Abstract: A method for detecting deposited particles (P) on a surface (11) of an object (3, 14) includes: irradiating a partial region of the surface (11) of the object (3, 14) with measurement radiation; detecting measurement radiation scattered on the irradiated partial region, and detecting particles in the partial region of the surface of the object (3, 14) based on the detected measurement radiation. In the steps of irradiating and detecting, the surface (11) of the object (3, 14) has an anti-reflective coating (13) and/or a surface structure (15) for reducing the reflectivity of the surface (11) for the measurement radiation (9), wherein the particle detection limit is lowered due to the anti-reflective coating (13) and/or the surface structure (15). Also disclosed are a wafer (3) and a mask blank for carrying out the method.

Abstract: Systems for confocal Raman spectroscopy of points of interest or regions of interest with concurrent imaging are disclosed. The imaging may be used for real time selection of points of interest or regions of interest for Raman spectroscopy and to monitor for unwanted motions of a sample while Raman spectra are acquired. Disclosed embodiments apply Reflectance confocal microscopy (RCM) in a confocal Raman spectroscopy system. A single laser may be used as a light source for both RCM and micro-Raman spectroscopy. A Faraday optical isolator may be applied to extract RCM signals for imaging Systems as described herein have example application for ex vivo sample and in vivo skin measurement.

Abstract: The invention relates to a method and device for simultaneously measuring mass concentrations of particulates with different sizes. The method detects particulates within different size ranges in air based on laser scattering and can eliminate cross interference between the particulates within different size ranges. The device is simple in structure, can realize on-line simultaneous measurement of PM1.0, PM2.5 and PM10 with high measurement precision and low cost.

Abstract: A computer-implemented method of automatically generating inspection templates of a plurality of known good fasteners to identify fasteners at an inspection station is provided. The method includes providing a data entry mechanism to provide content needed to identify a plurality of unidentified mixed fasteners. The method also includes storing the content in a database, extracting the content from the database and creating the inspection templates from the extracted content. Each of the templates including a fastener profile and a set of features. Each of the features includes a range of acceptable values. Each of the templates has a fastener identification code associated therewith.

Abstract: A particulate matter sensor system for sensing particulate matter in a fluid includes a substrate and a cover disposed on the substrate. The cover defines at least a portion of a flow path through the microfluidic system. The sensor system includes a particulate matter sensor disposed in an interior space between the cover and the substrate. The particulate matter sensor includes an integrated sensor device electrically connected to the substrate. The flow path is defined through the particulate matter sensor. The sensor system includes a fluid circulation device disposed in the interior space between the cover and the substrate and configured to cause fluid to flow along the flow path through the microfluidic system.

Abstract: A ternary fluorescence correlation spectroscopy system for analyzing an interaction between three kinds of molecules, including at least three excitation light sources with different wavelengths. The excitation light sources are configured to illuminate and excite a sample to generate a fluorescence signal. The fluorescence signal is divided into multiple signals according to wavelength, which are then respectively detected by a single photon detector and transmitted to a signal acquisition and operation card to perform real-time operation of a triple-correlation function, so as to obtain a fluorescence triple-correlation spectroscopy curve.

Abstract: An optical sensor device may include an optical sensor that includes a set of sensor elements; an optical filter that includes one or more channels; a phase mask configured to distribute a plurality of light beams associated with a subject in an encoded pattern on an input surface of the optical filter; and one or more processors. The one or more processors may be configured to obtain, from the optical sensor, sensor data associated with the subject and may determine a distance of the subject from the optical sensor device. The one or more processors may select, based on the distance, a processing technique to process the sensor data, wherein the processing technique is an imaging processing technique or a spectroscopic processing technique. The one or more processors may process, using the selected processing technique, the sensor data to generate output data and may provide the output data.

Abstract: Provided is a measurement device including a spectroscope, a movement mechanism configured to relatively move the spectroscope along a first direction with respect to the measurement target, and one or more processors configured to execute detecting a measurement error indicating that spectroscopic measurement processing by the spectroscope is not executed normally, and controlling the spectroscope and the movement mechanism, in which the one or more processors, when the measurement target is a plurality of color patches arranged along the first direction, cause the spectroscope to execute first measurement processing of measuring light with a specific wavelength set in advance while relatively moving the spectroscope in the first direction to acquire a measured value with respect to the specific wavelength obtained by the first measurement processing and a position of the spectroscope, and when the measurement error is detected, move the spectroscope to a position where an amount of variation of the measured

Abstract: The present invention discloses an aspheric lens eccentricity detecting device based on wavefront technology and a detecting method thereof. The device comprises: an upper optical fiber light source, an upper collimating objective lens, an upper light source spectroscope, an upper beam-contracting front lens, an upper beam-contracting rear lens, an upper imaging detector, an upper imaging spectroscope, an upper wavefront sensor, a lens-under-detection clamping mechanism, a lower light source spectroscope, a lower beam-contracting front lens, a lower beam-contracting rear lens, a lower imaging spectroscope, a lower wavefront sensor, a lower imaging detector, a lower collimating objective lens and a lower optical fiber light source.

Abstract: An automatic analysis apparatus comprises: a light source generating light having a center wavelength equal to or shorter than 340 nm; a fluorescent substance excited by the light source light, and generates light together with transmitted light from the light source, having a wavelength of 340 nm to 800 nm; a condenser lens; at least one slit; a reaction cell holding a reaction solution where a specimen and reagent are mixed, and that the light source light and the light from the fluorescent substance enter; and a detector that detects light transmitted through the reaction cell. The light source, fluorescent substance, condenser lens, and slit are provided along a straight light corresponding to the optical axis. The width of the slit's opening is equal to or narrower than the width of a ray forming an image of the light source at the position of the slit.

Abstract: A device for monitoring a bioreactor is configured for in-situ analysis, e.g., by NIR, without the need for withdrawing a sample into a sample cell or into an ex-situ arrangement. The device can be inserted into a port of the bioreactor and provides a sample detection region defined by an optical element such as a lens and a photodetector. The electrical signal obtained from a photodetector that is part of the device can be directed to an analyzer via a detachable electrical connection.

Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).

Abstract: Various embodiments of the present invention relate to an apparatus and method for measuring the surface of an electronic device, the apparatus comprising: a seating portion on which the electronic device is seated; a first light source for irradiating first light on the surface of the electronic device; a first camera for photographing the surface using the first light; a second light source for irradiating second light on the surface of the electronic device; a second camera for photographing the surface using the second light; and an analyzer electronically connected to the first light source, the first camera, the second light source, and the second camera, wherein the analyzer is setup to analyze the color of the surface acquired using the first light source and the first camera; and the gloss of the surface acquired using the second light source and the second camera, so as to analyze the color and gloss of the surface of the electronic device using quantified and digitized data, thereby enabling qualit

Abstract: In order to make it possible to conduct a zero calibration even though an interference gas exists in a measurement area of a detector, a light absorbance analysis apparatus includes a detector that detects an intensity of light that transmits a gas, a total pressure sensor that measures a total pressure of the gas, an absorbance calculating part that calculates an absorbance based on an output value of the detector and a previously set zero reference value, a partial pressure—absorbance relation storing part that stores a partial pressure—absorbance relational data that indicates a relationship between a partial pressure of an interference gas that exists in a measurement area of the detector and an absorbance calculated by the absorbance calculating part, and a partial pressure calculating part that calculates an interference gas partial pressure as a partial pressure of the interference gas.

Abstract: This application described methods and apparatus for distributed fibre optic sensing. A sensing apparatus has a modulator which modulates radiation from an optical source to interrogate a sensing optical fibre with a first interrogation pulse at a first frequency (F1) and a second interrogation pulse at a second, different, frequency (F2), both different in frequency from a local oscillator (LO). A mixer mixes backscatter from the sensing optical fibre with the local oscillator and supplies the mixed signal to a detector that provides a corresponding digital signal. A processor processes the digital signal (DX, DY) in a first and second processing channels to demodulate respective first and second phase signals based on the respective frequency difference between the first and second frequency and the local oscillator and determines a temporal difference between the first and second phase signals.

Abstract: The present invention relates to a fluorescence sensor for measuring microalgae and a method of operating the same. The fluorescence sensor for measuring the microalgae includes a fluorescence measurement unit including a light emitter configured to irradiate excitation light onto a measurement region and a detector configured to measure fluorescence emitted from the measurement region, an algae control unit configured to form a node and an antinode of an ultrasonic standing wave in the measurement region to control an algal density, and a signal processing unit configured to calculate the algal density using fluorescence intensity signals according to an operation mode of the algae control unit.

Abstract: A method performed by a multispectral or hyperspectral meibomian gland imaging device is disclosed, which comprises directing light having visible and infrared spectra from a broadband illuminator toward an everted eyelid; forming images of the everted eyelid using an imaging system; recording the images using a detection system, which separates the images into spectral channels, which include at least one visible spectral channel and at least one infrared spectral channel; displaying the recorded images to adjust the position of the subject to optimize image quality; digitally processing the recorded images to obtain spatial and spectral information; evaluating the health of at least one meibomian gland of the eyelid by analyzing the information. Also disclosed is a multispectral or hyperspectral meibomian gland imaging device, comprising a broadband illuminator directing light that covers visible and infrared spectra; an imaging system, and a detection system.

Abstract: An optical coherence tomographic device may include: a light source; a measurement light generator that generates measurement light and generates reflected light from a target region in a scattering sample by irradiating the target region with the measurement light; a reference light generator that generates reference light; an interference light generator that generates interference light by combining the reflected light and the reference light; an interference light detector that detects the interference light and generates interference signals by converting the interference light; and a processor. The processor may cause the OCT device to execute: acquiring tomographic images for a same cross section in the target region in time series from the interference signals; calculating an entropy of the generated interference signals based on the tomographic images; and specifying a dynamic part in the tomographic images based on the calculated entropy.

Abstract: A particle sizing system is provided that includes an optical source generating a light beam for illuminating particles in a monitored volume, a plurality of light deflectors, each positioned to receive and deflect light scattered by the particles, and an image capture device collecting scattered light deflected by each light deflector. The image capture device outputs an image including a plurality of sub-images, each generated from the collected light deflected from a respective one of the light deflectors. Each particle is imaged as a spot in each sub-image, the plurality of spots associated with each particle corresponding to a plurality of scattering angles. The system also includes a processing unit configured to identify the spots associated with each particle in the sub-images, compute a spot parameter associated with each spot, and determine the size of each particle from its related spot parameters. A particle sizing method is also provided.

Abstract: A biosensing device for continuous monitoring of an analyte in a fluid matrix includes an electromagnetic excitation element [402], a biosensing surface [406], an opposing surface [410], a separation component [420,422], light collection optics [412], a light sensor [414], an image recording and analysis system [416], and an excitation control system [400]. The separation component is connected to the biosensing surface and to the opposing surface, forming a concave gap region [408] between the biosensing surface and the opposing surface. The biosensing surface comprises biosensing particles sensitive to electromagnetic signals from the electromagnetic excitation element, where an optical response of the biosensing particles to the electromagnetic signals is adapted to change in the presence of an analyte in the gap region. The light collection optics couple light emitted from the biosensing particles on the biosensing surface to the light sensor.