Abstract: 5-Amino or substituted amino imidazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling cecal and or intestinal coccidiosis when administered in minor quantitites to animals, in particular to poultry, usually in admixture with animal sustenance.

Abstract: New esters of 1,4-dihydropyridine (and their salts) are prepared which are useful as pharmacologically active ingredients in particular in medicaments for the preventive and curative treatment of cardiovascular disorders.Said esters have for formula ##STR1## where R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, X and Y and index n are defined as in claim 1.

Abstract: Compounds of the formula: ##STR1## and pharmaceutically-acceptable acid addition salts thereof, wherein R.sup.1 is at the 3 or 4 position and is phenyl or phenyl substituted by halo, (C.sub.1 -C.sub.4)alkoxy, or (C.sub.2 -C.sub.5)alkoxycarbonyl; R.sup.2 is at the 2 or 7 position and is a group of the formula X(CH.sub.2).sub.n NR.sup.3 R.sup.4 where X is --CH.dbd.CH-- or --(CH.sub.2).sub.2 --; n is 1, 2, 3 or 4; and each of R.sup.3 and R.sup.4 is hydrogen or (C.sub.1 -C.sub.4)alkyl, or R.sup.3 and R.sup.4 together with the nitrogen atom to which they are attached form a 1-pyrrolidinyl or piperidino group; Y is hydrogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy or (C.sub.2 -C.sub.5)-alkoxycarbonyl at the 4, 5, 6 or 7 position; and wherein R.sup.2 is at the 2-position, R.sup.1 is at the 3- or 4-position, or alternatively when R.sup.2 is at the 7-position, R.sup.1 is at the 3-position; are useful for the treatment of diarrhea in humans and animals.

Abstract: The invention concerns:Novel dibenz/b,e/oxepin and dibenz/b,e/thiepin compounds having the general formula: ##STR1## wherein X is O or S,R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same or different and are each selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower cycloalkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulponyl, halogen, trifluoromethyl, trifluoromethylthio, lower dialkylsulphonamido, nitro, hydroxy, cyano, carbamyl, carboxy, lower alkoxycarbonyl, amino, N-lower alkylamino, N,N-diloweralkylamino, lower acylamido, lower alkanesulfonamido and lower acyl and, when on adjacent carbon atoms at the positions 2 and 3 and/or 8 and 9, two of the substituents R.sup.1 and R.sup.2 or R.sup.3 and R.sup.4 taken together may form a methylenedioxy group;R.sup.5 and R.sup.

Abstract: A phenol derivative represented by the formula ##STR1## wherein R.sup.1 is a secondary or tertiary hydrocarbon residue of having 3 to 8 carbon atoms, R.sup.2 is a hydrocarbon residue having 1 to 12 carbon atoms, X is ##STR2## wherein R.sup.3, R.sup.4 and R.sup.5 each is an alkylene group having 1 to 4 carbon atoms, Z is an n-valent group and n is an integer of 1 to 8.This compound is effective to prevent the oxidation of organic materials.

Abstract: New .beta.-carboline-3-carboxylic acid esters have the general formula I: ##STR1## wherein R.sup.4, R.sup.5 and R.sup.6 have specified meanings. The new compounds exhibit surprising psychotropic properties.

Abstract: The present invention relates to a novel four-step process for the preparation of herbicidal and plant growth regulating 2-nitro-5-(2-pyridinyloxy)acetophenone oxime ether derivatives of formula I ##STR1## wherein R.sup.1 is hydrogen, cyano, halogen, nitro, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 haloalkyl,R.sup.2 is hydrogen or halogen,R.sup.3 is C.sub.1 -C.sub.4 alkyl andR.sup.4 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 cyanoalkyl, C.sub.3 -C.sub.5 alkenyl, C.sub.3 -C.sub.5 -haloalkenyl, C.sub.3 -C.sub.5 alkynyl, or C.sub.1 -C.sub.4 alkyl which is substituted by C.sub.1 -C.sub.4 alkoxy, halogen, C.sub.1 -C.sub.4 alkoxycarbonyl, C.sub.1 -C.sub.4 alkylaminocarbonyl or di(C.sub.1 -C.sub.4)alkylaminocarbonyl,which process comprises converting a phenol of formula II ##STR2## by reaction with a compound of formulaH.sub.2 N--O--R.sup.

Abstract: N-(2,6-Disubstitutedphenyl)-N'-3- and 4-pyridinyl ureas and pharmaceutically acceptable acid addition salts having anticonvulsant activity are described as well as a process for their manufacture, formulations containing the compounds and a method of treating epilepsy using the compounds in unit dosage form.

Abstract: Disclosed is a process for producing a heterocyclic compound having a nitromethylene group as the side chain, of the formula ##STR1## wherein Y represents a hydrogen atom, a halogen atom or a lower alkyl group, R represents a hydrogen atom, an alkyl group, a cycloalkyl group, an aralkyl group, an alkenyl group, an alkynyl group or an acyl group, and n represents an integer of 2, 3 or 4,which comprises reacting a 2,2,2-trihalo-1-nitroethane compound with a 1-aminoalkanethiol compound or a 1-N-substituted derivative thereof.

Abstract: 4-(Nitrophenyl)-1,2,3,4-tetrahydropyridines of the formula ##STR1## in which R.sub.1 and R.sub.2 are identical or different and each represent hydrogen, phenyl or a straight-chain or branched alkyl radical which is optionally substituted by halogen or alkoxy,R.sub.3 represents a straight-chain or branched alkyl radical which is optionally substituted by alkoxy, halogen, alkylamino or aryl,X represents a single bond, an oxygen atom, a sulphur atom or the NH group andY denotes either the nitrile group or the radical ##STR2## wherein X' corresponds to the definition of X and can either be identical to X or different from X, andR.sub.4 corresponds to the definition of R.sub.3 and can be either identical to R.sub.3 or different from R.sub.3,or physiologically acceptable salts thereof, which are active on the circulation system, for example as vasodilators.

Abstract: Disclosed are the compounds of formula I ##STR1## wherein X represents oxygen or sulfur; ring A is unsubstituted or substituted by one to three identical or different substituents selected from hydroxy, hydroxy-lower alkyl, etherified hydroxy, etherified hydroxy-lower alkyl, acyloxy, acyloxy-lower alkyl, halogen, lower alkyl, trifluoromethyl, amino, mono- and di-lower alkylamino and acylamino; or ring A is substituted by one lower alkylenedioxy; R represents hydrogen, lower alkyl or aryl-lower alkyl; R.sub.1 represents hydrogen, lower alkyl, lower alkylthio-lower alkyl, amino, acylamino, (amino, mono- or di-lower alkylamino)-lower alkyl, carboxy, lower alkoxycarbonyl, carbamoyl or mono- or di-lower alkylcarbamoyl; R.sub.2 to R.sub.5 represent hydrogen or lower alkyl; the dehydro derivatives thereof with a double bond at the 1,2-position, or at the 1,10b-position in which case R.sub.

Abstract: Described is the genus of thiogeranyl esters defined according to the structure: ##STR1## wherein R represents hydrogen, C.sub.1 -C.sub.5 alkyl or C.sub.2 -C.sub.6 alkenyl and uses thereof in augmenting or enhancing the aroma or taste of consumable materials including foodstuffs, chewing gums, toothpastes, medicinal products, perfume compositions, colognes and perfumed articles.

Abstract: 1,4-Dihydropyridine derivatives of the formula: ##STR1## wherein R is aryl or heteroaryl; R.sup.1 and R.sup.2 are each independently C.sub.1 -C.sub.4 alkyl or 2-methoxyethyl; X is a 5 or 6 membered nitrogen-containing heterocyclic ring which is substituted with one or more hydroxyl or oxo groups and which may optionally be fused to a further 5 or 6 membered nitrogen-containing heterocyclic ring, and which may optionally be further substituted in the heterocyclic ring or further fused heterocyclic ring; Y is --(CH.sub.2).sub.n --, --CH.sub.2 CH(CH.sub.3)-- or --CH.sub.2 C(CH.sub.3).sub.2 --; and n is 1 to 3 when X is linked to Y by a ring carbon atom, or 2 or 3 when X is linked to Y by a ring nitrogen atom; and their pharmaceutically acceptable salts, and pharmacuetical preparation containing such compounds, have utility as anti-ischaemic and antihypertensive agents.

Abstract: It has been found that phosphoric acid alone and in admixture with phenothiazine and/or methyl-p-benzoquinone reduces residue formed during the fractionation of aqueous crude maleic compositions for the production of maleic anhydride, and in particular, reduces residue due to the presence of small amounts, i.e., less than 10 ppm alkali metal ion. When the alkali metal ion is present at least 9 equivalent acid groups of phosphoric acid per atomic equivalent of alkali metal ion are present.

Abstract: Compounds of the formula 1: ##STR1## wherein: X is O or S;R.sub.1 is hydrogen, or CO.sub.2 R.sub.1 represents an ester group in which the R.sub.1 moiety contains from 1-12 carbon atoms;R.sub.2 is hydrogen or C.sub.1-4 alkyl;R.sub.4 is C.sub.1-9 alkyl, C.sub.3-8 cycloalkyl or C.sub.3-8 cycloalkyl-C.sub.1-6 alkyl; orR.sub.2 and R.sub.4 taken with the carbon atom to which they are joined represent a C.sub.5-8 cycloalkyl group; andR.sub.5 is C.sub.1-6 alkyl; and salts thereof, having similar activity to natural prostaglandins, a process for their preparation, intermediates useful in that process and pharmaceutical compositions containing them.

Abstract: Compounds having the formula ##SPC1##Where X is S, SO or SO.sub.2 and Y and Y.sup.1 are the same or different and each is H, OH, O.sup.. or a straight- or branched alkyl residue having from 1 to 4 carbon atoms, and salts thereof when Y and Y.sup.1 are other than O.sup.. are useful as stabilisers for organic materials such as diene rubbers.