Abstract: A prefilled syringe of cartridge barrel having a tamper evident closure. Tamper evidence is provided by: a frangible tip seal which is integral with the tapered tip of the barrel; a frangible tip cap covering the tip, the tip seal and a portion of the distal end of the barrel; and an overwrap covering the frangible tip cap and the distal end of the barrel sealed to the distal end of the barrel by a tamper evident seal. The tapered tip is optionally equipped with a luer collar to receive an external luer connector. Alternatively, the tapered tip can be provided with a bore therethrough which can be closed with an elastomeric plug and the external connector can be a tubing conduit.
Type:
Grant
Filed:
October 7, 2002
Date of Patent:
April 27, 2004
Assignee:
Bracco Diagnostics, Inc.
Inventors:
Michael N. Eakins, Ernest Balestracci, Ernst Schramm, John J. Niedospial, Jr.