Abstract: The present invention provides for a release system for delaying application of chemical reagents in a lateral-flow immunoassay. A chemistry release fiber comprising a permeable membrane and a chemical release agent is used to delay chemical reagent delivery to the indicator of a lateral-flow immunoassay. Also disclosed is the related method of delaying application of chemical reagents in a lateral-flow immunoassay.

Abstract: The present disclosure provides a sensor substrate in which deterioration of a first specific-binding substance immobilized on a surface of the sensor substrate is suppressed even when the sensor substrate is washed or dried. The present sensor substrate includes a base material; a first specific-binding substance having a property of binding specifically to an analyte, the first specific-binding substance being immobilized on a surface of the base material; and a first sugar molecule. The first sugar molecule is immobilized on the surface of the base material by a chemical bond.

Abstract: The present invention relates to methods of detecting CD200L in a female subject from a secretory phase biological sample. Increased levels of CD200L have been determined to be associated with endometriosis. CD200L is therefore a useful biomarker for the diagnosis of endometriosis and a useful target for therapeutic intervention.

Abstract: A time-resolved fluorescence immunochromatographic test paper card for testing clothianidin. A binding pad includes a detection microsphere and a quality control microsphere thereon, wherein the detection microsphere is a fluorescent microsphere coated with a clothianidin monoclonal antibody on the surface thereof, the quality control microsphere is a fluorescent microsphere coated with a rabbit anti-tag protein on the surface thereof. An NC film is provided with a detection line and a control line. The lengths of the detection line and the control line are the same as the width of the NC film. A first clamping part is arranged at one end of the sample pad. A second clamping part and a third clamping part are respectively arranged at two ends of the binding pad. A fourth clamping part is arranged at one end of the NC film, the other end of the NC film is joined with an absorption pad.

Abstract: A time-resolved fluorescence immunochromatography test paper card for detecting butralin, which comprises a cover body and a housing body, wherein the cover body is provided with a test hole, a loading hole and a through-hole, an isolating mechanism is arranged in the test hole and the loading hole, the isolating mechanism comprises a first isolating ring and a second isolating ring, the top lateral walls of which are respectively provided with a first lug boss and a second lug boss, one end of the upper surface of the working board is concave towards the inner of the working board to provide a groove, there is a nitrocellulose membrane, a binding pad, a sample pad and a mark zone successively provided between the water absorbing block and the other end of the working board, and the lateral wall at one end of the working board is provided with a bump.