Abstract: A device and array coupled to capture molecules are provided. Specifically, the device and array can be used for detecting the presence and concentration of biomarkers in a sample from a subject. The device and array can also allow the use of a method for scoring a sample for, e.g., the purpose of diagnosing a disease. The method can also be advantageous to applications where there is a need to accurately determine the disease stage of a subject for the purpose of making therapeutic decisions.
Type:
Grant
Filed:
August 21, 2014
Date of Patent:
June 14, 2016
Assignee:
Lawrence Livermore National Security, LLC
Inventors:
Rupa S. Rao, Stephen M. Lane, Dennis L. Matthews, Matthew A. Coleman
Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
Type:
Grant
Filed:
December 20, 2011
Date of Patent:
December 9, 2014
Assignee:
Randox Laboratories Limited
Inventors:
Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
Abstract: A composition for use as an assay reagent comprises a solid support comprising a member of a signal producing system and a coating of a synthetic copolymer. The synthetic copolymer comprises a first polymerized monomer comprising a pendant moiety comprising a reactive functionality or a derivative of a reactive functionality and a second polymerized monomer comprising a pendant moiety comprising at least 1 carbon atoms and at least 2 heteroatoms. In some embodiments the copolymer comprises a polyethylenic backbone comprising the pendant moiety comprising a reactive functionality or a derivative of a reactive functionality and the pendant moiety comprising at least 1 carbon atom and at least 2 heteroatoms.
Type:
Grant
Filed:
April 9, 2012
Date of Patent:
October 1, 2013
Assignee:
Siemens Healthcare Diagnostics Inc
Inventors:
Bhalchandra Lele, Pratap Singh, Raphael Bartz, Jason A. Kellogg