Abstract: A conductive transfer for application to an article comprises first and second non-conductive layers and a conductive layer positioned between the two non-conductive layers. The conductive transfer further comprises an adhesive layer for adhering the conductive transfer to an article, such as a wearable item. The conductive layer comprises a plurality of tessellated cells defined by a printed conductive ink. The conductive layer comprises a main element and an input track with the plurality of tessellated cells being comprised over the input track of said conductive layer.

Abstract: The device comprises: a laser source (7); a treatment hand-piece (13); a light guide (11) configured to convey a laser beam from the laser source to the hand-piece. The hand-piece (13) is configured to vary the inclination of the laser beam (F2) exiting from the hand-piece with respect to a longitudinal axis (A-A) of the hand-piece.

Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells and treating a subject's kidneys.

Abstract: An example of a system for monitoring and treating a medical condition of a patient may include signal inputs to receive patient condition signals indicative of a state of inflammatory bowel disease (IBD), a signal processing circuit configured to process the patient condition signals and generate patient condition parameters indicative of the state of IBD using the processed patient condition signals, and a medical condition analyzer configured to analyze the patient condition parameters and determine the medical condition including the state of IBD using an outcome of the analysis. The patient condition parameters may include one or more physiological marker parameters each representative of a physiological marker of IBD and one or more quality of life parameters each being measure of quality of life of the patient.

Abstract: In some examples, a battery assembly for an implantable medical device. The battery assembly may include an electrode stack comprising a plurality of electrode plates, wherein the plurality of electrode plates comprises a first electrode plate including a first tab extending from the first electrode plate and a second electrode plate including a second tab extending from the second electrode plate; a spacer between the first tab and the second tab; and a rivet extending through the first tab, second tab, and spacer, wherein the rivet is configured to mechanically attach the first tab, second tab, and spacer to each other.

Abstract: Pocket-size folding device with integrated electrodes for recording, processing and transmission with three ECG leads is a hand held ECG device with integrated electrodes used to measure, process and transmit three ECG leads to the remote diagnostic center. When in closed position and not in use the device is more compact and robust so it can be carried in a pocket or a pouch while electrodes are protected from getting dirty or damaged When opening it into a measuring position it becomes ergonomic. It is well adapted to the shape of a user's chest which ensures stable and reliable contact between chest electrodes (4-6) and chest surface. Finger electrodes (7,8) are designed for a contact with left hand and right hand thumbs as well as supporting the device and ensuring sufficient pressure to the chest without intense use of user's arms. The device is compact, it doesn't use cables or levers which makes it very easy to use.

Abstract: An implant includes a housing that houses circuitry that is electrically coupled to one or more electrodes. The implant includes an antenna that is electrically coupled to the circuitry. The antenna has a pre-treatment state in which the antenna is not shaped to receive wireless power for treating a subject, and a treatment state in which the antenna is shaped to receive wireless power and to anchor the implant with respect to a nerve of the subject. Other embodiments are also described.

Abstract: An extravascular or intravascular neural interface is disclosed containing electrodes for neurostimulation of the vessel. The devices are housed in flexible substrates formed from a multilumen tubing housing conductors for electrodes positioned in a distal serpentine shaped end of the device. The distal serpentine shaped end includes rows or strips of electrodes or coil electrodes.

Abstract: A lead anchor comprising a longitudinally extending anchor body and a retainer. The longitudinally extending anchor body having a lumen positioned to receive a spinal cord lead therethrough and having a retainer pocket intersecting the lumen. The retainer is positioned in the retainer pocket. The retainer comprises a first grip member having at least one first aperture, a second grip member having at least one second aperture, and at least one U-shaped resilient portion connecting the first and second grip members.

Abstract: A pacemaker fixation system, a leadless pacemaker system and a method of use thereof are disclosed. The leadless pacemaker system includes: a pacemaker fixation system including a leadless pacemaker and an elastic unfoldable element attached thereto, wherein in an unfolded configuration of the elastic unfoldable element, it fixes the leadless pacemaker at a target location in a blood vessel in communication with the heart; a delivery system for delivering the pacemaker fixation system to the target location; and a guide for guiding the delivery system into the blood vessel. According to the present invention, atrial pacing can be achieved by the leadless pacemaker through fixing the leadless pacemaker in the blood vessel in communication with the heart with the elastic unfoldable element.

Abstract: A surgical instrument is disclosed comprising an actuator and circuitry mounted on and/or embedded in the actuator.

Abstract: Systems and methods for positioning implanted devices in a patient are disclosed. A method in accordance with a particular embodiment includes, for each of a plurality of patients, receiving a target location from which to deliver a modulation signal to the patient's spinal cord. The method further includes implanting a signal delivery device within a vertebral foramen of each patient, and positioning an electrical contact carried by the signal delivery device to be within ±5 mm. of the target location, without the use of fluoroscopy. The method can still further include, for each of the plurality of patients, activating the electrical contact to modulate neural activity at the spinal cord. In further particular embodiments, RF signals, ultrasound, magnetic fields, and/or other techniques are used to locate the signal delivery device.

Abstract: A drive transfer element for transferring drive between a surgical robot arm and a surgical instrument, the drive transfer element comprising a drive transfer element recess being releasably engageable with an interface protrusion; and a drive transfer element protrusion being releasably engageable with an interface recess; the drive transfer element protrusion comprising a cavity in communication with the drive transfer element recess so as to enable the interface protrusion engageable with the drive transfer element recess to project into the cavity.

Abstract: Systems and methods for managing cardiac arrhythmias are discussed. A data management system receives a first detection algorithm including a detection criterion for detecting a cardiac arrhythmia. An arrhythmia detector detects arrhythmia episodes from a physiologic signal using a second detection algorithm that is different from and has a higher sensitivity for detecting the cardiac arrhythmia than the first detection algorithm. The arrhythmia detector assigns a detection indicator to each of the detected arrhythmia episodes. The detection indicator indicates a likelihood that the detected arrhythmia episode satisfies the detection criterion of the first detection algorithm. The system prioritizes the detected arrhythmia episodes according to the assigned detection indicators, and outputs the arrhythmia episodes to a user or a process according to the episode prioritization.

Abstract: An apparatus comprises a magnetic field detection circuit, a cardiac signal sensing circuit, a memory circuit, a control circuit, and an arrhythmia detection circuit. The cardiac signal sensing circuit generates a cardiac signal representative of cardiac activity of a subject when coupled to sensing electrodes. The control circuit is operatively coupled to the magnetic field detection circuit; the cardiac signal sensing circuit, and the memory circuit. The control circuit stores cardiac signal data determined using the sensed cardiac signal, receives an indication of magnetic field detection by the magnetic field detection circuit, stores data obtained using the sensed cardiac signal during the magnetic field detection, and stores an identifier indicating the magnetic field detection in association with the data. The arrhythmia detection circuit processes the cardiac signal data to detect a cardiac arrhythmia event and confirm the cardiac arrhythmia event according to the magnetic field indication.

Abstract: An implantable medical device includes a header body and a septum assembly. The header body includes a first welding surface and a septum bore extending inwardly from an outer surface to an inner cavity. The septum assembly is at least partially disposed within the septum bore of the header assembly and includes a septum configured to allow insertion of a tool through the septum into the inner cavity and to otherwise provide a seal. The septum assembly further includes a retainer within which at least a portion of the septum is retained. The retainer includes a welding feature coupled to the retainer body, the welding feature providing a second welding surface. The retainer is coupled to the header body by welding the first welding surface to the second welding surface.

Abstract: Medical devices include a separate enclosure that houses a battery and electrically isolates the battery from external conditions such as any metal enclosures and ultimately isolates the battery from body fluids. Thus, the separate enclosure attaches to a housing of a medical device and provides for modularity of the battery which allows, for instance, different size batteries to be used with the same medical device design. The separate enclosure further prevents stimulation current from leaking back to the battery housing by providing the electrical isolation.

Abstract: A device for relieving pains and spasms by applying electrical pulses which makes it possible to render the electrical pulses easier to tolerate by limiting or preventing the painful or untimely discharges which hamper the use of the relief device. The relief device delivers electrical pulses only when it bears or rolls in a back-and-forth movement on the skin or clothing of a user. The relief device comprises means for limiting the maximum voltage delivered to the user, one or more means of triggering the pulses delivered by the electrodes, an activation delayer and a system for progressively launching the potential delivered by the electrodes.

Abstract: Described is a system for automatic adjustment of neurostimulation. The system controls stimulation of specific neural regions through a neural device positioned on a human subject, while simultaneously performing recordings from the neural device using a targeted arrangement of stimulating electrodes and distinct types of recording electrodes of the neural device. Stimulation of the specific neural regions is adjusted in real-time based on the recordings from the neural device.

Abstract: The systems and methods described herein include an external base station with a tethered transceiver, an implanted hub that includes power, telemetry, and processing electronics, and a plurality of implanted satellite that contain reconfigurable front-end electronics for interfacing with electrodes. The system can operate in different modes. In a first mode, called a base boost mode, the external base station is used for closed-loop control of stimulation therapies. In a second, autonomous mode, closed-loop control is performed in the hub without direct influence from the base station. In a third mode, streams of neural data are transmitted to an offline processor for offline analysis.