Abstract: Neural network based heart rhythm classifiers are described. The neural network is configured to receive an electrocardiogram segment and to output an indication of whether the electrocardiogram segment represents a heart rhythm that is suitable for treatment by a defibrillation shock. Preferably, the received electrocardiogram segment is not transformed or processed prior to its reception by the neural network and no features of the electrocardiogram are identified to the neural network. In some embodiments, the received electrocardiogram segment is the sole input to the neural network. In various embodiments, the neural network is configured to classify electrocardiogram segments obtained while CPR was being performed on the patient. Classifiers that output a characteristic of CPR are also described. Such outputs may include an indication of whether CPR was being performed while the ECG was being detected, compression depth, etc. The described classifiers are well suited for use in defibrillators.

Abstract: A surgical system is disclosed. The surgical system includes a monopolar return pad and a surgical hub wirelessly coupled to the monopolar return pad. The surgical hub includes a control circuit configured to determined a presence and a position of a patient on the monopolar return pad according to data received from the monopolar return pad.

Abstract: Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients or to a set of rules developed from the database. An ST segment and one or more ST subwaveforms within the ST segment are identified from the plurality of subwaveforms and discontinuity points based on the comparison. The ECG waveform with the one or more ST subwaveforms within the ST segment is displayed.

Abstract: A method for aesthetic soft tissue treatment includes placing at least one applicator in contact with the patient's body. The applicator has at least one electrode. Electrotherapy and radio frequency therapy are provided to the soft tissue, optionally with overlay or sequentially. A handheld applicator may be used, with the applicator moving during the therapy, which may provide muscle stimulation in the patient, or provide an analgesic effect during the treatment. A spacing object may be positioned between the skin of the patient and the applicator.

Abstract: Various embodiments of a hermetically-sealed package and a method of forming such package are disclosed. The package includes a housing that extends along a housing axis between a first end and a second end, where the housing includes first and second opaque portions and a transparent portion disposed between the first and second opaque portions. The first opaque portion is hermetically sealed to a first end of the transparent portion and the second opaque portion is hermetically sealed to a second end of the transparent portion. At least one of the first and second opaque portions is hermetically sealed to the transparent portion by a weld ring. The package further includes a power source disposed within the housing, and an inductive coil disposed at least partially within the transparent portion of the housing and electrically connected to the power source.

Abstract: According to one aspect, an implantable medical device may include an anchor assembly configured to anchor the medical device to a body lumen. The implantable medical device may also include a capsule. The capsule may include a pH sensor. The pH sensor may be configured to measure a pH of contents within the body lumen. The capsule may also include a power source, a controller, and an impedance sensor. The impedance sensor may be configured to measure an impedance within the body lumen.

Abstract: A system for delivering electrical pulse stimulation to a subject includes a remote control device configured to at least intermittently transmit temporal pulse pattern programming and a stimulation device comprising a control interface, at least one electrode in electrical communication with the control interface, and an input device in at least intermittent communication with the remote control device to receive the temporal pulse pattern programming. The stimulation device is configured to deliver electrical pulse stimulation to a subject via the at least one electrode according to the temporal pulse pattern programming.

Abstract: A method of monitoring neural activity responsive to a stimulus in a brain, the method comprising: applying the stimulus to one or more of at least one electrode implanted in a target neural structure of the brain; detecting a resonant response from the target neural structure evoked by the stimulus at one or more of the at least one electrode in or near the target neural structure of the brain; and determining one or more waveform characteristics of the detected resonant response.

Abstract: The present invention generally relates to an image-guided laser irradiation device for targeted ablation, stimulation, molecular delivery and therapy. Specifically, the invention relates to application of the device in therapies needing precise and targeted removal of a sample, or delivery of impermeable molecules for therapeutic outcome. More specifically, the invention relates to the application of the device in the therapy of visual disorders.

Abstract: Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

Abstract: A computer-implemented system includes one or more processing devices configured to receive attribute data associated with a user, generate, based on a pulmonary condition of the user, a selected set of the attribute data, determine, based on the selected set of the attribute data, a first probability of improving a pulmonary condition of the user subsequent to at least one of a pulmonary procedure being performed on the user, a pulmonary treatment being performed on the user, and a pulmonary diagnosis, and generate, based on the first probability, a treatment plan that includes one or more exercises directed to modifying the first probability. A treatment apparatus is configured to enable implementation of the treatment plan.

Abstract: A surgical hub for controlling a display using situational awareness of a medical instrument may be provided. A user, a medical instrument, and a location within an operating room may be determined. Contextual data associated with the medical instrument may be determined based on the user, the medical instrument, and the location within the operating room. A display instruction may be sent to a display that may instruct the display to be configured in accordance with contextual data associated with the medical instrument.

Abstract: This disclosure describes systems and methods for electrocardiographic waveform analysis, data presentation and actionable advisory generation. Electrocardiographic waveform data can be received from a wearable device associated with a patient. A mathematical analysis can be performed on the electrocardiographic waveform data to provide cardiac analytics. A visualization of the cardiac analytics on a dashboard display can be generated. A value can be based on a comparison of the cardiac analytics to at least one baseline value for the patient; and a decision of whether or not to generate an actionable advisory for the electrocardiographic waveform data can be made based on the value. When the actionable advisory is generated, the actionable advisory is sent to one or more medical professionals, where it can be modified, and displayed with the visualization of the cardiac analytics.

Abstract: A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes.

Abstract: An apparatus and a method are described in which a signal is received from a gyroscope sensor mounted on a subject. The gyroscope sensor is configured to measure rotational movement of the subject's heart, the signal being indicative of a left ventricular twist of the subject's heart. A change in the left ventricular twist of the subject's heart caused by occlusion of blood flow by an arterial occlusion device configured to selectively occlude blood flow of the subject is determined.

Abstract: A cardiac defibrillation system that includes a pulse generator to generate therapeutic electrical pulses and at least one lead inserted through an intercostal space in the region of a cardiac notch of the left lung of a patient, the lead having a distal end configured to transmit the therapeutic electrical pulses generated by the pulse generator to defibrillate the heart of the patient.

Abstract: A wearable defibrillator for use in monitoring patient movement and cardiac activity and treating a patient includes a garment configured to be worn by the patient, treatment electrodes configured to apply an electric current to the patient, and an alarm module configured to provide audio, visual, and haptic notifications. The notifications are configured to indicate that an electric current will be administered imminently and prompt the patient to provide a response input. The wearable defibrillator includes a motion sensor configured to detect motion and body position of a patient, and a controller in electrical communication with the alarm module and the motion sensor. The controller is configured to monitor for the response input after the prompt, determine, based on the detected motion and body position, whether the patient is sleeping, and cause a change in one or more characteristics of the prompt on determining that the patient is sleeping.

Abstract: A system and method for obtaining an OIS coordinate frame comprising an electronic control unit configured to determine a local 3D electric field loop, create a zero mean version of E(t) over a depolarization interval, compute an ? value at each of a plurality of time intervals, compute an initial estimate of ? from a cross product of E and the ? value for each of the plurality of time intervals, average the initial estimate of ? from each of the plurality of time for a best estimate of ?, determine a plurality of â(?) values and using the corresponding {circumflex over (n)}(?) values, compute a composite match score, and choose at least one best value for â and a best value for {circumflex over (n)}.

Abstract: Waveforms for a stimulator device, and methods and circuitry for generating them, are disclosed having high- and low-frequency aspects. The waveforms comprise a sequence of pulses issued at a low frequency which each pulse comprising first and second charge-balanced phases. One or both of the phases comprises a plurality a monophasic sub-phase pulses issued at a high frequency in which the sub-phase pulses are separated by gaps. The current during the gaps in a phase can be zero, or can comprise a non-zero current of the same polarity as the sub-phase pulses issued during that phase. The disclosed waveforms provide benefits of high frequency stimulation such as the promotion of paresthesia free, sub-threshold stimulation, but without drawbacks inherent in using high-frequency biphasic pulses.

Abstract: A computer-implemented method for facilitating cardiac rehabilitation among eligible users is disclosed. The method includes the steps of (1) receiving health information associated with one or more users; (2) for each user of the one or more users: determining, based on health information associated with the user, a respective eligibility of the user for cardiac rehabilitation; (3) determining, based on the respective eligibilities, that at least one user of the one or more users is eligible for cardiac rehabilitation; (4) generating a treatment plan for the at least one user, where the treatment plan pertains to a cardiac rehabilitation that is specific to the at least one user; and (5) assigning the treatment plan to at least one electromechanical machine to enable the user to perform the cardiac rehabilitation.