needle between gripping ends of the forceps. An injection device and method are shown where selected components of the injection device such as a syringe and forceps are disposable, while the remaining portions of the injection device are reusable. Devices and methods are shown that utilize micro-needles to control a depth of penetration.

Abstract: A device which regulates the flow of a medical liquid includes a first and a second body, the first body featuring a first passage fluidly connected to a regulation channel, the second body featuring a second passage which may be positioned at a desired point of the regulation channel and set, during use, in fluid passage communication with the first passage by means of the regulation channel. The device includes a limiter which, once engaged, can no longer be disengaged during normal use of the regulation device, the first body or the second body featuring at least a first stop, and the limiter, when engaged, encountering the first stop in order to prevent the second passage being positioned in a predetermined portion of the regulation channel and/or at the first passage.

Abstract: A blinding cap for covering a needle shield that is covering a needle of a syringe includes an elongated body extending between a proximal end and an opposing distal end, the body at least partially bounding a chamber. An annular sleeve projects from the proximal end of the body and at least partially bounds a channel. A first flange radially inwardly projects from the body into the chamber, the first flange at least partially bounding an opening that provides communication between the chamber and the channel.

Abstract: One or more embodiments of the disclosure relate, generally, to a system to assist with manual dosing of insulin. Such a system may include a glucose sensor system, a reusable insulin dosing detector, and a recommendation system. The reusable insulin dosing detector may be configured to be reversibly connectable to a disposable component that may form part of an insulin manual delivery assembly. The reusable insulin dosing detector may be configured to detect insulin delivery associated with the insulin manual delivery assembly. The recommendation system may be configured to analyze blood glucose data and determine adjustments to insulin therapy settings.

Abstract: MVO is treated by introducing injectate into blood vessels affected by MVO at precise flow rates, while blocking retrograde flow, such that the natural pumping of the heart aids in forcing the injectate into the affected microvessels. Monitoring pressure distal of an occlusion balloon is used to determine treatment effectiveness and heart health.

Abstract: A syringe stabilizing apparatus has a base and a syringe support. The syringe support is vertically disposed above the base, elevating a fluid-filled portion of an infusion set vertically above the base and orienting a delivery end of the fluid-filled portion upwardly relative to a horizontal plane to take advantage of a gravitational effect on a fluid during delivery of the fluid from the fluid-filled portion to a patient. The syringe support comprises a first retainer and a selectively actuated tube clamp. The first retainer has an opening in which a rigid portion of the infusion set is received and retained therein without further user intervention. The selectively actuated tube clamp is operatively aligned with the first retainer. A flexible tube extending from the rigid portion of the infusion set extends through the selectively actuated tube clamp.

Abstract: A deflectable catheter shaft with compression resistance coils configured to create different curve shapes when the catheter is steered or deflected in different directions. One or more compression resistance coils may include an elongated-pitch section. The compression resistance coils may be pull wire compression coils or body compression coils.

Abstract: Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.

Abstract: An apparatus (1) for CRRT is provided comprising a blood circuit (10, 20, 30, 60) with a blood removal line (20), a treatment unit (10), and a blood return line (30). A replacement fluid container (78) is configured for containing a medical fluid, a pre-infusion line (70) has a first end (70-1) connected to the replacement fluid container (78) and a second end (70-2) connected to the blood removal line (20) and a blood pump (22) is active on the blood circuit. A replacement fluid pump (72) is active on the pre-infusion line (70), a dialysate circuit (40, 50, 70) comprises an effluent line (50) configured for discharging fluid from the second chamber, and a control unit (80) is connected to the replacement fluid pump (72) and to the blood pump (22) and is configured for performing a rinse-back procedure for restituting blood to a patient.

Abstract: A method of performing a rhizotomy includes directing an electrocautery probe through an incision in the body of a patient, navigating a distal tip of the probe to a location adjacent a target nerve, energizing the probe to deliver energy to the target nerve, and moving the distal tip of the probe in a plurality of directions to direct the energy at the target nerve.

Abstract: A laparoscopic suction/irrigation device of the disclosed invention encases a rigid inner cannula with a flexible outer cannula, the outer cannula functioning to insulate the inner cannula from unwanted electrical discharges. Upon translating the distal end of the outer cannula beyond the distal end of the inner cannula, the outer cannula returns to a preexisting curvilinear shape. This curved extension can thereafter be positioned via a proximal handle to concavities within the surgical site for precise and effective fluid retraction.

Abstract: The present invention provides an implantable microneedle and a manufacturing method therefor. An implantable microneedle according to the present invention comprises a coating layer for covering at least one part of the surface of a tip part of the microneedle. When exposed to moisture, the coating layer can be separated from the tip part of the microneedle and thus be implanted.

Abstract: Methods for treating fluid overload in a subject comprise shifting fluids directly and non-invasively from an interstitial compartment of the subject to skin of the subject through controlled local sweating. Methods of the invention allow for removal of excess fluid from the interstitial compartment of the subject and treat fluid overload in the subject. Sweat stimulation systems comprise a chamber and first and second relative humidity sensors. The chamber is sized to fit around a body part of a subject, comprises an inlet and an outlet, and is configured such that air flows through the chamber from the inlet to the outlet. The first relative humidity sensor is operably located inside the inlet, and the second relative humidity sensor is operably located proximate the outlet.

Abstract: One or more embodiments of the disclosure relate, generally, to a diabetes management system. The diabetes management system may include a computing device that is configured to receive data relating to prior insulin use of a user and calculate a sliding scale glucose correction based, at least in part, on the data relating to prior insulin use.

Abstract: A kit is disclosed for accurately loading a small volume dose of a medication within a syringe and for delivering the small volume dose of the medication at a treatment site. The kit generally includes a loading and delivery system in accordance herewith, a syringe, and a medication. The loading and delivery system includes a syringe delivery ring and a syringe loading guide, which may be used for example, to administer a small volume dose of a medication at the end of an ocular surgery.

Abstract: A catheter assembly including one or more conductive pathways to assist with placement of the catheter assembly into a patient's vasculature by enabling ECG signals emanating from the patient's heart to be detected, and a method for reconfirming an initial position of a distal end of a catheter tube of the catheter assembly. The conductive pathways can be configured to reconfirm via ECG signal detection proper placement of the catheter tube at a time subsequent to initial catheter placement into the vasculature. The catheter assembly can include an outer conductive pathway deposited on an outer surface of the catheter tube. The outer conductive pathway can have a distal end located distal to a portion of the catheter tube at a skin insertion site when the catheter tube is inserted into a patient.

Abstract: In some implementations, a PDT delivery device is disclosed that may include a housing including a handle, a fiber lock orifice, a probe insertion orifice and a tube retraction groove positioned between the fiber lock orifice and the probe insertion orifice. In addition, the PDT delivery device may include an insertion probe having a stepped hollow cylinder positioned within the probe insertion orifice and within the tube retraction groove and having an insertion needle at a distal end. The PDT delivery device may include a fiber locking mechanism and a probe release mechanism selectively movable between an unlock position and a lock position. Also, the PDT delivery device may include a probe retraction mechanism releasably coupled to the insertion probe. Further, the PDT delivery device may include a retraction trigger coupled to the probe retraction mechanism to translate the insertion probe between an insertion position and a retraction position.

Abstract: The invention encompasses improved catheters comprised of multiple tubular bodies and methods of using them in artificial insemination.

Abstract: A fluid sampling or infusion device for an extracorporeal blood treatment apparatus comprises: a protective body (29) having a first aperture (30) and a second aperture (31) and comprising a connecting device (28) configured to connect, optionally in removable manner, the protective body (29) to a sampling or infusion site (20) of the extracorporeal blood treatment apparatus (1); a needle assembly (33) comprising a first end (34) connected or connectable, optionally in removable manner, to a syringe (22) and a needle (35) protruding from a second end opposite the first end (34). The needle assembly (33) is movable inside the protective body (29) between a first position and a second position. In the first position the needle (35) is completely enclosed by the protective body (29) and in the second position the needle (35) protrudes from the second aperture (31) to pierce the sampling or infusion site (20).

Abstract: Systems and methods are disclosed that include a guide catheter apparatus insertable through an external body passage of a subject. The guide catheter apparatus includes a substantially rigid shaft and a handle. The shaft has a proximal opening, a distal opening, and a lumen extending between the proximal opening and the distal opening. The handle has a structure to allow a position of the guide catheter to be controlled by some or all of three fingers of one hand of an operator of the handle. The structure of the handle is adapted to permit the operator to position a thumb and index finger of the hand to manipulate a working device inserted into the lumen of the guide catheter, where the working device is manipulable via a portion of the working device immediately adjacent to the handle.