Patents Examined by Jacqueline Brazin
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Patent number: 11333661Abstract: A detection analyzer including a first sample input/output element, a second sample input/output element, a sample compartment, a vibration platform, a vibration generator, a data acquisition system, a laser converter, and a data display. The first sample input/output element and the second sample input/output element are each connected to the sample compartment; the vibration platform is located inside the sample compartment; the vibration generator is located outside the sample compartment, and the vibration platform is connected to the vibration generator; the data acquisition system is located outside the sample compartment, and is connected to the vibration platform; and the data display is connected to the data acquisition system.Type: GrantFiled: January 9, 2018Date of Patent: May 17, 2022Assignees: CIXI INSTITUTE OF BIOMEDICAL ENGINEERING NINGBO INSTITUTE OF INDUSTRIAL TECHNOLOGY, CHINESE ACADEMY OF SCIENCES, NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCESInventors: Fang Yang, Aiguo Wu
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Patent number: 11333663Abstract: A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer.Type: GrantFiled: May 7, 2020Date of Patent: May 17, 2022Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Timothy Manning Swager, Joseph Michael Azzarelli, Shinsuke Ishihara
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Patent number: 11333674Abstract: A test kit of the present invention includes an analysis chip and a pipette tip. The pipette tip includes: a first portion coming in contact with an insertion hole hermetic seal when the pipette tip is inserted into a pipette tip insertion portion so as to allow a liquid dispensation port to be positioned at or in the vicinity of a bottom surface of the pipette tip insertion portion; and a second portion positioned closer to the liquid dispensation port side than the first portion. The outer diameter of the second portion is formed to be equal to or greater than the outer diameter of the first portion and any portion between the first portion and the second portion.Type: GrantFiled: November 7, 2016Date of Patent: May 17, 2022Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Mami Takeuchi, Masataka Matsuo
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Patent number: 11333583Abstract: An extraction portion which is a piece of a micro sampling chip is safely cut, and the cut extraction portion can be accommodated in a predetermined container without impairing quantitativeness of a sample. A sample extraction tool comprises a through hole for cutting the extraction portion from the micro sampling chip by bending the micro sampling chip while inserting the extraction portion to the through hole, the sample extraction tool is configured to be attached to an upper portion of a container for accommodating the extraction portion in such a state that the through hole is disposed on an open upper surface of the container.Type: GrantFiled: May 9, 2019Date of Patent: May 17, 2022Assignee: SHIMADZU CORPORATIONInventor: Nobuhiro Hanafusa
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Patent number: 11307184Abstract: Sensors arrays that include indicators arranged in a pattern on a substrate. The indicators include nucleophilic indicators. In some examples, the sensor arrays with multiple nucleophilic indicators provide superior detection and identification of microorganisms, cancer biomarkers, formaldehyde, organophosphates, and aldehydes.Type: GrantFiled: February 15, 2018Date of Patent: April 19, 2022Assignee: iSense LLCInventors: Sung Hyun Lim, Autumn Maruniak, Nuria Queralto Gratacos
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Patent number: 11305286Abstract: The invention relates to a collection assembly (1) for small amounts of body fluids, comprising a sample container (2) and an extender element (3). The sample container (2) has a base (13) and a container wall (5) with a first container wall section (6) and a second container wall section (7) adjoining same. The second container wall section (7) is formed hollow-conically and projects into the extender element (3). Moreover, a coupling device (25) with a first coupling element (26) and a second coupling element (27) is provided. When the coupling elements (26, 27) are in coupled engagement, the extender element (3) is coupled to the sample container (2) in a positively locked manner in the form of a snap connection establishing the collection assembly (1).Type: GrantFiled: April 25, 2018Date of Patent: April 19, 2022Assignee: Greiner Bio-One GmbHInventors: Franz Ebetsberger, Arnold Boeck
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Patent number: 11307164Abstract: A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid, and a membrane comprising a test line for determining whether the fluid comprises a target analyte. The device includes an actuator connected to a moving element comprising a shaft or a wheel. A first magnet is connected to the backing of the membrane. Second and third magnets are connected to the moving element. The actuator moves the moving element between first and second positions. In the first position, the opposite poles of the first and second magnets attract each other and maintain a gap between the membrane and the conjugate pad separate. In the second position, the similar poles of the first and third magnets repel each other and close the gap between membrane and the conjugate pad, allowing the fluid to flow from the conjugate pad into the membrane and the test line.Type: GrantFiled: May 27, 2021Date of Patent: April 19, 2022Assignee: 2Pi-Sigma Corp.Inventor: Mehdi Hatamian
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Patent number: 11299728Abstract: A fluid sample extraction device is disclosed comprising a housing defining an internal fluid passage having a distal open end and a proximal open end and a porous medium within the fluid passage, between the distal open end and proximal open end. The porous medium, which may be glass, is configured to allow fluid flow in the fluid passage to flow around the porous medium, toward the proximal open end of the housing, when fluid is drawn from the distal open end toward the proximal open end, and to allow fluid in the fluid passage to flow toward the distal open end of the housing, through the porous medium when the fluid is forced toward the distal open end. The porous medium is also configured to capture nucleic acids in the porous medium from the fluid when fluid is forced through the porous medium. Devices and kits are also disclosed.Type: GrantFiled: June 11, 2020Date of Patent: April 12, 2022Assignee: Biomeme, Inc.Inventors: Marc Dominic DeJohn, Jesse Wilson vanWestrienen
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Patent number: 11284867Abstract: A biological sample collection system can include (i) a sample collection vessel having an opening for receiving a biological sample, (ii) a selectively movable valve comprising a core and a collar disposed about the core, and (iii) a sealing cap coupled to the collar and comprising a reagent chamber for storing a measure of sample preservation reagent. The sealing cap is configured to associate—and form a fluid tight connection—with the sample collection vessel such that associating the sealing cap with the sample collection vessel causes a physical rearrangement of the core relative to the collar such that a fluid vent associated with the core is moved into fluid communication with the reagent chamber, thereby permitting sample preservation reagent to pass from the regent chamber to the sample collection vessel.Type: GrantFiled: November 10, 2020Date of Patent: March 29, 2022Assignee: SPECTRUM SOLUTIONS L.L.C.Inventor: Neil Jeremy Johnson
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Patent number: 11278903Abstract: The invention relates to a test cell for mixing a liquid. The test cell comprises an interior space for receiving the liquid and a running rail, which is formed in the interior space, for a ball, wherein the running rail is formed by two projections which project into the interior space from opposite side walls of the test cell. According to the invention, the running rail has a straight section and is deflected upward at both ends. In the test cell according to the invention, a high filling level can be achieved with a low quantity of liquid, this being advantageous for optical measurements. The invention also relates to a measuring method using the test cell.Type: GrantFiled: November 16, 2016Date of Patent: March 22, 2022Inventor: Holger Behnk
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Patent number: 11275051Abstract: Metal oxide-based integrated chemical sensors using a hybrid polycrystalline gas-sensitive material to create a uniform and integrated sensory system. The sensor system provides the unique properties such as improved sensor sensitivity due to reduced thickness, improved selectivity for specific analyte detection in the ppb, faster time of response, decreased time of reset and decreased power consumption in comparison to existing sensor technologies. The present invention also provides novel, metal oxide-based chemical sensor platforms, a novel method of making metal oxide-based chemical sensors, platforms and/or integrated chemical sensors.Type: GrantFiled: September 23, 2020Date of Patent: March 15, 2022Assignee: VAON, LLCInventors: Vladimir Dobrokhotov, Alexander Larin
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Patent number: 11243220Abstract: A device and method for purification of information or particles from a sample and provides a device for performing washing steps in automated analyzer systems, the device comprising a multilayer unit with liquid channel and valves. The multilayer unit may comprise three layer.Type: GrantFiled: September 20, 2017Date of Patent: February 8, 2022Assignee: STRATEG SEInventors: Volker Barenthin, Tuna Sinangin
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Patent number: 11235332Abstract: A novel in vitro system and method for predicting the in vivo behavior, such as absorption time or mechanical strength retention, of biodegradable polymeric implants and medical devices. Data from this in vitro method are correlated to in vivo absorption data, allowing for the prediction of accurate in vivo behaviors, such as absorption times. The system uses a novel bypass loop to maintain the integrity of pH measuring devices to improve the reproducibility of data collected during in vitro testing.Type: GrantFiled: June 14, 2018Date of Patent: February 1, 2022Assignee: Ethicon, Inc.Inventors: Yuxin Han, Yuewu Chen, Dechun Wu
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Patent number: 11207681Abstract: The present invention provides an extraction cassette, which includes an extraction module. The extraction module includes an extraction module body, an expansion compartment, a reaction compartment, a filter, a collection compartment, a first waste-liquid compartment and a second waste-liquid compartment. The expansion compartment is formed on the extraction module body. The reaction compartment includes a reaction compartment inlet, a reaction compartment outlet and a reaction compartment notch, the expansion compartment is connected to the reaction compartment notch, and the reaction compartment notch is located between the reaction compartment inlet and the reaction compartment outlet. The filter is disposed in the reaction compartment and corresponding to the reaction compartment outlet. The collection compartment communicates with the reaction compartment outlet. The first waste-liquid compartment communicates with the reaction compartment outlet.Type: GrantFiled: December 21, 2018Date of Patent: December 28, 2021Assignee: DELTA ELECTRONICS, INC.Inventors: Wei-Yu Chung, Song-Bin Huang, Shing-Lun Liu, Yu-Kai Kao, Yi-Chen Li
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Patent number: 11211151Abstract: A method of obtaining and analyzing at least one tissue sample includes forming, in a tissue container, first tracking data associated with the at least one tissue sample. Second tracking data is formed, in a transport container. The second tracking data is associated with the at least one tissue sample. The at least one tissue sample is placed in the tissue container. The first and second tracking data from the tissue container and the transport container are scanned with an electronic scanning system to ensure that the first and second tracking data are both associated with the removed tissue sample.Type: GrantFiled: June 30, 2017Date of Patent: December 28, 2021Assignee: Devicor Medical Products, Inc.Inventors: Adam Walter, Elijah Kreider, Bryan R. Keller
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Patent number: 11199481Abstract: A sample analysis appliance for the analysis of a sample solution, in particular of contaminated water or of waste water, with a reaction vessel for the thermal digestion of a portioned sample of the sample solution to be analyzed. The reaction vessel has an injection port for the introduction of the sample into the reaction vessel, at least one sample solution storage vessel for the device-internal storage of sample solution, and an injection syringe device which is movable between the sample solution storage vessel and the reaction vessel and which can be controlled to collect the sample from the sample solution storage vessel and introduce the sample into the injection port of the reaction vessel.Type: GrantFiled: October 31, 2016Date of Patent: December 14, 2021Assignee: LAR Process Analysers AGInventors: Werner Arts, Olivia Arts, Martin Glittenberg
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Patent number: 11193915Abstract: A composite material for sensing a chemical species in a medium is provided. The composite material includes a polymer having a glass transition temperature, a porosity promoter dispersed in the polymer in an amount such that the chemical species is transportable from the medium into the composite material at a temperature below the glass transition temperature, and a chemical indicator dispersed in the composite material, the chemical indicator providing an optical response varying with a concentration of the chemical species in the composite material.Type: GrantFiled: November 28, 2016Date of Patent: December 7, 2021Assignee: INSTITUT NATIONAL D'OPTIQUEInventors: Sebastien Dubus, Serge Caron, Nolwenn Le Bouch, Antoine Proulx
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Patent number: 11187680Abstract: Surface modifications and improvements to piezoelectric-based sensors, such as QCMs and other piezoelectric devices, that significantly increase the sensitivity and the specificity (selectivity). These modifications can comprise mechanical and chemical changes to the surfaces of the sensors, either individually or together. For example, nanosize structures may be provided on the surface to improve sensitivity. Additionally, chemical coatings may be tethered to the surfaces, walls, or crystal to provide targeted sensitivity. Additionally, porous, layered and multiple sensor arrays may be formed to enhance sensitivity and selectivity.Type: GrantFiled: March 22, 2019Date of Patent: November 30, 2021Assignee: SYRACUSE UNIVERSITYInventors: Fritz H. Schlereth, James Spencer
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Patent number: 11181459Abstract: A particle vapor reactor (PVR) includes a reactor body with a fluid flow conduit having an inlet end and an outlet end, the crossection of the conduit having a circular geometry at the inlet end, a rectangular geometry at its midsection, and a circular geometry at its outlet end. The PVR conduit defines a saturator section and a condenser section. A compact condensation particle counter (CPC) including the reactor is also disclosed. The CPC also includes a sample inlet, a fluid inlet section, a heater section, and a detector section.Type: GrantFiled: March 23, 2017Date of Patent: November 23, 2021Assignee: KANOMAX-FMT, Inc.Inventor: Derek Oberreit
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Patent number: 11169057Abstract: A particle dispersion method for dispersing particles (500) fixed on the inner surface of a container (12) into a liquid. The particle dispersion method includes a discharge step of discharging a liquid into the container (12). The container (12) has a cylindrical main body part (310), and an inclined part (311) having an inner diameter that decreases from the main body part (310) side to the bottom part side and having a constant angle relative to the central axis of the container. In the discharge step, the liquid is discharged from above the inclined part (311) toward the inclined part (311) on the side opposite the particles (500) fixed to the inner surface of the container (12) across the central axis (300) of the container (12).Type: GrantFiled: November 29, 2017Date of Patent: November 9, 2021Assignee: Sysmex CorporationInventors: Hiroaki Tobimatsu, Toshimi Sato