Abstract: Novel peptide analogs derived from the native sequences of CAP37 peptides 20-44 and 23-42, and their use as therapeutics against bacterial infections and diseases caused by bacterial infection. The peptide analog includes a serine or threonine substitution at one of the two cysteine residues at positions 26 and 42. Substitutions of the native peptide are also contemplated.
Type:
Grant
Filed:
March 1, 1999
Date of Patent:
August 22, 2000
Assignee:
The Board of Regents of the University of Oklahoma