Abstract: Therapeutic amounts of DHEA are administered to human patients for the treatment and prevention of such disorders as atherosclerosis, angina, diabetes, obesity and congestive heart failure. Administering therapeutic quantities of DHEA to human patients has been found to reduce body fat mass and increase muscle mass, lower serum LDL cholesterol levels, lower serum apoB levels, and not affect tissue sensitivity to insulin.
Type:
Grant
Filed:
December 28, 1988
Date of Patent:
April 24, 1990
Assignee:
Virginia Commonwealth University
Inventors:
John E. Nestler, Cornelius O. Barlascini, John N. Clore, William G. Blackard