Abstract: Systems, devices, and methods are presented for automatic tuning, calibration, and verification of radiation therapy systems comprising control elements configured to control parameters of the radiation therapy systems based on images obtained using electronic portal imaging devices (EPIDs) included in the radiation therapy system.

Abstract: Aspects of the present disclosure describe techniques for independently controlling an angle (e.g., change in tilt) and/or position (e.g., change in lateral position) of an optical beam. For example, an optical beam control system may include a telescope with rotatable mirrors and lenses configured to provide a path to an optical beam to produce an output optical beam, which in turn is made into parallel optical beams following a diffractive optical element. The optical beam control system may also include a detector system to a beam angle and/or a beam position of one of the parallel optical beams to generate feedback signal or signals to control a rotation of one or more of the mirrors in the telescope such as to adjust the beam angle, the beam position, or both of the parallel optical beams. The optical beam control system may be part of a quantum information processing (QIP) system.

Abstract: A detector system for an x-ray imaging device includes a detector chassis, a plurality of sub-assemblies mounted to the detector chassis and within an interior housing of the chassis, the sub-assemblies defining a detector surface, where each sub-assembly includes a thermally-conductive support mounted to the detector chassis, a detector module having an array of x-ray sensitive detector elements mounted to a first surface of the support, an electronics board mounted to a second surface of the support opposite the first surface, at least one electrical connector that connects the detector module to the electronics board, where the electronics board provides power to the detector module and receives digital x-ray image data from the detector module via the at least one electrical connector. Further embodiments include x-ray imaging systems, external beam radiation treatment systems having an integrated x-ray imaging system, and methods therefor.

Abstract: A radiation detection system may include a mobile device having a flash memory. The device may monitor various characteristics of the flash memory to determine when damage to the flash memory has occurred from radiation exposure. The device may associate damage to the flash memory with a radiation dose, and determine a level of radiation to which the memory, and thus the device, has been exposed. The device also may determine a length of time and locations where the radiation exposure has occurred. If the device determines that the level of radiation exposure exceeds a threshold associated with a safe level of radiation exposure for a human user, the device may generate an alert to the user.

Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.

Abstract: The present disclosure discloses a flat panel detector, a driving method thereof and a detection device. The flat panel detector includes: at least one stage of first demultiplexer, wherein signal output terminals of a first stage of first demultiplexer are connected with the scanning signal lines in one-to-one correspondence, signal output terminals of other stage of first demultiplexer serves as signal input terminals of the previous stage of first demultiplexer, the first demultiplexers are configured to provide signals of the signal input terminals to all the signal output terminals in time division, the signal input terminals and the signal output terminals included in the different stages of first demultiplexers differ from one another, and the quantity of the signal input terminals and the quantity of the signal output terminals are reduced stage by stage from the first stage of first demultiplexer to the last stage of first demultiplexer.

Abstract: The present invention relates to the dose adjustment device mountable to diagnostic radiation equipment and the dose adjustment system which allows radiation exposure in each portion of in the irradiation area to be prevented, and are configured as modules that are attachable to diagnostic radiation equipment, thus having the effect of allowing a radiation shielding function to be easily added to existing equipment without changing the structure thereof.

Abstract: An estimation device includes at least one processor, in which the processor functions as a learned neural network that derives a result of estimation of at least one emphasis image in which a specific composition of a subject including a plurality of compositions is emphasized from a simple two-dimensional image acquired by simply imaging the subject. The learned neural network is learned by using, as teacher data, a composite two-dimensional image representing the subject, which is derived by combining a three-dimensional CT image of the subject, and an emphasis image for learning in which the specific composition of the subject is emphasized, which is derived from the CT image.

Abstract: Disclosed herein are MEMS devices and systems and methods of manufacturing or operating the MEMS devices and systems. In some embodiments, the MEMS devices and systems are used in imaging applications.

Abstract: For decision support in a medical therapy, machine learning provides a machine-learned generator for generating a prediction of outcome for therapy personalized to a patient. Deep learning may result in features more predictive of outcome than handcrafted features. More comprehensive learning may be provided by using multi-task learning where one of the tasks (e.g., segmentation, non-image data, and/or feature extraction) is unsupervised and/or draws on a greater number of training samples than available for outcome prediction alone.

Abstract: There is provided a method for determining presence of a person comprising a) receiving IR sensor data (50) during a first time period from a thermopile and using the IR sensor data to determine an IR background signal baseline (51) for the time period, and determining a variability of the IR sensor data (50), b) using the IR background signal baseline (51) and the variability of the IR background signal level to determine a threshold (52) with a value higher than the background signal baseline (51), and in such a way so that greater variability in the IR background signal (50) results in a higher threshold (52), then c) receiving further IR sensor data (50) during a second time period, which is after the first time period, and using the further IR sensor data (50), and the threshold (52) determined in step b) to determine that a person is present when the further IR sensor data (50) comprises a value that is higher than the threshold.

Abstract: An apparatus for detecting X-ray, comprising an X-ray absorption layer comprising an electrode, an electronics layer and a wall sealing a space among electrical connections between the X-ray absorption layer and the electronics layer. The electronics layer comprises: a first and second voltage comparators configured to compare a voltage of an electrode to a first and second thresholds respectively; a counter configured to register a number of X-ray photons absorbed by the X-ray absorption layer; and a controller configured to: start a time delay from a time at which an absolute value of the voltage equals or exceeds an absolute value of the first threshold; activate the second voltage comparator during the time delay; cause the number registered by the counter to increase by one, if, during the time delay, an absolute value of the voltage equals or exceeds an absolute value of the second threshold.

Abstract: A radioactivity measurement device for measuring an activity level of a radioisotope source is provided. The radioactivity measurement device comprises a housing and a self-powered detector. The housing comprises an outer shell and an inner shell, wherein the inner shell is adapted to house an insertable radioisotope source, and wherein the outer shell and the inner shell are configured to form a hollow annular region. The self-powered detector, positioned within the hollow annular region of the housing, comprises at least one tubular emitter configured to provide a source of electron emission proportional to a radioisotope activity level of the insertable radioisotope source and at least one tubular collector configured to sink the electron emission. A radioactivity level measurement system comprising at least one radioactivity measurement device, a shipping cask incorporating the radioactivity level measurement system and a method for shipping the shipping cask are also provided.

Abstract: The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample. The method involves the use of fluorescence of naturally-occurring species in tissue to determine the location of the tissue in the embedded sample. An embedded sample is generally excited by light of a selected wavelength, and the fluorescence emission at an emitted wavelength is used to locate the boundary or location of the tissue in the embedded sample.

Abstract: The invention provides a detection system for ionizing radiation, a method of manufacturing a detection system for ionizing radiation, a method of detecting ionizing radiation, a detection chamber for detecting ionizing radiation by liquid scintillation counting, and a method of detecting ionizing radiation by liquid scintillation counting. The detection system for ionizing radiation comprises a detector with a detection surface. The detector is configured to detect ionizing radiation that is incident on the detection surface. An adsorption layer is provided on said detection surface, the adsorption layer being configured to bind target particles, wherein the target particles are radioactive atoms or molecules.

Abstract: Image information regarding a particular patient is provided, which image information includes, at least in part, a tumor to be irradiated. These teachings can also include providing non-image clinical information that corresponds to the particular patient. A control circuit accesses the foregoing image information and non-image clinical information and automatically generates a clinical target volume that is larger than the tumor as a function of both the image information and the non-image clinical information. The control circuit can then generate a corresponding radiation treatment plan based upon that clinical target volume, which plan can be utilized to irradiate the clinical target volume.

Abstract: Techniques are presented for optimizing a treatment plan for charged particle therapy. The method includes obtaining medical image data voxels inside a subject in a reference frame of a radiation source that emits a beam of charged particles at multiple tracks with a controlled emitted energy at each track. Hydrogen density (HD) is determined based on the medical image data. Stopping power ratio (SPR) along a first beam having a first track and first emitted energy is calculated based on HD. A range to a Bragg peak is calculated along the first beam based on the SPR and the first emitted energy. The first beam track or the first emitted energy, or both, is modified based at least in part on the beam range to determine a second track and second emitted energy. Output data that indicates the second track and second emitted energy are sent.

Abstract: A system for imaging particles in a fluid includes a substrate holder for holding a substrate comprising a channel or reservoir for containing the fluid in the substrate, a radiation source for providing irradiation in the substrate and a radiation detection unit for detecting particles in the fluid in the substrate. At least one of the radiation source and the radiation detection unit) are configured to obtain detection in one or more distinct detection sheets in the substrate. The system further comprises an actuator configured for imparting an oscillating mechanical movement of the substrate holder regarding the radiation detection unit and the radiation source, the oscillating mechanical movement being a movement comprising a movement component in a direction perpendicular to the plane wherein the one or more detection sheets are extending.

Abstract: An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.

Abstract: The treatment couch includes a couch panel, a main supporting structure, an auxiliary supporting structure and a supporting beam. Both ends of the supporting beam are respectively connected to the main supporting structure and the auxiliary supporting structure.